Papln (papilin, proteoglycan like sulfated glycoprotein) - Rat Genome Database

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Gene: Papln (papilin, proteoglycan like sulfated glycoprotein) Heterocephalus glaber
Analyze
Symbol: Papln
Name: papilin, proteoglycan like sulfated glycoprotein
RGD ID: 18909719
Description: ENCODES a protein that exhibits metalloendopeptidase activity (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN extracellular matrix organization (inferred); proteolysis (inferred); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN basement membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: papilin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473428,145,501 - 28,171,720 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473428,142,603 - 28,174,734 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Papln
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473428,145,501 - 28,171,720 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473428,142,603 - 28,174,734 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PAPLN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381473,235,805 - 73,274,623 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1473,237,497 - 73,274,640 (+)EnsemblGRCh38hg38GRCh38
GRCh371473,704,214 - 73,741,331 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361472,773,958 - 72,811,101 (+)NCBINCBI36Build 36hg18NCBI36
Build 341472,774,007 - 72,811,098NCBI
Celera1453,767,437 - 53,804,568 (+)NCBICelera
Cytogenetic Map14q24.2NCBI
HuRef1453,869,715 - 53,906,838 (+)NCBIHuRef
CHM1_11473,643,340 - 73,680,637 (+)NCBICHM1_1
T2T-CHM13v2.01467,441,298 - 67,480,056 (+)NCBIT2T-CHM13v2.0
Papln
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391283,809,769 - 83,841,914 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1283,810,408 - 83,839,156 (+)EnsemblGRCm39 Ensembl
GRCm381283,762,994 - 83,795,140 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1283,763,634 - 83,792,382 (+)EnsemblGRCm38mm10GRCm38
MGSCv371285,104,591 - 85,133,332 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361284,653,409 - 84,682,100 (+)NCBIMGSCv36mm8
Celera1285,210,131 - 85,238,942 (+)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1238.87NCBI
Papln
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86109,129,268 - 109,163,300 (+)NCBIGRCr8
mRatBN7.26103,398,166 - 103,432,199 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6103,398,838 - 103,432,206 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.06107,245,573 - 107,282,256 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6107,245,820 - 107,276,755 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06118,263,779 - 118,296,813 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46107,805,057 - 107,835,170 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16107,806,932 - 107,838,313 (+)NCBI
Celera6101,226,540 - 101,260,943 (+)NCBICelera
Cytogenetic Map6q31NCBI
Papln
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555232,077,856 - 2,104,134 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555232,077,496 - 2,104,826 (-)NCBIChiLan1.0ChiLan1.0
PAPLN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21574,349,212 - 74,384,378 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11473,565,748 - 73,601,330 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01453,816,437 - 53,853,704 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11472,679,834 - 72,713,975 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1472,679,910 - 72,712,009 (+)Ensemblpanpan1.1panPan2
PAPLN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1846,587,197 - 46,620,381 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl846,592,854 - 46,618,612 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha846,270,959 - 46,305,564 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0846,814,295 - 46,848,892 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl846,814,304 - 46,847,124 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1846,482,075 - 46,516,718 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0846,497,872 - 46,532,426 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0846,889,042 - 46,923,682 (+)NCBIUU_Cfam_GSD_1.0
Papln
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864029,489,519 - 29,519,995 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364882,558,289 - 2,577,942 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364882,558,007 - 2,578,173 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PAPLN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl796,598,584 - 96,625,052 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1796,584,894 - 96,622,487 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27102,378,692 - 102,417,426 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PAPLN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12450,479,932 - 50,528,284 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2450,493,117 - 50,526,322 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605338,673,708 - 38,713,980 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000019022   ⟹   ENSHGLP00000018834
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473428,145,501 - 28,171,720 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000019023   ⟹   ENSHGLP00000018835
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473428,145,501 - 28,171,522 (-)Ensembl
RefSeq Acc Id: XM_013067376   ⟹   XP_012922830
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473428,142,603 - 28,173,746 (-)NCBI
RefSeq Acc Id: XM_013067382   ⟹   XP_012922836
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473428,142,603 - 28,173,746 (-)NCBI
RefSeq Acc Id: XM_013067384   ⟹   XP_012922838
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473428,142,603 - 28,173,746 (-)NCBI
RefSeq Acc Id: XM_013067389   ⟹   XP_012922843
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473428,142,603 - 28,173,746 (-)NCBI
RefSeq Acc Id: XM_013067390   ⟹   XP_012922844
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473428,145,584 - 28,173,747 (-)NCBI
RefSeq Acc Id: XM_013067393   ⟹   XP_012922847
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473428,142,603 - 28,173,746 (-)NCBI
RefSeq Acc Id: XM_021246668   ⟹   XP_021102327
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473428,142,603 - 28,174,734 (-)NCBI
RefSeq Acc Id: XM_021246674   ⟹   XP_021102333
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473428,142,603 - 28,173,680 (-)NCBI
RefSeq Acc Id: XM_021246682   ⟹   XP_021102341
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473428,142,603 - 28,173,746 (-)NCBI
RefSeq Acc Id: XM_021246689   ⟹   XP_021102348
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473428,142,603 - 28,173,747 (-)NCBI
RefSeq Acc Id: XM_021246700   ⟹   XP_021102359
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473428,142,603 - 28,173,746 (-)NCBI
RefSeq Acc Id: XP_021102327   ⟸   XM_021246668
- Peptide Label: isoform X1
- UniProtKB: A0AAX6QNL6 (UniProtKB/TrEMBL),   A0A0P6J6Q1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102348   ⟸   XM_021246689
- Peptide Label: isoform X3
- UniProtKB: A0AAX6S010 (UniProtKB/TrEMBL),   A0A0P6J6Q1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012922847   ⟸   XM_013067393
- Peptide Label: isoform X9
- UniProtKB: A0AAX6QKL3 (UniProtKB/TrEMBL),   A0A0P6J6Q1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012922843   ⟸   XM_013067389
- Peptide Label: isoform X6
- UniProtKB: A0AAX6QPF9 (UniProtKB/TrEMBL),   A0A0P6J6Q1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102359   ⟸   XM_021246700
- Peptide Label: isoform X7
- UniProtKB: A0AAX6S1P9 (UniProtKB/TrEMBL),   A0A0P6J6Q1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012922838   ⟸   XM_013067384
- Peptide Label: isoform X5
- UniProtKB: A0AAX6QPJ5 (UniProtKB/TrEMBL),   A0A0P6J6Q1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012922836   ⟸   XM_013067382
- Peptide Label: isoform X4
- UniProtKB: A0AAX6QL73 (UniProtKB/TrEMBL),   A0A0P6J6Q1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102341   ⟸   XM_021246682
- Peptide Label: isoform X2
- UniProtKB: A0AAX6RYM6 (UniProtKB/TrEMBL),   A0A0P6J6Q1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012922830   ⟸   XM_013067376
- Peptide Label: isoform X1
- UniProtKB: A0AAX6QNL6 (UniProtKB/TrEMBL),   A0A0P6J6Q1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102333   ⟸   XM_021246674
- Peptide Label: isoform X1
- UniProtKB: A0AAX6QNL6 (UniProtKB/TrEMBL),   A0A0P6J6Q1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012922844   ⟸   XM_013067390
- Peptide Label: isoform X8
- UniProtKB: A0AAX6QPA3 (UniProtKB/TrEMBL),   A0A0P6J6Q1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000018834   ⟸   ENSHGLT00000019022
Ensembl Acc Id: ENSHGLP00000018835   ⟸   ENSHGLT00000019023


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013495 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000019023 ENTREZGENE
Gene3D-CATH 2.20.100.10 UniProtKB/TrEMBL
  2.60.120.830 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  4.10.410.10 UniProtKB/TrEMBL
InterPro ADAM_spacer1 UniProtKB/TrEMBL
  ADAMTS/ADAMTS-like UniProtKB/TrEMBL
  ADAMTS_ADAMTS-like UniProtKB/TrEMBL
  ADAMTS_CR_3 UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  Kunitz_BPTI UniProtKB/TrEMBL
  Kunitz_BPTI_sf UniProtKB/TrEMBL
  PLAC UniProtKB/TrEMBL
  Prtase_inh_Kunz-CS UniProtKB/TrEMBL
  TSP1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
NCBI Gene Papln ENTREZGENE
PANTHER ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE UniProtKB/TrEMBL
  PAPILIN UniProtKB/TrEMBL
Pfam ADAM_CR_3 UniProtKB/TrEMBL
  ADAM_spacer1 UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  Kunitz_BPTI UniProtKB/TrEMBL
  Papilin_u7 UniProtKB/TrEMBL
  PLAC UniProtKB/TrEMBL
  TSP1_ADAMTS UniProtKB/TrEMBL
  TSP_1 UniProtKB/TrEMBL
PRINTS ADAMTSFAMILY UniProtKB/TrEMBL
  BASICPTASE UniProtKB/TrEMBL
PROSITE BPTI_KUNITZ_1 UniProtKB/TrEMBL
  BPTI_KUNITZ_2 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  PLAC UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  IGv UniProtKB/TrEMBL
  SM00131 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF57362 UniProtKB/TrEMBL
  SSF82895 UniProtKB/TrEMBL
UniProt A0A0P6J6Q1 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QKL3 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QL73 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QNL6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QPA3 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QPF9 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QPJ5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RYM6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6S010 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6S1P9 ENTREZGENE, UniProtKB/TrEMBL