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Gene: Dglucy (D-glutamate cyclase) Heterocephalus glaber

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Symbol:

Dglucy

Name:

D-glutamate cyclase

RGD ID:

18921367

Description:

ENCODES a protein that exhibits D-glutamate cyclase activity (ortholog); INVOLVED IN glutamate metabolic process (ortholog); ASSOCIATED WITH achondrogenesis type IA (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

chromosome unknown C14orf159 homolog; CUNH14orf159; UPF0317 protein C14orf159 homolog, mitochondrial

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DGLUCY (D-glutamate cyclase)	NCBI	Ortholog
Mus musculus (house mouse):	Dglucy (D-glutamate cyclase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Dglucy (D-glutamate cyclase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Dglucy (D-glutamate cyclase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DGLUCY (D-glutamate cyclase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DGLUCY (D-glutamate cyclase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dglucy (D-glutamate cyclase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DGLUCY (D-glutamate cyclase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DGLUCY (D-glutamate cyclase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	11,375,180 - 11,422,068 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	11,374,116 - 11,423,840 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

achondrogenesis type IA (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

glutamate metabolic process (ISO)

Cellular Component

mitochondrial matrix (ISO)

mitochondrion (ISO)

Molecular Function

D-glutamate cyclase activity (ISO)

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Dglucy
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	11,375,180 - 11,422,068 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	11,374,116 - 11,423,840 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

DGLUCY
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	91,060,333 - 91,225,632 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	91,060,333 - 91,225,632 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	91,526,677 - 91,691,976 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	90,650,110 - 90,761,456 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	90,650,796 - 90,761,449	NCBI
Celera	14	71,628,800 - 71,740,164 (+)	NCBI		Celera
Cytogenetic Map	14	q32.11	NCBI
HuRef	14	71,755,884 - 71,867,994 (+)	NCBI		HuRef
CHM1_1	14	91,518,036 - 91,629,476 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	85,285,776 - 85,451,130 (+)	NCBI		T2T-CHM13v2.0

Dglucy
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	100,745,316 - 100,838,869 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	100,745,316 - 100,863,240 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	100,779,057 - 100,872,610 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	100,779,057 - 100,896,981 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	102,017,333 - 102,110,820 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	101,180,173 - 101,273,660 (+)	NCBI		MGSCv36	mm8
Celera	12	102,000,867 - 102,099,543 (+)	NCBI		Celera
Cytogenetic Map	12	E	NCBI
cM Map	12	51.1	NCBI

Dglucy
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	125,785,075 - 125,860,496 (+)	NCBI		GRCr8
mRatBN7.2	6	120,055,480 - 120,130,910 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	120,055,460 - 120,130,910 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	120,210,396 - 120,285,801 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	120,507,084 - 120,582,488 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	119,841,929 - 119,917,335 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	124,786,164 - 124,870,244 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	124,786,097 - 124,872,277 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	134,008,120 - 134,091,905 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	125,052,275 - 125,128,645 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	125,056,026 - 125,132,392 (+)	NCBI
Celera	6	117,584,344 - 117,659,179 (+)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

Dglucy
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955438	13,489,999 - 13,545,523 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955438	13,440,883 - 13,554,969 (+)	NCBI	ChiLan1.0	ChiLan1.0

DGLUCY
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	92,202,444 - 92,375,368 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	91,418,952 - 91,591,876 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	71,678,891 - 71,851,806 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	91,028,449 - 91,199,043 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	91,089,132 - 91,199,043 (+)	Ensembl	panpan1.1		panPan2

DGLUCY
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	62,052,747 - 62,086,097 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	61,631,162 - 61,665,971 (+)	NCBI		Dog10K_Boxer_Tasha

Dglucy
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	13,815,171 - 13,867,425 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936488	18,201,543 - 18,253,261 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DGLUCY
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	7	112,753,719 - 112,862,247 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	119,327,027 - 119,437,443 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DGLUCY
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	68,822,051 - 68,990,267 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666053	56,081,237 - 56,244,612 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021248244	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AHKG01009288	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AHKG01009289	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSHGLT00000013548 ⟹ ENSHGLP00000013408

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla_female_1.0 Ensembl	NW_004624734	11,375,180 - 11,422,068 (-)	Ensembl

Ensembl Acc Id:

ENSHGLT00000013549 ⟹ ENSHGLP00000013409

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla_female_1.0 Ensembl	NW_004624734	11,389,603 - 11,422,068 (-)	Ensembl

RefSeq Acc Id:

XM_021248244 ⟹ XP_021103903

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624734	11,374,116 - 11,423,840 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_021103903	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_021103903 ⟸ XM_021248244

Ensembl Acc Id:

ENSHGLP00000013409 ⟸ ENSHGLT00000013549

Ensembl Acc Id:

ENSHGLP00000013408 ⟸ ENSHGLT00000013548

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSHGLG00000009588	Ensembl
NCBI Gene	Dglucy	ENTREZGENE
UniProt	A0AAX6S769_HETGA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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