Mlana (melan-A) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Mlana (melan-A) Heterocephalus glaber
Analyze
Symbol: Mlana
Name: melan-A
RGD ID: 18912664
Description: ASSOCIATED WITH chromosome 9p deletion syndrome (ortholog); contact dermatitis (ortholog); malignant mesothelioma (ortholog); FOUND IN Golgi apparatus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Melanoma antigen recognized by T-cells 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473610,468,485 - 10,531,910 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473610,512,358 - 10,529,888 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mlana
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473610,468,485 - 10,531,910 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473610,512,358 - 10,529,888 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MLANA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3895,890,889 - 5,910,606 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl95,890,889 - 5,910,606 (+)EnsemblGRCh38hg38GRCh38
GRCh3795,890,889 - 5,910,606 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3695,880,909 - 5,899,822 (+)NCBINCBI36Build 36hg18NCBI36
Build 3495,880,908 - 5,899,822NCBI
Celera95,828,388 - 5,847,301 (+)NCBICelera
Cytogenetic Map9p24.1NCBI
HuRef95,846,729 - 5,865,643 (+)NCBIHuRef
CHM1_195,891,587 - 5,910,499 (+)NCBICHM1_1
T2T-CHM13v2.095,896,039 - 5,915,758 (+)NCBIT2T-CHM13v2.0
Mlana
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391929,674,956 - 29,685,847 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1929,675,224 - 29,686,034 (+)EnsemblGRCm39 Ensembl
GRCm381929,697,541 - 29,708,447 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1929,697,824 - 29,708,634 (+)EnsemblGRCm38mm10GRCm38
MGSCv371929,772,431 - 29,782,796 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361929,763,821 - 29,774,631 (+)NCBIMGSCv36mm8
Celera1930,473,079 - 30,483,502 (+)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1924.28NCBI
Mlana
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81236,883,075 - 236,897,693 (+)NCBIGRCr8
mRatBN7.21227,469,537 - 227,483,343 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1227,469,537 - 227,483,343 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1235,871,286 - 235,885,085 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01242,800,965 - 242,814,764 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01235,620,666 - 235,634,587 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,869,756 - 247,883,558 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,869,756 - 247,884,442 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01255,120,234 - 255,134,036 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41233,409,294 - 233,423,982 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11233,573,321 - 233,588,798 (+)NCBI
Celera1224,620,334 - 224,633,455 (+)NCBICelera
Cytogenetic Map1q52NCBI
Mlana
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554349,877,102 - 9,894,004 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554349,877,301 - 9,893,079 (+)NCBIChiLan1.0ChiLan1.0
MLANA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v211118,662,598 - 118,679,106 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan19118,666,630 - 118,685,053 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v095,711,237 - 5,729,377 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.195,892,923 - 5,910,956 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl95,892,923 - 5,910,956 (+)Ensemblpanpan1.1panPan2
MLANA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11126,838,766 - 26,913,337 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1126,900,767 - 26,913,334 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1125,668,958 - 25,680,992 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01127,692,153 - 27,767,384 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1127,753,077 - 27,767,464 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11126,467,158 - 26,479,204 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01126,287,656 - 26,299,702 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01126,954,654 - 26,966,694 (+)NCBIUU_Cfam_GSD_1.0
Mlana
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947141,998,926 - 142,066,015 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936539504,388 - 522,096 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936539504,445 - 518,702 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MLANA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1216,232,832 - 216,245,359 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11216,230,472 - 216,247,171 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21241,958,815 - 241,973,407 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MLANA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11273,595,693 - 73,613,403 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1273,595,168 - 73,613,193 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603861,978,288 - 61,996,630 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000022305   ⟹   ENSHGLP00000022094
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473610,468,485 - 10,531,910 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000022306   ⟹   ENSHGLP00000022095
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473610,512,111 - 10,531,910 (+)Ensembl
RefSeq Acc Id: XM_004838252   ⟹   XP_004838309
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473610,512,358 - 10,529,888 (+)NCBI
RefSeq Acc Id: XM_021252794   ⟹   XP_021108453
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473610,512,379 - 10,529,888 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004838309 (Get FASTA)   NCBI Sequence Viewer  
  XP_021108453 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB04983 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000022095
GenBank Protein JAO01109 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004838309   ⟸   XM_004838252
- Peptide Label: isoform X2
- UniProtKB: A0AAX6NWC1 (UniProtKB/TrEMBL),   G5B6S2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021108453   ⟸   XM_021252794
- Peptide Label: isoform X1
- UniProtKB: A0AAX6SHZ2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000022094   ⟸   ENSHGLT00000022305
Ensembl Acc Id: ENSHGLP00000022095   ⟸   ENSHGLT00000022306


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015766 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000022306 ENTREZGENE
InterPro MLANA UniProtKB/TrEMBL
NCBI Gene Mlana ENTREZGENE
PANTHER MELANOMA ANTIGEN RECOGNIZED BY T-CELLS 1 UniProtKB/TrEMBL
  PTHR15305 UniProtKB/TrEMBL
Pfam MLANA UniProtKB/TrEMBL
UniProt A0AAX6NWC1 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SHZ2 ENTREZGENE, UniProtKB/TrEMBL
  G5B6S2 ENTREZGENE, UniProtKB/TrEMBL