Ralgapa1 (Ral GTPase activating protein catalytic subunit alpha 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Ralgapa1 (Ral GTPase activating protein catalytic subunit alpha 1) Heterocephalus glaber
Analyze
Symbol: Ralgapa1
Name: Ral GTPase activating protein catalytic subunit alpha 1 (Ensembl:Ral GTPase activating protein catalytic alpha subunit 1)
RGD ID: 18921917
Description: ENCODES a protein that exhibits protein heterodimerization activity (ortholog); INVOLVED IN activation of GTPase activity (ortholog); negative regulation of DNA-binding transcription factor activity (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); genetic disease (ortholog); long QT syndrome (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Ral GTPase activating protein catalytic alpha subunit 1; ral GTPase-activating protein subunit alpha-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248381,040,525 - 1,258,151 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248381,040,108 - 1,269,000 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ralgapa1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248381,040,525 - 1,258,151 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248381,040,108 - 1,269,000 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RALGAPA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381435,538,356 - 35,809,295 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1435,538,352 - 35,809,304 (-)EnsemblGRCh38hg38GRCh38
GRCh371436,007,562 - 36,278,501 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361435,077,309 - 35,348,183 (-)NCBINCBI36Build 36hg18NCBI36
Celera1415,871,418 - 16,142,289 (-)NCBICelera
Cytogenetic Map14q13.2NCBI
HuRef1416,121,448 - 16,392,248 (-)NCBIHuRef
CHM1_11436,007,239 - 36,278,471 (-)NCBICHM1_1
T2T-CHM13v2.01429,726,082 - 29,997,030 (-)NCBIT2T-CHM13v2.0
Ralgapa1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391255,649,673 - 55,868,522 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1255,649,681 - 55,867,952 (-)EnsemblGRCm39 Ensembl
GRCm381255,602,888 - 55,821,574 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1255,602,896 - 55,821,167 (-)EnsemblGRCm38mm10GRCm38
MGSCv371256,703,886 - 56,922,154 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361256,521,029 - 56,739,297 (-)NCBIMGSCv36mm8
Celera1256,752,528 - 56,970,531 (-)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1224.06NCBI
Ralgapa1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8678,712,554 - 78,987,486 (-)NCBIGRCr8
mRatBN7.2672,977,432 - 73,252,378 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl672,977,432 - 73,252,378 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx673,399,057 - 73,673,165 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0673,705,427 - 73,979,553 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0673,132,937 - 73,407,056 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0676,386,971 - 76,661,530 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl676,396,784 - 76,608,864 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0685,920,793 - 86,193,578 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4675,849,629 - 76,163,553 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1675,853,593 - 76,049,363 (-)NCBI
Celera671,819,235 - 72,085,407 (-)NCBICelera
Cytogenetic Map6q23NCBI
Ralgapa1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540925,337,699 - 25,583,657 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540925,336,503 - 25,582,881 (+)NCBIChiLan1.0ChiLan1.0
RALGAPA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21536,852,776 - 37,123,524 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11436,069,279 - 36,340,001 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01416,292,189 - 16,562,880 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11434,472,884 - 34,743,430 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1434,472,880 - 34,743,430 (-)Ensemblpanpan1.1panPan2
RALGAPA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1814,221,516 - 14,463,481 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl814,222,749 - 14,462,998 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha814,017,673 - 14,259,618 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0814,327,816 - 14,570,610 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl814,327,816 - 14,570,547 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1814,028,892 - 14,271,002 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0814,094,489 - 14,336,412 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0814,384,204 - 14,626,322 (-)NCBIUU_Cfam_GSD_1.0
Ralgapa1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864046,143,552 - 46,361,013 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364949,659,285 - 9,866,408 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364949,649,444 - 9,866,942 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RALGAPA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl764,141,014 - 64,372,694 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1764,140,977 - 64,372,683 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2769,115,446 - 69,174,647 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RALGAPA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12412,344,951 - 12,615,669 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2412,344,934 - 12,615,622 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660531,309,431 - 1,586,599 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_013066616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013066620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013066624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002390155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01086333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01005037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000001611   ⟹   ENSHGLP00000001567
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248381,040,525 - 1,258,151 (+)Ensembl
RefSeq Acc Id: XM_013066616   ⟹   XP_012922070
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248381,040,108 - 1,269,000 (+)NCBI
RefSeq Acc Id: XM_013066620   ⟹   XP_012922074
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248381,040,108 - 1,269,000 (+)NCBI
RefSeq Acc Id: XM_013066624   ⟹   XP_012922078
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248381,040,108 - 1,269,000 (+)NCBI
RefSeq Acc Id: XM_021246566   ⟹   XP_021102225
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248381,040,108 - 1,269,000 (+)NCBI
RefSeq Acc Id: XM_021246567   ⟹   XP_021102226
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248381,040,108 - 1,269,000 (+)NCBI
RefSeq Acc Id: XM_021246569   ⟹   XP_021102228
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248381,040,108 - 1,269,000 (+)NCBI
RefSeq Acc Id: XM_021246570   ⟹   XP_021102229
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248381,040,108 - 1,269,000 (+)NCBI
RefSeq Acc Id: XM_021246571   ⟹   XP_021102230
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248381,040,108 - 1,269,000 (+)NCBI
RefSeq Acc Id: XM_021246572   ⟹   XP_021102231
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248381,040,108 - 1,269,000 (+)NCBI
RefSeq Acc Id: XM_021246573   ⟹   XP_021102232
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248381,040,108 - 1,265,521 (+)NCBI
RefSeq Acc Id: XR_002390155
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248381,040,108 - 1,234,640 (+)NCBI
RefSeq Acc Id: XP_021102231   ⟸   XM_021246572
- Peptide Label: isoform X5
- UniProtKB: A0AAX6S0D4 (UniProtKB/TrEMBL),   G5B120 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102230   ⟸   XM_021246571
- Peptide Label: isoform X5
- UniProtKB: A0AAX6S0D4 (UniProtKB/TrEMBL),   G5B120 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102228   ⟸   XM_021246569
- Peptide Label: isoform X3
- UniProtKB: A0AAX6RZP2 (UniProtKB/TrEMBL),   G5B120 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102225   ⟸   XM_021246566
- Peptide Label: isoform X1
- UniProtKB: A0AAX6RZ44 (UniProtKB/TrEMBL),   G5B120 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102226   ⟸   XM_021246567
- Peptide Label: isoform X2
- UniProtKB: A0AAX6RZP3 (UniProtKB/TrEMBL),   G5B120 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012922070   ⟸   XM_013066616
- Peptide Label: isoform X6
- UniProtKB: A0AAX6QNB7 (UniProtKB/TrEMBL),   A0A0P6J507 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102229   ⟸   XM_021246570
- Peptide Label: isoform X4
- UniProtKB: A0AAX6S056 (UniProtKB/TrEMBL),   G5B120 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012922074   ⟸   XM_013066620
- Peptide Label: isoform X7
- UniProtKB: A0AAX6QN49 (UniProtKB/TrEMBL),   A0A0P6J507 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012922078   ⟸   XM_013066624
- Peptide Label: isoform X8
- UniProtKB: A0AAX6QNZ7 (UniProtKB/TrEMBL),   A0A0P6J507 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102232   ⟸   XM_021246573
- Peptide Label: isoform X5
- UniProtKB: A0AAX6S0D4 (UniProtKB/TrEMBL),   G5B120 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000001567   ⟸   ENSHGLT00000001611


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001193 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000001611 ENTREZGENE
Gene3D-CATH 3.40.50.11210 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  Rap/Ran-GAP_sf UniProtKB/TrEMBL
  Rap/Ran_GAP_dom UniProtKB/TrEMBL
  RGPA/RALGAPB_N UniProtKB/TrEMBL
  Tuberin/Ral-act_asu UniProtKB/TrEMBL
NCBI Gene Ralgapa1 ENTREZGENE
PANTHER PTHR10063 UniProtKB/TrEMBL
  RAL GTPASE-ACTIVATING PROTEIN SUBUNIT ALPHA-1 UniProtKB/TrEMBL
Pfam RALGAPB_N UniProtKB/TrEMBL
  Rap_GAP UniProtKB/TrEMBL
PROSITE RAPGAP UniProtKB/TrEMBL
Superfamily-SCOP SSF111347 UniProtKB/TrEMBL
  SSF48371 UniProtKB/TrEMBL
UniProt A0A0P6J507 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QN49 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QNB7 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QNZ7 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RZ44 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RZP2 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RZP3 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6S056 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6S0D4 ENTREZGENE, UniProtKB/TrEMBL
  G5B120 ENTREZGENE, UniProtKB/TrEMBL