Pfdn5 (prefoldin subunit 5) - Rat Genome Database

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Gene: Pfdn5 (prefoldin subunit 5) Heterocephalus glaber
Analyze
Symbol: Pfdn5
Name: prefoldin subunit 5
RGD ID: 18926341
Description: ENCODES a protein that exhibits amyloid-beta binding (ortholog); INVOLVED IN negative regulation of amyloid fibril formation (ortholog); negative regulation of canonical Wnt signaling pathway (ortholog); negative regulation of DNA-templated transcription (ortholog); FOUND IN cytosol (ortholog); intermediate filament cytoskeleton (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: prefoldin subunit 5 isoform alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,332,579 - 1,337,795 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249041,332,518 - 1,336,266 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pfdn5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,332,579 - 1,337,795 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249041,332,518 - 1,336,266 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PFDN5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381253,295,542 - 53,299,450 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1253,295,291 - 53,299,452 (+)EnsemblGRCh38hg38GRCh38
GRCh371253,689,326 - 53,693,234 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361251,975,502 - 51,979,501 (+)NCBINCBI36Build 36hg18NCBI36
Build 341251,975,583 - 51,979,499NCBI
Celera1253,338,519 - 53,342,520 (+)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1250,730,741 - 50,734,757 (+)NCBIHuRef
CHM1_11253,655,676 - 53,659,674 (+)NCBICHM1_1
T2T-CHM13v2.01253,261,253 - 53,265,162 (+)NCBIT2T-CHM13v2.0
Pfdn5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915102,234,551 - 102,239,925 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15102,234,551 - 102,240,308 (+)EnsemblGRCm39 Ensembl
GRCm3815102,326,116 - 102,331,490 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,326,116 - 102,331,873 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715102,156,547 - 102,161,921 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615102,154,207 - 102,159,524 (+)NCBIMGSCv36mm8
Celera15104,483,173 - 104,488,550 (+)NCBICelera
Cytogenetic Map15F2NCBI
cM Map1557.48NCBI
Pfdn5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,330,364 - 135,335,102 (+)NCBIGRCr8
mRatBN7.27133,451,778 - 133,456,516 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,451,453 - 133,456,516 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7135,212,778 - 135,217,515 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,442,158 - 137,446,895 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,427,322 - 137,432,043 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07143,924,662 - 143,929,400 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7143,924,662 - 143,929,397 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,720,703 - 141,725,442 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47141,075,469 - 141,080,207 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17141,151,896 - 141,156,640 (+)NCBI
Celera7129,885,186 - 129,889,924 (+)NCBICelera
Cytogenetic Map7q36NCBI
Pfdn5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955458555,971 - 559,927 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955458555,971 - 559,927 (+)NCBIChiLan1.0ChiLan1.0
PFDN5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21040,886,410 - 40,890,398 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11240,883,175 - 40,887,118 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01235,454,680 - 35,458,667 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11236,235,552 - 36,239,706 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,235,552 - 36,239,706 (-)Ensemblpanpan1.1panPan2
PFDN5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,906,133 - 1,909,613 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,906,133 - 1,909,613 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2744,339,679 - 44,343,149 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0271,910,594 - 1,914,080 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl271,910,594 - 1,914,080 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,928,914 - 1,932,377 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,913,828 - 1,917,308 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02744,740,367 - 44,743,847 (+)NCBIUU_Cfam_GSD_1.0
Pfdn5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494562,581,355 - 62,585,151 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651210,579,635 - 10,599,554 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651210,579,657 - 10,583,477 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PFDN5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,407,855 - 49,410,680 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1149,407,761 - 49,411,598 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037196,651,830 - 196,656,242 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000003229   ⟹   ENSHGLP00000003174
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046249041,332,579 - 1,337,795 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000003230   ⟹   ENSHGLP00000003175
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046249041,332,617 - 1,336,034 (+)Ensembl
RefSeq Acc Id: XM_004872731   ⟹   XP_004872788
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249041,332,518 - 1,336,266 (+)NCBI
RefSeq Acc Id: XM_021250612   ⟹   XP_021106271
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249041,332,518 - 1,335,240 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004872788 (Get FASTA)   NCBI Sequence Viewer  
  XP_021106271 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB09077 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000003174
  ENSHGLP00100057898
GenBank Protein JAN96821 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004872788   ⟸   XM_004872731
- Peptide Label: isoform X1
- UniProtKB: G5BIG6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106271   ⟸   XM_021250612
- Peptide Label: isoform X2
- UniProtKB: A0AAX6SA27 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000003175   ⟸   ENSHGLT00000003230
Ensembl Acc Id: ENSHGLP00000003174   ⟸   ENSHGLT00000003229


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000002363 Ensembl, ENTREZGENE
  ENSHGLG00100037119 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000003229 ENTREZGENE
  ENSHGLT00100076512 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.370 UniProtKB/TrEMBL
InterPro PFD_alpha_archaea UniProtKB/TrEMBL
  Prefoldin UniProtKB/TrEMBL
  Prefoldin_subunit_alpha UniProtKB/TrEMBL
KEGG Report hgl:101723617 UniProtKB/TrEMBL
NCBI Gene Pfdn5 ENTREZGENE
PANTHER PREFOLDIN SUBUNIT 5 UniProtKB/TrEMBL
  PTHR12674 UniProtKB/TrEMBL
Pfam Prefoldin UniProtKB/TrEMBL
Superfamily-SCOP Prefoldin UniProtKB/TrEMBL
UniProt A0AAX6SA27 ENTREZGENE, UniProtKB/TrEMBL
  G5BIG6 ENTREZGENE, UniProtKB/TrEMBL