Lrfn2 (leucine rich repeat and fibronectin type III domain containing 2) - Rat Genome Database

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Gene: Lrfn2 (leucine rich repeat and fibronectin type III domain containing 2) Heterocephalus glaber
Analyze
Symbol: Lrfn2
Name: leucine rich repeat and fibronectin type III domain containing 2
RGD ID: 18930981
Description: INVOLVED IN modulation of chemical synaptic transmission (ortholog); regulation of postsynapse organization (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN postsynapse (ortholog); postsynaptic density membrane (ortholog); presynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Leucine-rich repeat and fibronectin type-III domain-containing protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475418,169,513 - 18,201,639 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475418,054,520 - 18,201,529 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Lrfn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475418,169,513 - 18,201,639 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475418,054,520 - 18,201,529 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
LRFN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38640,391,591 - 40,587,364 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl640,391,591 - 40,587,364 (-)EnsemblGRCh38hg38GRCh38
GRCh37640,359,330 - 40,555,103 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36640,467,351 - 40,663,104 (-)NCBINCBI36Build 36hg18NCBI36
Celera641,912,256 - 42,107,705 (-)NCBICelera
Cytogenetic Map6p21.2-p21.1NCBI
HuRef640,076,973 - 40,272,680 (-)NCBIHuRef
CHM1_1640,361,750 - 40,557,459 (-)NCBICHM1_1
T2T-CHM13v2.0640,219,487 - 40,415,195 (-)NCBIT2T-CHM13v2.0
Lrfn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391749,238,630 - 49,404,619 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1749,239,407 - 49,404,616 (+)EnsemblGRCm39 Ensembl
GRCm381748,931,590 - 49,097,591 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1748,932,379 - 49,097,588 (+)EnsemblGRCm38mm10GRCm38
MGSCv371749,071,907 - 49,236,915 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361748,397,946 - 48,563,155 (+)NCBIMGSCv36mm8
Celera1752,367,169 - 52,531,112 (+)NCBICelera
Cytogenetic Map17CNCBI
cM Map1724.66NCBI
Lrfn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8919,395,099 - 19,563,849 (-)NCBIGRCr8
mRatBN7.2911,897,425 - 12,066,177 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl911,897,468 - 11,939,931 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx920,403,200 - 20,434,776 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0925,469,396 - 25,500,976 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0923,856,849 - 23,888,562 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0913,845,756 - 14,015,360 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl913,845,757 - 13,877,130 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0912,776,271 - 12,943,378 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.497,109,376 - 7,141,595 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.197,109,333 - 7,313,632 (-)NCBI
Celera99,672,139 - 9,703,921 (-)NCBICelera
Cytogenetic Map9q12NCBI
Lrfn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554377,201,978 - 7,358,626 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554377,202,466 - 7,358,616 (-)NCBIChiLan1.0ChiLan1.0
LRFN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2554,880,033 - 55,075,266 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1650,750,011 - 50,945,189 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0639,972,362 - 40,167,612 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1641,282,633 - 41,477,067 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl641,282,940 - 41,477,073 (-)Ensemblpanpan1.1panPan2
LRFN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1129,202,552 - 9,248,682 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl129,169,667 - 9,388,109 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha129,239,653 - 9,417,449 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0129,685,895 - 9,865,789 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl129,685,818 - 9,865,680 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1129,219,600 - 9,397,270 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0129,296,393 - 9,474,527 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0129,397,023 - 9,575,112 (-)NCBIUU_Cfam_GSD_1.0
Lrfn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494644,591,901 - 44,752,579 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647619,330,102 - 19,366,081 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647619,207,623 - 19,368,301 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRFN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl735,723,797 - 35,914,467 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1735,720,969 - 35,914,392 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2740,906,665 - 40,952,914 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LRFN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11731,569,027 - 31,760,252 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1731,680,934 - 31,763,037 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604440,394,513 - 40,587,572 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000024272   ⟹   ENSHGLP00000024053
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475418,169,513 - 18,201,639 (+)Ensembl
RefSeq Acc Id: XM_004846627   ⟹   XP_004846684
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475418,054,520 - 18,201,529 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004846684 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA98953 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000024053
  ENSHGLP00000055153
RefSeq Acc Id: XP_004846684   ⟸   XM_004846627
- UniProtKB: G5APJ3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000024053   ⟸   ENSHGLT00000024272


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000017144 Ensembl, ENTREZGENE
  ENSHGLG00000032699 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000024272 ENTREZGENE
  ENSHGLT00000071608 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRFN UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
KEGG Report hgl:101722867 UniProtKB/TrEMBL
NCBI Gene Lrfn2 ENTREZGENE
PANTHER LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  SYNAPTIC ADHESION-LIKE MOLECULE SALM UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  LRR UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
UniProt G5APJ3 ENTREZGENE, UniProtKB/TrEMBL