Rmc1 (regulator of MON1-CCZ1) - Rat Genome Database

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Gene: Rmc1 (regulator of MON1-CCZ1) Heterocephalus glaber
Analyze
Symbol: Rmc1
Name: regulator of MON1-CCZ1
RGD ID: 18913310
Description: INVOLVED IN regulation of autophagy (inferred); ASSOCIATED WITH intellectual disability (ortholog); Niemann-Pick disease type C1 (ortholog); FOUND IN late endosome membrane (inferred); lysosomal membrane (inferred); Mon1-Ccz1 complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: chromosome unknown C18orf8 homolog; CUNH18orf8; uncharacterized protein C18orf8; uncharacterized protein C18orf8 homolog; WD repeat domain 98; Wdr98
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247708,641,791 - 8,662,285 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247708,641,752 - 8,662,248 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rmc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247708,641,791 - 8,662,285 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247708,641,752 - 8,662,248 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RMC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381823,503,470 - 23,531,822 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1823,503,496 - 23,531,822 (+)EnsemblGRCh38hg38GRCh38
GRCh371821,083,434 - 21,111,786 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361819,337,460 - 19,365,744 (+)NCBINCBI36Build 36hg18NCBI36
Build 341819,337,470 - 19,365,740NCBI
Celera1817,899,440 - 17,927,737 (+)NCBICelera
Cytogenetic Map18q11.2NCBI
HuRef1817,938,382 - 17,966,722 (+)NCBIHuRef
CHM1_11821,010,696 - 21,039,051 (+)NCBICHM1_1
T2T-CHM13v2.01823,697,559 - 23,725,914 (+)NCBIT2T-CHM13v2.0
Rmc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391812,301,746 - 12,331,732 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1812,301,774 - 12,323,715 (+)EnsemblGRCm39 Ensembl
GRCm381812,168,689 - 12,198,675 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1812,168,717 - 12,190,658 (+)EnsemblGRCm38mm10GRCm38
MGSCv371812,327,239 - 12,348,483 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361812,312,283 - 12,333,510 (+)NCBIMGSCv36mm8
Celera1812,402,171 - 12,423,371 (+)NCBICelera
Cytogenetic Map18A1NCBI
cM Map186.15NCBI
Rmc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8183,634,604 - 3,654,519 (+)NCBIGRCr8
mRatBN7.2183,359,848 - 3,379,764 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl183,359,832 - 3,380,795 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx183,589,522 - 3,609,622 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0184,377,218 - 4,397,320 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0183,618,015 - 3,637,920 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0183,597,210 - 3,617,160 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl183,597,240 - 3,617,283 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0183,606,715 - 3,626,297 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4183,705,351 - 3,725,697 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1183,705,350 - 3,725,693 (+)NCBI
Celera183,220,174 - 3,239,604 (+)NCBICelera
Cytogenetic Map18p13NCBI
Rmc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540211,676,671 - 11,699,709 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540211,676,883 - 11,699,715 (+)NCBIChiLan1.0ChiLan1.0
RMC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21740,933,855 - 40,962,776 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11826,626,446 - 26,655,347 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01816,754,469 - 16,783,381 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11820,380,579 - 20,409,320 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1820,380,579 - 20,409,314 (+)Ensemblpanpan1.1panPan2
RMC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1764,802,506 - 64,819,383 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl764,802,557 - 64,819,510 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha764,251,180 - 64,273,532 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0764,861,779 - 64,884,381 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl764,861,786 - 64,884,460 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1764,529,664 - 64,552,019 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0764,545,293 - 64,567,879 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0764,850,132 - 64,872,098 (-)NCBIUU_Cfam_GSD_1.0
Rmc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494460,832,590 - 60,853,407 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365502,962,545 - 2,984,923 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365502,962,667 - 2,983,451 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RMC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6108,376,777 - 108,403,169 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16108,376,763 - 108,403,175 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26101,000,372 - 101,001,998 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RMC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11857,007,889 - 57,036,438 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1857,007,974 - 57,036,231 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605031,758,980 - 31,787,387 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000012912   ⟹   ENSHGLP00000012775
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247708,641,791 - 8,662,285 (-)Ensembl
RefSeq Acc Id: XM_004853151   ⟹   XP_004853208
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247708,641,752 - 8,662,248 (-)NCBI
RefSeq Acc Id: XM_013075261   ⟹   XP_012930715
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247708,641,752 - 8,662,248 (-)NCBI
RefSeq Acc Id: XM_021265150   ⟹   XP_021120809
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247708,643,042 - 8,662,248 (-)NCBI
RefSeq Acc Id: XM_021265151   ⟹   XP_021120810
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247708,642,676 - 8,662,248 (-)NCBI
RefSeq Acc Id: XR_002397711
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247708,642,866 - 8,662,248 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004853208 (Get FASTA)   NCBI Sequence Viewer  
  XP_012930715 (Get FASTA)   NCBI Sequence Viewer  
  XP_021120809 (Get FASTA)   NCBI Sequence Viewer  
  XP_021120810 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000012775
GenBank Protein JAN97784 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_012930715   ⟸   XM_013075261
- Peptide Label: isoform X2
- UniProtKB: A0A0P6J0C7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004853208   ⟸   XM_004853151
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J0C7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021120810   ⟸   XM_021265151
- Peptide Label: isoform X4
RefSeq Acc Id: XP_021120809   ⟸   XM_021265150
- Peptide Label: isoform X3
Ensembl Acc Id: ENSHGLP00000012775   ⟸   ENSHGLT00000012912


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009136 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000012912 ENTREZGENE
Gene3D-CATH YVTN repeat-like/Quinoprotein amine dehydrogenase UniProtKB/TrEMBL
InterPro RMC1 UniProtKB/TrEMBL
  RMC1_C UniProtKB/TrEMBL
  RMC1_N UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene Rmc1 ENTREZGENE
PANTHER COLON CANCER-ASSOCIATED PROTEIN MIC1 UniProtKB/TrEMBL
  REGULATOR OF MON1-CCZ1 COMPLEX UniProtKB/TrEMBL
Pfam Mic1 UniProtKB/TrEMBL
  RMC1_N UniProtKB/TrEMBL
Superfamily-SCOP WD40 repeat-like UniProtKB/TrEMBL
UniProt A0A0P6J0C7 ENTREZGENE, UniProtKB/TrEMBL