Cpa2 (carboxypeptidase A2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Cpa2 (carboxypeptidase A2) Heterocephalus glaber
Analyze
Symbol: Cpa2
Name: carboxypeptidase A2
RGD ID: 18924743
Description: ENCODES a protein that exhibits carboxypeptidase activity (inferred); metal ion binding (inferred); metallocarboxypeptidase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH Hypoxia (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247836,001,929 - 6,024,389 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247836,001,911 - 6,024,389 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cpa2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247836,001,929 - 6,024,389 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247836,001,911 - 6,024,389 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CPA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387130,266,863 - 130,289,798 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7130,266,863 - 130,289,798 (+)EnsemblGRCh38hg38GRCh38
GRCh377129,906,703 - 129,929,638 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367129,693,960 - 129,716,871 (+)NCBINCBI36Build 36hg18NCBI36
Build 347129,500,674 - 129,523,586NCBI
Celera7124,702,462 - 124,725,405 (+)NCBICelera
Cytogenetic Map7q32.2NCBI
HuRef7124,269,090 - 124,292,037 (+)NCBIHuRef
CHM1_17129,840,284 - 129,863,099 (+)NCBICHM1_1
T2T-CHM13v2.07131,580,250 - 131,603,180 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27129,292,077 - 129,315,021 (+)NCBI
Cpa2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39630,541,641 - 30,564,475 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl630,541,581 - 30,564,475 (+)EnsemblGRCm39 Ensembl
GRCm38630,541,642 - 30,564,476 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl630,541,582 - 30,564,476 (+)EnsemblGRCm38mm10GRCm38
MGSCv37630,491,642 - 30,514,473 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36630,491,652 - 30,514,483 (+)NCBIMGSCv36mm8
Celera630,551,527 - 30,574,335 (+)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map612.52NCBI
Cpa2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8460,125,297 - 60,151,066 (+)NCBIGRCr8
mRatBN7.2459,160,357 - 59,183,677 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl459,160,357 - 59,183,674 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx464,138,256 - 64,161,826 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0460,054,438 - 60,078,012 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0458,456,358 - 58,479,936 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0457,855,416 - 57,879,239 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl457,855,416 - 57,879,239 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0457,611,439 - 57,640,155 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4457,452,111 - 57,475,357 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1457,728,244 - 57,751,439 (+)NCBI
Celera454,259,278 - 54,282,148 (+)NCBICelera
Cytogenetic Map4q22NCBI
Cpa2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547910,908,770 - 10,937,755 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547910,909,466 - 10,937,720 (+)NCBIChiLan1.0ChiLan1.0
CPA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26167,087,823 - 167,112,259 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1719,098,067 - 19,122,503 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07122,203,510 - 122,256,180 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17134,750,878 - 134,773,437 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7134,750,878 - 134,773,437 (+)Ensemblpanpan1.1panPan2
CPA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1146,645,142 - 6,665,716 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl146,562,768 - 6,665,659 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha146,331,119 - 6,351,720 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0146,405,439 - 6,426,044 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl146,405,439 - 6,425,966 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1146,610,939 - 6,631,530 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0146,355,610 - 6,376,204 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0146,499,246 - 6,519,841 (-)NCBIUU_Cfam_GSD_1.0
Cpa2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511824,843,608 - 24,881,073 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365794,976,205 - 4,995,719 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365794,976,205 - 4,995,719 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1818,557,518 - 18,577,682 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11818,557,518 - 18,581,957 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21819,545,756 - 19,577,295 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CPA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12198,896,973 - 98,920,794 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2198,898,373 - 98,920,795 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660424,483,074 - 4,505,757 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000005828   ⟹   ENSHGLP00000005755
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247836,001,929 - 6,024,389 (-)Ensembl
RefSeq Acc Id: XM_004856333   ⟹   XP_004856390
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247836,001,911 - 6,024,389 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004856390 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB08638 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000005755
  ENSHGLP00100007642
GenBank Protein JAN99369 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004856390   ⟸   XM_004856333
- UniProtKB: G5BH77 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000005755   ⟸   ENSHGLT00000005828


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004207 Ensembl, ENTREZGENE
  ENSHGLG00100005708 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000005828 ENTREZGENE
  ENSHGLT00100007739 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.340 UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro CPA_M14_CPD UniProtKB/TrEMBL
  M14A-like_propep UniProtKB/TrEMBL
  M14A_act_pep UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
KEGG Report hgl:101700104 UniProtKB/TrEMBL
NCBI Gene Cpa2 ENTREZGENE
PANTHER CARBOXYPEPTIDASE A2 UniProtKB/TrEMBL
  PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B UniProtKB/TrEMBL
Pfam Peptidase_M14 UniProtKB/TrEMBL
  Propep_M14 UniProtKB/TrEMBL
PRINTS CRBOXYPTASEA UniProtKB/TrEMBL
PROSITE CARBOXYPEPT_ZN_1 UniProtKB/TrEMBL
  CARBOXYPEPT_ZN_2 UniProtKB/TrEMBL
SMART Zn_pept UniProtKB/TrEMBL
Superfamily-SCOP Protease propeptides/inhibitors UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt A0A0P6JFC5_HETGA UniProtKB/TrEMBL
  G5BH77 ENTREZGENE, UniProtKB/TrEMBL