Marchf3 (membrane associated ring-CH-type finger 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Marchf3 (membrane associated ring-CH-type finger 3) Heterocephalus glaber
Analyze
Symbol: Marchf3
Name: membrane associated ring-CH-type finger 3
RGD ID: 18919612
Description: ENCODES a protein that exhibits transferase activity (inferred); ubiquitin-protein transferase activity (inferred); zinc ion binding (inferred); INVOLVED IN endocytosis (inferred); protein ubiquitination (inferred); ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); Hereditary Neoplastic Syndromes (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN intracellular membrane-bounded organelle (ortholog); lysosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase MARCH3; March3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477414,617,713 - 14,779,868 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477414,617,727 - 14,785,177 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Marchf3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477414,617,713 - 14,779,868 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477414,617,727 - 14,785,177 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MARCHF3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385126,867,714 - 127,030,558 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5126,867,714 - 127,030,558 (-)EnsemblGRCh38hg38GRCh38
GRCh375126,203,406 - 126,366,250 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365126,233,448 - 126,394,149 (-)NCBINCBI36Build 36hg18NCBI36
Build 345126,233,451 - 126,394,145NCBI
Celera5122,380,313 - 122,496,109 (-)NCBICelera
Celera5122,159,285 - 122,169,983 (-)NCBICelera
Cytogenetic Map5q23.2NCBI
HuRef5121,395,093 - 121,558,096 (-)NCBIHuRef
CHM1_15125,636,218 - 125,799,295 (-)NCBICHM1_1
T2T-CHM13v2.05127,387,759 - 127,550,637 (-)NCBIT2T-CHM13v2.0
Marchf3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391856,894,788 - 57,058,587 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1856,894,788 - 57,058,620 (-)EnsemblGRCm39 Ensembl
GRCm381856,761,716 - 56,925,515 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1856,761,716 - 56,925,548 (-)EnsemblGRCm38mm10GRCm38
MGSCv371856,921,370 - 57,085,202 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361856,887,085 - 57,050,917 (-)NCBIMGSCv36mm8
Celera1858,072,257 - 58,234,974 (-)NCBICelera
Cytogenetic Map18D3NCBI
cM Map1830.92NCBI
Marchf3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81852,435,292 - 52,587,321 (-)NCBIGRCr8
mRatBN7.21850,237,218 - 50,389,343 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1850,237,230 - 50,389,150 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1852,275,435 - 52,427,394 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01852,983,421 - 53,135,430 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01850,781,310 - 50,933,263 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01851,844,980 - 51,998,017 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1851,844,976 - 52,017,734 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01851,040,240 - 51,192,614 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41852,530,738 - 52,682,742 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11852,576,234 - 52,732,476 (-)NCBI
Celera1848,380,978 - 48,530,010 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
MARCHF3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24122,182,742 - 122,331,584 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15120,318,384 - 120,471,295 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05122,271,285 - 122,436,113 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15128,040,683 - 128,204,600 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5128,040,683 - 128,090,477 (-)Ensemblpanpan1.1panPan2
MARCHF3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11116,077,215 - 16,213,730 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1116,077,660 - 16,214,300 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1114,869,615 - 15,006,170 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01116,803,162 - 16,939,976 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1116,803,598 - 16,939,933 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11115,533,109 - 15,669,853 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01115,379,487 - 15,516,652 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01115,977,029 - 16,113,816 (-)NCBIUU_Cfam_GSD_1.0
Marchf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213138,661,001 - 138,805,566 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936504237,281 - 272,747 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936504237,260 - 422,587 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MARCHF3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2129,880,661 - 130,026,419 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12129,881,051 - 130,026,380 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22135,176,978 - 135,323,536 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MARCHF3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12329,836,665 - 30,013,484 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2329,839,576 - 29,985,684 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603448,041,428 - 48,232,545 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000011540   ⟹   ENSHGLP00000011413
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477414,617,713 - 14,779,868 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000011541   ⟹   ENSHGLP00000011414
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477414,617,713 - 14,779,868 (+)Ensembl
RefSeq Acc Id: XM_004854453   ⟹   XP_004854510
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477414,617,727 - 14,785,177 (+)NCBI
RefSeq Acc Id: XM_021266247   ⟹   XP_021121906
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477414,679,222 - 14,785,177 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004854510 (Get FASTA)   NCBI Sequence Viewer  
  XP_021121906 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000011414
RefSeq Acc Id: XP_004854510   ⟸   XM_004854453
- UniProtKB: G5B0S0 (UniProtKB/TrEMBL),   A0AAX6PLJ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021121906   ⟸   XM_021266247
- UniProtKB: G5B0S0 (UniProtKB/TrEMBL),   A0AAX6PLJ7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000011413   ⟸   ENSHGLT00000011540
Ensembl Acc Id: ENSHGLP00000011414   ⟸   ENSHGLT00000011541


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000008182 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000011541 ENTREZGENE
Gene3D-CATH Zinc/RING finger domain, C3HC4 (zinc finger) UniProtKB/TrEMBL
InterPro Znf_RING UniProtKB/TrEMBL
  Znf_RING-CH UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene Marchf3 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER UniProtKB/TrEMBL
  E3 UBIQUITIN-PROTEIN LIGASE MARCHF3 UniProtKB/TrEMBL
Pfam RINGv UniProtKB/TrEMBL
PROSITE ZF_RING_2 UniProtKB/TrEMBL
  ZF_RING_CH UniProtKB/TrEMBL
SMART RINGv UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0AAX6PLJ7 ENTREZGENE, UniProtKB/TrEMBL
  G5B0S0 ENTREZGENE, UniProtKB/TrEMBL