Cdc42ep1 (CDC42 effector protein 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Cdc42ep1 (CDC42 effector protein 1) Heterocephalus glaber
Analyze
Symbol: Cdc42ep1
Name: CDC42 effector protein 1
RGD ID: 18913424
Description: ENCODES a protein that exhibits small GTPase binding (inferred); INVOLVED IN Rho protein signal transduction (ortholog); ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); Emery-Dreifuss muscular dystrophy (ortholog); myoclonic dystonia 26 (ortholog); FOUND IN cytoplasm (inferred); cytoskeleton (inferred); endomembrane system (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475210,322,267 - 10,324,549 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475210,321,256 - 10,325,884 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625  


Genomics

Comparative Map Data
Cdc42ep1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475210,322,267 - 10,324,549 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475210,321,256 - 10,325,884 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CDC42EP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382237,560,480 - 37,569,405 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2237,560,480 - 37,569,405 (+)EnsemblGRCh38hg38GRCh38
GRCh372237,956,487 - 37,965,412 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,286,446 - 36,295,358 (+)NCBINCBI36Build 36hg18NCBI36
Build 342236,280,999 - 36,289,908NCBI
Celera2221,758,351 - 21,767,271 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2220,923,769 - 20,932,624 (+)NCBIHuRef
CHM1_12237,915,221 - 37,924,140 (+)NCBICHM1_1
T2T-CHM13v2.02238,021,773 - 38,030,667 (+)NCBIT2T-CHM13v2.0
Cdc42ep1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391578,726,847 - 78,735,102 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1578,726,824 - 78,735,097 (+)EnsemblGRCm39 Ensembl
GRCm381578,842,647 - 78,850,902 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1578,842,624 - 78,850,897 (+)EnsemblGRCm38mm10GRCm38
MGSCv371578,673,077 - 78,681,332 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361579,572,076 - 79,578,545 (+)NCBIMGSCv36mm8
MGSCv361578,669,902 - 78,678,157 (+)NCBIMGSCv36mm8
Cytogenetic Map15E1NCBI
cM Map1537.7NCBI
Cdc42ep1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,275,759 - 112,283,665 (+)NCBIGRCr8
mRatBN7.27110,395,287 - 110,403,203 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,395,332 - 110,403,200 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,149,772 - 112,153,352 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,373,302 - 114,376,882 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,341,654 - 114,345,256 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,063,256 - 120,071,154 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,067,379 - 120,071,440 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07120,054,419 - 120,062,287 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47116,807,762 - 116,811,364 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17116,842,093 - 116,844,627 (+)NCBI
Celera7106,734,034 - 106,737,614 (+)NCBICelera
Cytogenetic Map7q34NCBI
Cdc42ep1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541323,984,691 - 23,987,257 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541323,984,691 - 23,987,753 (+)NCBIChiLan1.0ChiLan1.0
CDC42EP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22347,421,047 - 47,429,989 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12250,109,618 - 50,118,556 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02218,478,478 - 18,487,416 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12236,312,083 - 36,319,934 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2236,316,902 - 36,319,349 (+)Ensemblpanpan1.1panPan2
CDC42EP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11027,016,415 - 27,020,700 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1027,017,077 - 27,019,582 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1026,971,038 - 26,978,828 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01027,808,320 - 27,816,110 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,808,325 - 27,816,775 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11027,530,411 - 27,538,222 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,839,099 - 27,846,878 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01028,016,611 - 28,024,405 (-)NCBIUU_Cfam_GSD_1.0
Cdc42ep1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494510,478,771 - 10,482,856 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364923,489,185 - 3,493,231 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC42EP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl510,241,691 - 10,252,986 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1510,244,625 - 10,253,430 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.257,802,458 - 7,811,225 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDC42EP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11920,264,361 - 20,274,438 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1920,264,082 - 20,276,266 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045105,551,247 - 105,560,482 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000025786   ⟹   ENSHGLP00000025560
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475210,322,267 - 10,324,549 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000025787   ⟹   ENSHGLP00000025561
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475210,322,267 - 10,324,549 (-)Ensembl
RefSeq Acc Id: XM_004845654   ⟹   XP_004845711
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475210,321,256 - 10,325,884 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004845711 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB02176 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000025560
RefSeq Acc Id: XP_004845711   ⟸   XM_004845654
- UniProtKB: G5AYX2 (UniProtKB/TrEMBL),   A0AAX6P8P9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000025561   ⟸   ENSHGLT00000025787
Ensembl Acc Id: ENSHGLP00000025560   ⟸   ENSHGLT00000025786


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018204 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000025786 ENTREZGENE
InterPro Cdc42_effect UniProtKB/TrEMBL
  Cdc42_Effector_BORG/CEP UniProtKB/TrEMBL
  CRIB_dom UniProtKB/TrEMBL
NCBI Gene Cdc42ep1 ENTREZGENE
PANTHER CDC42 EFFECTOR PROTEIN 1 UniProtKB/TrEMBL
  CDC42 EFFECTOR PROTEIN BORG UniProtKB/TrEMBL
Pfam BORG_CEP UniProtKB/TrEMBL
  PBD UniProtKB/TrEMBL
PROSITE CRIB UniProtKB/TrEMBL
SMART PBD UniProtKB/TrEMBL
UniProt A0AAX6P8P9 ENTREZGENE, UniProtKB/TrEMBL
  G5AYX2 ENTREZGENE, UniProtKB/TrEMBL