Endov (endonuclease V) - Rat Genome Database

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Gene: Endov (endonuclease V) Heterocephalus glaber
Analyze
Symbol: Endov
Name: endonuclease V
RGD ID: 18911379
Description: ENCODES a protein that exhibits DNA binding (ortholog); endodeoxyribonuclease activity, producing 5'-phosphomonoesters (ortholog); magnesium ion binding (ortholog); INVOLVED IN DNA repair (inferred); ASSOCIATED WITH Moyamoya Disease 2 (ortholog); FOUND IN cytoplasmic stress granule (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248019,577,577 - 9,590,236 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248019,577,034 - 9,590,121 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
DNA repair  (IEA)

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Endov
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248019,577,577 - 9,590,236 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248019,577,034 - 9,590,121 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ENDOV
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381780,415,167 - 80,438,086 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1780,415,165 - 80,438,086 (+)EnsemblGRCh38hg38GRCh38
GRCh371778,388,967 - 78,411,886 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361776,003,562 - 76,026,476 (+)NCBINCBI36Build 36hg18NCBI36
Celera1775,017,048 - 75,040,070 (+)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1773,826,962 - 73,849,921 (+)NCBIHuRef
CHM1_11778,475,216 - 78,498,153 (+)NCBICHM1_1
T2T-CHM13v2.01781,317,021 - 81,339,980 (+)NCBIT2T-CHM13v2.0
Endov
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911119,382,173 - 119,402,291 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11119,382,173 - 119,402,263 (+)EnsemblGRCm39 Ensembl
GRCm3811119,491,322 - 119,511,465 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11119,491,347 - 119,511,437 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711119,352,661 - 119,372,779 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611119,307,790 - 119,327,523 (+)NCBIMGSCv36mm8
Celera11131,239,372 - 131,259,285 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1183.8NCBI
Endov
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810105,258,540 - 105,276,209 (+)NCBIGRCr8
mRatBN7.210104,760,059 - 104,777,732 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10104,760,137 - 104,775,969 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10109,863,430 - 109,881,049 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010109,326,464 - 109,344,083 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010104,680,714 - 104,698,332 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010108,630,723 - 108,646,679 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10108,630,823 - 108,646,677 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010108,235,115 - 108,251,031 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410108,867,383 - 108,882,929 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera10103,305,336 - 103,321,295 (+)NCBICelera
Cytogenetic Map10q32.3NCBI
Endov
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555062,483,409 - 2,495,484 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555062,483,409 - 2,495,484 (-)NCBIChiLan1.0ChiLan1.0
ENDOV
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21996,995,792 - 97,019,100 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117101,895,598 - 101,918,996 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01774,843,661 - 74,865,960 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11780,576,451 - 80,591,856 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1780,576,450 - 80,591,856 (+)Ensemblpanpan1.1panPan2
ENDOV
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.191,418,666 - 1,436,726 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl91,407,398 - 1,437,177 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha92,036,122 - 2,054,134 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.092,028,018 - 2,046,037 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl92,031,496 - 2,045,986 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.192,051,600 - 2,069,608 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.092,177,122 - 2,195,136 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.092,258,096 - 2,276,109 (-)NCBIUU_Cfam_GSD_1.0
Endov
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056022,069,560 - 2,080,792 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365944,332,208 - 4,343,068 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365944,332,225 - 4,345,743 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103243694
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11672,389,005 - 72,413,206 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1672,389,122 - 72,403,976 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607743,700,370 - 43,715,989 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000006902   ⟹   ENSHGLP00000006818
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248019,577,577 - 9,590,236 (+)Ensembl
RefSeq Acc Id: XM_004860896   ⟹   XP_004860953
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248019,577,034 - 9,590,121 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004860953 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein JAN98906 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004860953   ⟸   XM_004860896
- UniProtKB: A0A0P6J5U8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000006818   ⟸   ENSHGLT00000006902


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004976 Ensembl
Gene3D-CATH archaeoglobus fulgidus dsm 4304 superfamily UniProtKB/TrEMBL
InterPro Endonuclease-V UniProtKB/TrEMBL
NCBI Gene Endov ENTREZGENE
PANTHER ENDONUCLEASE V UniProtKB/TrEMBL
  PTHR28511 UniProtKB/TrEMBL
Pfam Endonuclease_5 UniProtKB/TrEMBL
UniProt A0A0P6J5U8 ENTREZGENE, UniProtKB/TrEMBL