Frmd8 (FERM domain containing 8) - Rat Genome Database

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Gene: Frmd8 (FERM domain containing 8) Heterocephalus glaber
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Symbol: Frmd8
Name: FERM domain containing 8
RGD ID: 18928675
Description: INVOLVED IN protein localization to plasma membrane (ortholog); ASSOCIATED WITH Aicardi-Goutieres Syndrome 3 (ortholog); Bardet-Biedl syndrome (ortholog); glycogen storage disease V (ortholog); FOUND IN centriolar satellite (inferred); cytoskeleton (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FERM domain-containing protein 8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476720,983,658 - 21,002,673 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476720,983,658 - 21,003,522 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Frmd8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476720,983,658 - 21,002,673 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476720,983,658 - 21,003,522 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
FRMD8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,368,026 - 65,413,525 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1165,386,621 - 65,413,525 (+)EnsemblGRCh38hg38GRCh38
GRCh371165,154,108 - 65,180,996 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361164,910,617 - 64,937,572 (+)NCBINCBI36Build 36hg18NCBI36
Celera1162,480,396 - 62,507,341 (+)NCBICelera
Cytogenetic Map11q13.1NCBI
HuRef1161,480,989 - 61,508,193 (+)NCBIHuRef
CHM1_11165,038,043 - 65,064,995 (+)NCBICHM1_1
T2T-CHM13v2.01165,361,332 - 65,419,838 (+)NCBIT2T-CHM13v2.0
Frmd8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39195,901,002 - 5,925,297 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl195,899,730 - 5,925,302 (-)EnsemblGRCm39 Ensembl
GRCm38195,850,974 - 5,875,269 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl195,849,702 - 5,875,274 (-)EnsemblGRCm38mm10GRCm38
MGSCv37195,850,974 - 5,875,208 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36195,850,974 - 5,875,208 (-)NCBIMGSCv36mm8
Celera195,721,028 - 5,745,270 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.34NCBI
Frmd8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81212,572,534 - 212,593,181 (-)NCBIGRCr8
mRatBN7.21203,143,216 - 203,163,868 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1203,143,218 - 203,163,870 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1211,496,825 - 211,517,393 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,588,603 - 218,609,221 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,279,653 - 211,300,266 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01221,213,312 - 221,233,967 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1221,213,312 - 221,233,962 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01228,146,286 - 228,166,933 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41208,489,337 - 208,509,947 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11208,642,790 - 208,663,400 (-)NCBI
Celera1200,678,507 - 200,699,117 (-)NCBICelera
Cytogenetic Map1q43NCBI
Frmd8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542219,828,177 - 19,848,758 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542219,830,211 - 19,848,653 (-)NCBIChiLan1.0ChiLan1.0
FRMD8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2966,620,949 - 66,648,180 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11167,663,629 - 67,690,845 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01160,750,470 - 60,777,690 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11164,086,746 - 64,114,373 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1164,087,206 - 64,114,367 (+)Ensemblpanpan1.1panPan2
FRMD8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11851,782,664 - 51,807,343 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1851,784,413 - 51,806,874 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1850,390,215 - 50,414,893 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01852,823,568 - 52,848,669 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1852,823,570 - 52,848,549 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11851,919,273 - 51,944,359 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01851,492,361 - 51,517,441 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01852,287,703 - 52,311,673 (-)NCBIUU_Cfam_GSD_1.0
Frmd8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049477,576,834 - 7,591,007 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365994,014,355 - 4,032,866 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365994,019,651 - 4,033,352 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FRMD8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl26,822,967 - 6,843,470 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.126,822,964 - 6,843,941 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.225,955,716 - 5,976,840 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FRMD8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.118,824,966 - 8,853,292 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl18,827,122 - 8,852,792 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038106,124,108 - 106,150,187 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000026593   ⟹   ENSHGLP00000026358
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476720,983,658 - 21,002,673 (-)Ensembl
RefSeq Acc Id: XM_004852402   ⟹   XP_004852459
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476720,983,658 - 21,003,522 (-)NCBI
RefSeq Acc Id: XM_021264597   ⟹   XP_021120256
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476720,983,658 - 21,003,147 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004852459 (Get FASTA)   NCBI Sequence Viewer  
  XP_021120256 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB04884 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000026358
  ENSHGLP00100023377
GenBank Protein JAO01982 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004852459   ⟸   XM_004852402
- Peptide Label: isoform X1
- UniProtKB: G5B6K7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021120256   ⟸   XM_021264597
- Peptide Label: isoform X2
Ensembl Acc Id: ENSHGLP00000026358   ⟸   ENSHGLT00000026593


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018755 Ensembl, ENTREZGENE
  ENSHGLG00100017181 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000026593 ENTREZGENE
  ENSHGLT00100023618 UniProtKB/TrEMBL
Gene3D-CATH 1.20.80.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro Band_41_domain UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_sf UniProtKB/TrEMBL
  FERM_2 UniProtKB/TrEMBL
  FERM_central UniProtKB/TrEMBL
  FERM_domain UniProtKB/TrEMBL
  FERM_domain_containing UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
KEGG Report hgl:101722795 UniProtKB/TrEMBL
NCBI Gene Frmd8 ENTREZGENE
PANTHER FERM DOMAIN-CONTAINING PROTEIN 8 UniProtKB/TrEMBL
  KREV INTERACTION TRAPPED 1-RELATED UniProtKB/TrEMBL
Pfam FERM_M UniProtKB/TrEMBL
PROSITE FERM_3 UniProtKB/TrEMBL
SMART B41 UniProtKB/TrEMBL
Superfamily-SCOP SSF47031 UniProtKB/TrEMBL
UniProt A0AAX6TEG6_HETGA UniProtKB/TrEMBL
  G5B6K7 ENTREZGENE, UniProtKB/TrEMBL