Fars2 (phenylalanyl-tRNA synthetase 2, mitochondrial) - Rat Genome Database

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Gene: Fars2 (phenylalanyl-tRNA synthetase 2, mitochondrial) Heterocephalus glaber
Analyze
Symbol: Fars2
Name: phenylalanyl-tRNA synthetase 2, mitochondrial
RGD ID: 18910045
Description: ENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); ATP binding (inferred); phenylalanine-tRNA ligase activity (inferred); INVOLVED IN tRNA processing (ortholog); ASSOCIATED WITH combined oxidative phosphorylation deficiency 14 (ortholog); combined oxidative phosphorylation deficiency 19 (ortholog); Developmental Disabilities (ortholog); FOUND IN cytoplasm (inferred); mitochondrial matrix (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phenylalanine--tRNA ligase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475619,550,103 - 19,928,538 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475619,550,198 - 20,016,561 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Fars2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475619,550,103 - 19,928,538 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475619,550,198 - 20,016,561 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
FARS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3865,249,934 - 5,771,583 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl65,261,044 - 5,829,192 (+)EnsemblGRCh38hg38GRCh38
GRCh3765,261,240 - 5,771,816 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3665,206,583 - 5,716,815 (+)NCBINCBI36Build 36hg18NCBI36
Build 3465,206,725 - 5,716,815NCBI
Celera66,488,372 - 6,998,947 (+)NCBICelera
Cytogenetic Map6p25.1NCBI
HuRef65,135,999 - 5,646,422 (+)NCBIHuRef
CHM1_165,264,226 - 5,774,754 (+)NCBICHM1_1
T2T-CHM13v2.065,119,147 - 5,640,982 (+)NCBIT2T-CHM13v2.0
Fars2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391336,301,373 - 36,721,569 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1336,301,395 - 36,910,254 (+)EnsemblGRCm39 Ensembl
GRCm381336,117,428 - 36,537,595 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1336,117,412 - 36,726,280 (+)EnsemblGRCm38mm10GRCm38
MGSCv371336,209,280 - 36,629,462 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361336,124,876 - 36,545,059 (+)NCBIMGSCv36mm8
Celera1337,233,059 - 37,656,949 (+)NCBICelera
Cytogenetic Map13A3.3NCBI
cM Map1314.44NCBI
Fars2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81728,524,737 - 28,951,818 (-)NCBIGRCr8
mRatBN7.21728,319,215 - 28,746,217 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1728,319,280 - 28,746,337 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1728,172,413 - 28,606,316 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01729,775,948 - 30,209,861 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01728,156,059 - 28,582,258 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01729,006,981 - 29,438,906 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1729,006,988 - 29,438,668 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01730,910,287 - 31,335,424 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41734,595,255 - 35,048,596 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11734,598,096 - 35,051,437 (-)NCBI
Celera1727,926,270 - 28,350,728 (-)NCBICelera
Cytogenetic Map17p12NCBI
Fars2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554657,877,824 - 8,241,742 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554657,878,115 - 8,345,749 (-)NCBIChiLan1.0ChiLan1.0
FARS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2519,889,702 - 20,402,181 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1615,894,194 - 16,406,206 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v065,096,453 - 5,608,362 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.165,279,111 - 5,790,110 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl65,387,291 - 5,792,749 (+)Ensemblpanpan1.1panPan2
FARS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1355,389,694 - 5,887,911 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl355,460,664 - 5,948,574 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha355,394,516 - 5,893,227 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0355,458,863 - 5,962,520 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl355,458,887 - 6,023,559 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1355,324,623 - 5,823,834 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0355,350,375 - 5,849,465 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0356,683,189 - 7,182,810 (+)NCBIUU_Cfam_GSD_1.0
Fars2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494618,434,776 - 18,936,050 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365346,703,749 - 7,087,658 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365346,703,760 - 7,205,204 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FARS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl73,262,396 - 3,557,407 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.173,193,433 - 3,557,413 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FARS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11766,356,479 - 66,921,276 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1766,543,452 - 66,898,446 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660445,208,363 - 5,718,281 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004847745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004847746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002396033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01036707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01036708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01036709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01036710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01036711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01036712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01036713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01036714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01036715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01036716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01036717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01001660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000006077   ⟹   ENSHGLP00000006003
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475619,550,103 - 19,928,538 (-)Ensembl
RefSeq Acc Id: XM_004847745   ⟹   XP_004847802
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475619,550,198 - 20,016,530 (-)NCBI
RefSeq Acc Id: XM_004847746   ⟹   XP_004847803
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475619,550,198 - 20,016,531 (-)NCBI
RefSeq Acc Id: XM_021260702   ⟹   XP_021116361
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475619,550,198 - 20,016,532 (-)NCBI
RefSeq Acc Id: XM_021260703   ⟹   XP_021116362
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475619,550,198 - 20,016,485 (-)NCBI
RefSeq Acc Id: XM_021260704   ⟹   XP_021116363
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475619,550,198 - 20,003,452 (-)NCBI
RefSeq Acc Id: XM_021260705   ⟹   XP_021116364
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475619,550,198 - 20,016,532 (-)NCBI
RefSeq Acc Id: XM_021260706   ⟹   XP_021116365
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475619,550,198 - 20,016,532 (-)NCBI
RefSeq Acc Id: XM_021260707   ⟹   XP_021116366
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475619,550,198 - 20,016,559 (-)NCBI
RefSeq Acc Id: XM_021260708   ⟹   XP_021116367
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475619,550,198 - 20,016,393 (-)NCBI
RefSeq Acc Id: XM_021260709   ⟹   XP_021116368
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475619,550,198 - 20,016,561 (-)NCBI
RefSeq Acc Id: XM_021260710   ⟹   XP_021116369
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475619,550,198 - 20,016,389 (-)NCBI
RefSeq Acc Id: XM_021260711   ⟹   XP_021116370
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475619,550,198 - 20,016,463 (-)NCBI
RefSeq Acc Id: XM_021260712   ⟹   XP_021116371
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475619,550,198 - 20,016,468 (-)NCBI
RefSeq Acc Id: XM_021260713   ⟹   XP_021116372
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475619,631,213 - 20,016,531 (-)NCBI
RefSeq Acc Id: XM_021260714   ⟹   XP_021116373
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475619,814,032 - 20,016,532 (-)NCBI
RefSeq Acc Id: XR_002396033
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475619,550,321 - 20,016,531 (-)NCBI
RefSeq Acc Id: XP_021116368   ⟸   XM_021260709
- Peptide Label: isoform X5
- UniProtKB: A0A0P6JC86 (UniProtKB/TrEMBL),   A0AAX6T335 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021116366   ⟸   XM_021260707
- Peptide Label: isoform X5
- UniProtKB: A0A0P6JC86 (UniProtKB/TrEMBL),   A0AAX6T335 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021116364   ⟸   XM_021260705
- Peptide Label: isoform X3
- UniProtKB: A0AAX6T4L4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021116365   ⟸   XM_021260706
- Peptide Label: isoform X4
- UniProtKB: A0AAX6T972 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021116361   ⟸   XM_021260702
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JC86 (UniProtKB/TrEMBL),   A0AAX6T8X3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004847803   ⟸   XM_004847746
- Peptide Label: isoform X6
- UniProtKB: A0AAX6PB67 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004847802   ⟸   XM_004847745
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JC86 (UniProtKB/TrEMBL),   A0AAX6PBH9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021116362   ⟸   XM_021260703
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JC86 (UniProtKB/TrEMBL),   A0AAX6T8X3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021116371   ⟸   XM_021260712
- Peptide Label: isoform X5
- UniProtKB: A0A0P6JC86 (UniProtKB/TrEMBL),   A0AAX6T335 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021116370   ⟸   XM_021260711
- Peptide Label: isoform X5
- UniProtKB: A0A0P6JC86 (UniProtKB/TrEMBL),   A0AAX6T335 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021116367   ⟸   XM_021260708
- Peptide Label: isoform X5
- UniProtKB: A0A0P6JC86 (UniProtKB/TrEMBL),   A0AAX6T335 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021116369   ⟸   XM_021260710
- Peptide Label: isoform X5
- UniProtKB: A0A0P6JC86 (UniProtKB/TrEMBL),   A0AAX6T335 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021116363   ⟸   XM_021260704
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JC86 (UniProtKB/TrEMBL),   A0AAX6T8X3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021116372   ⟸   XM_021260713
- Peptide Label: isoform X7
- UniProtKB: G5BAS5 (UniProtKB/TrEMBL),   A0AAX6T329 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021116373   ⟸   XM_021260714
- Peptide Label: isoform X8
- UniProtKB: A0AAX6T604 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000006003   ⟸   ENSHGLT00000006077


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004389 Ensembl, ENTREZGENE
  ENSHGLG00100010315 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000006077 ENTREZGENE
  ENSHGLT00100045222 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.380 UniProtKB/TrEMBL
InterPro aa-tRNA-synth_II UniProtKB/TrEMBL
  aa-tRNA-synth_II/BPL/LPL UniProtKB/TrEMBL
  Fdx_antiC-bd UniProtKB/TrEMBL
  Fdx_antiC-bd_sf UniProtKB/TrEMBL
  Phe-tRNA-synth_IIc_mito UniProtKB/TrEMBL
  Phenylalanyl-tRNA_Synthase UniProtKB/TrEMBL
NCBI Gene Fars2 ENTREZGENE
PANTHER PHENYLALANYL-TRNA SYNTHETASE UniProtKB/TrEMBL
  PTHR11538:SF41 UniProtKB/TrEMBL
Pfam FDX-ACB UniProtKB/TrEMBL
  tRNA-synt_2d UniProtKB/TrEMBL
PROSITE AA_TRNA_LIGASE_II UniProtKB/TrEMBL
  FDX_ACB UniProtKB/TrEMBL
SMART FDX-ACB UniProtKB/TrEMBL
Superfamily-SCOP SSF54991 UniProtKB/TrEMBL
  SSF55681 UniProtKB/TrEMBL
UniProt A0A0P6JC86 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PB67 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PBH9 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6T329 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6T335 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6T4L4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6T604 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6T8X3 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6T972 ENTREZGENE, UniProtKB/TrEMBL
  G5BAS5 ENTREZGENE, UniProtKB/TrEMBL