Nkg7 (natural killer cell granule protein 7) - Rat Genome Database

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Gene: Nkg7 (natural killer cell granule protein 7) Heterocephalus glaber
Analyze
Symbol: Nkg7
Name: natural killer cell granule protein 7
RGD ID: 18919267
Description: INVOLVED IN CD4-positive, alpha-beta T cell activation (ortholog); granzyme-mediated programmed cell death signaling pathway (ortholog); natural killer cell degranulation (ortholog); ASSOCIATED WITH multiple acyl-CoA dehydrogenase deficiency (ortholog); FOUND IN cytolytic granule (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: natural killer cell group 7 sequence; Protein NKG7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248323,501,973 - 3,504,773 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248323,501,924 - 3,502,750 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Nkg7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248323,501,973 - 3,504,773 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248323,501,924 - 3,502,750 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NKG7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381951,371,620 - 51,372,654 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1951,371,606 - 51,372,701 (-)EnsemblGRCh38hg38GRCh38
GRCh371951,874,874 - 51,875,908 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361956,566,686 - 56,567,772 (-)NCBINCBI36Build 36hg18NCBI36
Build 341956,566,685 - 56,567,772NCBI
Celera1948,925,955 - 48,927,041 (-)NCBICelera
Cytogenetic Map19q13.41NCBI
HuRef1948,206,847 - 48,207,933 (-)NCBIHuRef
CHM1_11951,876,835 - 51,877,921 (-)NCBICHM1_1
T2T-CHM13v2.01954,460,261 - 54,461,295 (-)NCBIT2T-CHM13v2.0
Nkg7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39743,086,562 - 43,087,670 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl743,086,497 - 43,087,673 (+)EnsemblGRCm39 Ensembl
GRCm38743,437,138 - 43,438,246 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl743,437,073 - 43,438,249 (+)EnsemblGRCm38mm10GRCm38
MGSCv37750,692,508 - 50,693,616 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36743,305,058 - 43,306,166 (+)NCBIMGSCv36mm8
Celera738,903,800 - 38,904,909 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.25NCBI
Nkg7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81102,981,497 - 102,982,564 (+)NCBIGRCr8
mRatBN7.2193,844,748 - 93,845,975 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl193,844,902 - 93,845,983 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx199,230,257 - 99,231,324 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01107,702,931 - 107,703,998 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01100,995,511 - 100,996,578 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0198,492,873 - 98,493,940 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl198,492,828 - 98,493,978 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0199,569,678 - 99,570,745 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4193,813,123 - 93,814,190 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1193,891,233 - 93,892,299 (+)NCBI
Celera188,122,019 - 88,123,086 (+)NCBICelera
Cytogenetic Map1q22NCBI
Nkg7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555581,028,425 - 1,029,161 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555581,027,682 - 1,029,338 (+)NCBIChiLan1.0ChiLan1.0
NKG7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22057,408,922 - 57,409,958 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11959,330,407 - 59,331,538 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01948,306,714 - 48,307,961 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11957,192,778 - 57,193,882 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1957,192,788 - 57,193,882 (-)Ensemblpanpan1.1panPan2
NKG7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11105,607,558 - 105,608,870 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1105,180,162 - 105,181,513 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01106,117,006 - 106,118,357 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1106,117,043 - 106,119,057 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11105,788,654 - 105,790,005 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01105,429,503 - 105,430,854 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01106,225,044 - 106,226,395 (+)NCBIUU_Cfam_GSD_1.0
Nkg7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934923,069,735 - 23,070,976 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493737842,066 - 43,156 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493737842,083 - 43,068 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NKG7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl658,496,089 - 58,497,827 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1658,496,089 - 58,497,827 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2651,692,516 - 51,694,254 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NKG7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1644,291,219 - 44,292,338 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl644,291,134 - 44,292,310 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607324,340,409 - 24,341,501 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000012707   ⟹   ENSHGLP00000012570
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248323,501,973 - 3,504,773 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000012708   ⟹   ENSHGLP00000012571
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248323,501,988 - 3,502,727 (+)Ensembl
RefSeq Acc Id: XM_004866761   ⟹   XP_004866818
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248323,501,924 - 3,502,750 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004866818 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB11799 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000012570
  ENSHGLP00000029149
  ENSHGLP00100049671
RefSeq Acc Id: XP_004866818   ⟸   XM_004866761
- UniProtKB: G5BR88 (UniProtKB/TrEMBL),   G5BR87 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000012571   ⟸   ENSHGLT00000012708
Ensembl Acc Id: ENSHGLP00000012570   ⟸   ENSHGLT00000012707


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000008987 Ensembl, ENTREZGENE
  ENSHGLG00000047075 UniProtKB/TrEMBL
  ENSHGLG00100036216 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000012707 ENTREZGENE
  ENSHGLT00000059104 UniProtKB/TrEMBL
  ENSHGLT00100092016 UniProtKB/TrEMBL
Gene3D-CATH 1.20.140.150 UniProtKB/TrEMBL
InterPro PMP-22/EMP/MP20 UniProtKB/TrEMBL
  PMP22/EMP/MP20/Claudin UniProtKB/TrEMBL
NCBI Gene Nkg7 ENTREZGENE
PANTHER EPITHELIAL MEMBRANE PROTEIN-RELATED UniProtKB/TrEMBL
  PROTEIN NKG7 UniProtKB/TrEMBL
Pfam PMP22_Claudin UniProtKB/TrEMBL
UniProt G5BR87 ENTREZGENE, UniProtKB/TrEMBL
  G5BR88 ENTREZGENE, UniProtKB/TrEMBL