Blmh (bleomycin hydrolase) - Rat Genome Database

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Gene: Blmh (bleomycin hydrolase) Heterocephalus glaber
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Symbol: Blmh
Name: bleomycin hydrolase
RGD ID: 18926600
Description: ENCODES a protein that exhibits identical protein binding (ortholog); peptidase activity (ortholog); INVOLVED IN response to toxic substance (ortholog); response to xenobiotic stimulus (ortholog); ASSOCIATED WITH Alzheimer's disease 1 (ortholog); neurofibromatosis 1 (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247862,720,383 - 2,761,968 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247862,721,314 - 2,761,792 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Blmh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247862,720,383 - 2,761,968 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247862,721,314 - 2,761,792 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
BLMH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381730,248,203 - 30,291,944 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1730,248,203 - 30,292,056 (-)EnsemblGRCh38hg38GRCh38
GRCh371728,575,221 - 28,618,962 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361725,599,349 - 25,643,200 (-)NCBINCBI36Build 36hg18NCBI36
Build 341725,599,348 - 25,643,200NCBI
Celera1725,436,850 - 25,480,700 (-)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1724,785,419 - 24,829,363 (-)NCBIHuRef
CHM1_11728,637,660 - 28,681,631 (-)NCBICHM1_1
T2T-CHM13v2.01731,192,754 - 31,236,495 (-)NCBIT2T-CHM13v2.0
Blmh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391176,836,482 - 76,878,215 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1176,815,635 - 76,878,205 (+)EnsemblGRCm39 Ensembl
GRCm381176,945,656 - 76,987,389 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1176,924,809 - 76,987,379 (+)EnsemblGRCm38mm10GRCm38
MGSCv371176,759,158 - 76,800,891 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361176,761,953 - 76,803,571 (+)NCBIMGSCv36mm8
Celera1184,444,123 - 84,485,800 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.16NCBI
Blmh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81062,270,170 - 62,313,349 (+)NCBIGRCr8
mRatBN7.21061,772,112 - 61,815,212 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1061,758,478 - 61,815,212 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1066,417,953 - 66,461,028 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01065,923,429 - 65,966,505 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01061,393,522 - 61,436,607 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01063,197,367 - 63,240,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1063,197,364 - 63,240,332 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01062,896,489 - 62,939,897 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41067,195,276 - 67,238,359 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11067,208,898 - 67,251,929 (-)NCBI
Celera1060,779,382 - 60,822,405 (+)NCBICelera
Cytogenetic Map10q24NCBI
Blmh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554813,031,114 - 3,078,678 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554813,031,283 - 3,078,678 (+)NCBIChiLan1.0ChiLan1.0
BLMH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21934,157,250 - 34,201,170 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11736,037,952 - 36,081,750 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01726,476,039 - 26,519,782 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11726,994,714 - 27,038,131 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1726,993,361 - 27,038,131 (+)Ensemblpanpan1.1panPan2
BLMH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1944,271,662 - 44,319,814 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl944,272,385 - 44,319,769 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha943,423,819 - 43,471,312 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0945,090,438 - 45,137,925 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl945,089,735 - 45,137,892 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1943,871,246 - 43,918,711 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0944,158,070 - 44,205,301 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0944,242,563 - 44,290,059 (-)NCBIUU_Cfam_GSD_1.0
Blmh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560243,374,061 - 43,420,308 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365386,250,575 - 6,298,373 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365386,251,602 - 6,298,281 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BLMH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1246,342,503 - 46,393,484 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11246,342,502 - 46,393,642 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21248,149,958 - 48,173,257 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BLMH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11623,980,736 - 24,026,126 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1623,980,712 - 24,025,976 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660756,039,024 - 6,085,399 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000014903   ⟹   ENSHGLP00000014758
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247862,720,383 - 2,761,968 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000014904   ⟹   ENSHGLP00000014759
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247862,720,383 - 2,761,968 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000014905   ⟹   ENSHGLP00000014760
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247862,720,383 - 2,761,968 (-)Ensembl
RefSeq Acc Id: XM_004857083   ⟹   XP_004857140
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247862,721,314 - 2,761,792 (-)NCBI
RefSeq Acc Id: XM_021238182   ⟹   XP_021093841
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247862,721,314 - 2,761,792 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004857140 (Get FASTA)   NCBI Sequence Viewer  
  XP_021093841 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB13344 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000014759
  ENSHGLP00100025373
GenBank Protein JAO01259 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004857140   ⟸   XM_004857083
- Peptide Label: isoform X2
- UniProtKB: G5BVP9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021093841   ⟸   XM_021238182
- Peptide Label: isoform X1
- UniProtKB: A0AAX6RAC6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000014758   ⟸   ENSHGLT00000014903
Ensembl Acc Id: ENSHGLP00000014760   ⟸   ENSHGLT00000014905
Ensembl Acc Id: ENSHGLP00000014759   ⟸   ENSHGLT00000014904


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010548 Ensembl, ENTREZGENE
  ENSHGLG00100018612 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000014904 ENTREZGENE
  ENSHGLT00100025632 UniProtKB/TrEMBL
Gene3D-CATH Cysteine proteinases UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Pept_cys_AS UniProtKB/TrEMBL
  Peptidase_C1B UniProtKB/TrEMBL
KEGG Report hgl:101706417 UniProtKB/TrEMBL
NCBI Gene Blmh ENTREZGENE
PANTHER BLEOMYCIN HYDROLASE UniProtKB/TrEMBL
  PTHR10363 UniProtKB/TrEMBL
Pfam Peptidase_C1_2 UniProtKB/TrEMBL
PIRSF PepC UniProtKB/TrEMBL
PROSITE THIOL_PROTEASE_CYS UniProtKB/TrEMBL
Superfamily-SCOP SSF54001 UniProtKB/TrEMBL
UniProt A0AAX6RAC6 ENTREZGENE, UniProtKB/TrEMBL
  G5BVP9 ENTREZGENE, UniProtKB/TrEMBL