Ddx52 (DExD-box helicase 52) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Ddx52 (DExD-box helicase 52) Heterocephalus glaber
Analyze
Symbol: Ddx52
Name: DExD-box helicase 52
RGD ID: 18931799
Description: ENCODES a protein that exhibits ATP binding (inferred); helicase activity (inferred); hydrolase activity (inferred); INVOLVED IN maturation of SSU-rRNA (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); chromosome 17q12 deletion syndrome (ortholog); FOUND IN cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DEAD-box helicase 52; probable ATP-dependent RNA helicase DDX52; putative ATP-dependent RNA helicase DDX52
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248714,596,313 - 4,622,634 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Ddx52
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248714,596,313 - 4,622,634 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DDX52
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381737,609,739 - 37,643,446 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1737,609,739 - 37,643,446 (-)EnsemblGRCh38hg38GRCh38
GRCh371735,969,787 - 36,003,475 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361733,046,526 - 33,077,600 (-)NCBINCBI36Build 36hg18NCBI36
Build 341733,046,525 - 33,077,600NCBI
Celera1732,795,453 - 32,826,538 (-)NCBICelera
Cytogenetic Map17q12NCBI
HuRef1731,909,783 - 31,940,869 (-)NCBIHuRef
CHM1_11736,003,881 - 36,035,027 (-)NCBICHM1_1
T2T-CHM13v2.01738,596,713 - 38,630,405 (-)NCBIT2T-CHM13v2.0
Ddx52
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391183,831,659 - 83,853,914 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1183,832,888 - 83,853,914 (+)EnsemblGRCm39 Ensembl
GRCm381183,942,090 - 83,963,088 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1183,942,062 - 83,963,088 (+)EnsemblGRCm38mm10GRCm38
MGSCv371183,755,592 - 83,776,590 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361183,758,373 - 83,778,385 (+)NCBIMGSCv36mm8
Celera1193,547,131 - 93,568,131 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1151.24NCBI
Ddx52
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81069,322,062 - 69,344,856 (+)NCBIGRCr8
mRatBN7.21068,824,594 - 68,847,400 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1068,824,645 - 68,848,266 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1073,444,647 - 73,467,375 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01072,949,656 - 72,972,384 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01068,414,078 - 68,436,804 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01071,253,667 - 71,276,397 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1071,253,598 - 71,277,277 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01070,864,522 - 70,888,590 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41072,222,689 - 72,245,419 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11072,237,058 - 72,259,788 (+)NCBI
Celera1067,754,185 - 67,776,912 (+)NCBICelera
Cytogenetic Map10q26NCBI
Ddx52
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955451409,249 - 438,951 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955451409,827 - 437,757 (+)NCBIChiLan1.0ChiLan1.0
DDX52
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21927,110,284 - 27,140,265 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11728,993,807 - 29,023,696 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01719,433,036 - 19,466,975 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11719,734,568 - 19,764,235 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1719,734,588 - 19,763,689 (+)Ensemblpanpan1.1panPan2
DDX52
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1937,368,243 - 37,390,526 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha936,591,966 - 36,614,581 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0938,178,409 - 38,201,242 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl938,178,113 - 38,201,194 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1936,959,168 - 36,982,024 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0937,246,741 - 37,269,434 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0937,333,761 - 37,356,661 (-)NCBIUU_Cfam_GSD_1.0
Ddx52
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560236,315,998 - 36,323,696 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936490743,482 - 760,712 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936490743,482 - 758,886 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDX52
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1239,072,314 - 39,143,685 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11239,072,310 - 39,095,558 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21240,713,951 - 40,739,656 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DDX52
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11630,138,075 - 30,168,803 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1630,138,084 - 30,170,332 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666077861,831 - 892,190 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_004870423   ⟹   XP_004870480
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248714,596,313 - 4,622,634 (-)NCBI
RefSeq Acc Id: XR_002391108
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248714,596,313 - 4,622,634 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004870480 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000008651
  ENSHGLP00100060799
GenBank Protein JAO02074 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004870480   ⟸   XM_004870423
- UniProtKB: A0A0P6JCG2 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000006235 ENTREZGENE
  ENSHGLG00100013765 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000008744 ENTREZGENE
  ENSHGLT00100075018 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro DDX52/Rok1_DEADc UniProtKB/TrEMBL
  DEAD/DEAH_box_helicase_dom UniProtKB/TrEMBL
  DEAD_box_RNA_helicase UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RNA_helicase_DEAD_Q_motif UniProtKB/TrEMBL
KEGG Report hgl:101710449 UniProtKB/TrEMBL
NCBI Gene Ddx52 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE UniProtKB/TrEMBL
  ATP-DEPENDENT RNA HELICASE RHLE-RELATED UniProtKB/TrEMBL
Pfam DEAD UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
PROSITE HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
  Q_MOTIF UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0P6JCG2 ENTREZGENE, UniProtKB/TrEMBL