Chrdl2 (chordin like 2) - Rat Genome Database

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Gene: Chrdl2 (chordin like 2) Heterocephalus glaber
Analyze
Symbol: Chrdl2
Name: chordin like 2
RGD ID: 18912000
Description: ENCODES a protein that exhibits BMP binding (inferred); INVOLVED IN chondrocyte differentiation (ortholog); negative regulation of BMP signaling pathway (ortholog); ASSOCIATED WITH 3-methylglutaconic aciduria type 7b (ortholog); intellectual disability (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Chordin-like protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248172,388,601 - 2,419,939 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248172,388,583 - 2,419,841 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074  


Genomics

Comparative Map Data
Chrdl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248172,388,601 - 2,419,939 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248172,388,583 - 2,419,841 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CHRDL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381174,696,429 - 74,731,426 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1174,696,429 - 74,731,426 (-)EnsemblGRCh38hg38GRCh38
GRCh371174,407,474 - 74,442,471 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361174,085,122 - 74,119,834 (-)NCBINCBI36Build 36hg18NCBI36
Build 341174,085,122 - 74,119,834NCBI
Celera1171,714,346 - 71,749,059 (-)NCBICelera
Cytogenetic Map11q13.4NCBI
HuRef1170,703,865 - 70,738,639 (-)NCBIHuRef
CHM1_11174,291,176 - 74,325,938 (-)NCBICHM1_1
T2T-CHM13v2.01174,625,930 - 74,660,944 (-)NCBIT2T-CHM13v2.0
Chrdl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39799,655,611 - 99,683,935 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl799,655,379 - 99,683,935 (+)EnsemblGRCm39 Ensembl
GRCm387100,006,404 - 100,034,728 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7100,006,172 - 100,034,728 (+)EnsemblGRCm38mm10GRCm38
MGSCv377107,154,914 - 107,183,236 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36799,880,522 - 99,908,809 (+)NCBIMGSCv36mm8
Celera7100,338,193 - 100,366,351 (+)NCBICelera
Cytogenetic Map7E2NCBI
cM Map754.29NCBI
Chrdl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81163,755,316 - 163,782,758 (+)NCBIGRCr8
mRatBN7.21154,343,201 - 154,370,651 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1154,343,201 - 154,370,640 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1162,338,475 - 162,365,661 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01169,518,626 - 169,545,808 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01162,392,152 - 162,419,342 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01165,008,997 - 165,036,431 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1165,008,912 - 165,036,435 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01171,209,852 - 171,237,286 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41157,391,292 - 157,411,350 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11157,469,702 - 157,506,600 (+)NCBI
Celera1152,427,830 - 152,455,412 (+)NCBICelera
Cytogenetic Map1q32NCBI
Chrdl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541416,986,233 - 17,018,225 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541416,986,199 - 17,018,166 (+)NCBIChiLan1.0ChiLan1.0
CHRDL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2975,638,327 - 75,673,343 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11176,682,725 - 76,717,753 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01169,769,476 - 69,804,480 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11173,073,668 - 73,108,386 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1173,073,738 - 73,096,068 (-)Ensemblpanpan1.1panPan2
CHRDL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12123,670,257 - 23,702,788 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2123,670,238 - 23,702,788 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2123,435,388 - 23,468,628 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02123,872,828 - 23,906,078 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2123,873,135 - 23,905,423 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12123,670,373 - 23,702,947 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02123,867,269 - 23,900,502 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02123,784,833 - 23,817,435 (+)NCBIUU_Cfam_GSD_1.0
Chrdl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494762,037,810 - 62,068,426 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364983,637,439 - 3,667,599 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364983,637,476 - 3,667,922 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHRDL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl99,017,690 - 9,053,554 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.199,017,691 - 9,053,527 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2910,070,171 - 10,190,085 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHRDL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1165,939,361 - 65,973,987 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl165,939,446 - 65,973,492 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604359,842,153 - 59,876,883 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000018492   ⟹   ENSHGLP00000018308
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248172,388,601 - 2,419,939 (+)Ensembl
RefSeq Acc Id: XM_013064947   ⟹   XP_012920401
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248172,388,583 - 2,419,841 (+)NCBI
RefSeq Acc Id: XM_021243308   ⟹   XP_021098967
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248172,388,583 - 2,419,841 (+)NCBI
RefSeq Acc Id: XM_021243309   ⟹   XP_021098968
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248172,397,116 - 2,419,841 (+)NCBI
RefSeq Acc Id: XM_021243310   ⟹   XP_021098969
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248172,398,939 - 2,419,841 (+)NCBI
RefSeq Acc Id: XM_021243311   ⟹   XP_021098970
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248172,388,583 - 2,419,841 (+)NCBI
RefSeq Acc Id: XM_021243312   ⟹   XP_021098971
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248172,388,583 - 2,419,841 (+)NCBI
RefSeq Acc Id: XP_021098967   ⟸   XM_021243308
- Peptide Label: isoform X1
- UniProtKB: G5AS87 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012920401   ⟸   XM_013064947
- Peptide Label: isoform X2
- UniProtKB: A0A0N8ETZ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098970   ⟸   XM_021243311
- Peptide Label: isoform X4
RefSeq Acc Id: XP_021098971   ⟸   XM_021243312
- Peptide Label: isoform X5
RefSeq Acc Id: XP_021098968   ⟸   XM_021243309
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021098969   ⟸   XM_021243310
- Peptide Label: isoform X3
Ensembl Acc Id: ENSHGLP00000018308   ⟸   ENSHGLT00000018492


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013117 Ensembl, ENTREZGENE
  ENSHGLG00100015549 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000018492 ENTREZGENE
  ENSHGLT00100021332 UniProtKB/TrEMBL
Gene3D-CATH 6.20.200.20 UniProtKB/TrEMBL
  Complement Module, domain 1 UniProtKB/TrEMBL
InterPro CHRDL1/2 UniProtKB/TrEMBL
  CHRDL_1/2_C UniProtKB/TrEMBL
  VWF_dom UniProtKB/TrEMBL
KEGG Report hgl:101707437 UniProtKB/TrEMBL
NCBI Gene Chrdl2 ENTREZGENE
PANTHER PTHR46303 UniProtKB/TrEMBL
  PTHR46303:SF3 UniProtKB/TrEMBL
Pfam CHRDL_1_2_C UniProtKB/TrEMBL
  VWC UniProtKB/TrEMBL
PROSITE VWFC_1 UniProtKB/TrEMBL
  VWFC_2 UniProtKB/TrEMBL
SMART VWC UniProtKB/TrEMBL
Superfamily-SCOP FnI-like domain UniProtKB/TrEMBL
UniProt A0A0N8ETZ5 ENTREZGENE, UniProtKB/TrEMBL
  G5AS87 ENTREZGENE, UniProtKB/TrEMBL