Itfg2 (integrin alpha FG-GAP repeat containing 2) - Rat Genome Database

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Gene: Itfg2 (integrin alpha FG-GAP repeat containing 2) Heterocephalus glaber
Analyze
Symbol: Itfg2
Name: integrin alpha FG-GAP repeat containing 2
RGD ID: 18904322
Description: INVOLVED IN germinal center B cell differentiation (ortholog); ASSOCIATED WITH Hyperphosphatemic Familial Tumoral Calcinosis 1 (ortholog); FOUND IN cytosol (inferred); Golgi apparatus (inferred); intracellular membrane-bounded organelle (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Integrin-alpha FG-GAP repeat-containing protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624860147,308 - 180,132 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624860147,476 - 175,754 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Itfg2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624860147,308 - 180,132 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624860147,476 - 175,754 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ITFG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38122,812,668 - 2,859,791 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl122,812,622 - 2,859,791 (+)EnsemblGRCh38hg38GRCh38
GRCh37122,921,834 - 2,968,957 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,792,124 - 2,804,367 (+)NCBINCBI36Build 36hg18NCBI36
Celera124,535,723 - 4,548,173 (+)NCBICelera
Cytogenetic Map12p13.33NCBI
HuRef122,779,353 - 2,791,802 (+)NCBIHuRef
CHM1_1122,921,024 - 2,933,474 (+)NCBICHM1_1
T2T-CHM13v2.0122,818,668 - 2,865,802 (+)NCBIT2T-CHM13v2.0
Itfg2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396128,386,407 - 128,401,873 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6128,386,407 - 128,401,894 (-)EnsemblGRCm39 Ensembl
GRCm386128,409,047 - 128,424,927 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6128,409,444 - 128,424,931 (-)EnsemblGRCm38mm10GRCm38
MGSCv376128,359,462 - 128,374,928 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366128,375,063 - 128,390,529 (-)NCBIMGSCv36mm8
Celera6130,086,278 - 130,101,735 (-)NCBICelera
Cytogenetic Map6F3NCBI
cM Map662.99NCBI
Itfg2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84163,371,125 - 163,384,676 (-)NCBIGRCr8
mRatBN7.24161,684,249 - 161,698,315 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4161,684,249 - 161,698,422 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4167,914,670 - 167,927,901 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04163,697,608 - 163,710,839 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04162,331,644 - 162,344,875 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04161,730,643 - 161,744,281 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4161,730,641 - 161,743,896 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04226,936,184 - 226,949,437 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44165,429,677 - 165,442,930 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14165,675,379 - 165,690,062 (-)NCBI
Celera4150,386,454 - 150,399,708 (-)NCBICelera
Cytogenetic Map4q42NCBI
Itfg2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542918,356,642 - 18,372,928 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542918,356,642 - 18,372,928 (+)NCBIChiLan1.0ChiLan1.0
ITFG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2108,362,725 - 8,392,250 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1128,359,607 - 8,389,003 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0122,933,227 - 2,980,509 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1122,865,297 - 2,889,752 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl122,865,297 - 2,877,555 (+)Ensemblpanpan1.1panPan2
ITFG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12741,933,741 - 41,944,464 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2741,934,575 - 41,944,472 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha274,739,698 - 4,750,438 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02742,291,904 - 42,302,645 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2742,291,904 - 42,302,596 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12742,233,426 - 42,244,162 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02742,203,098 - 42,213,849 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0274,099,392 - 4,110,145 (+)NCBIUU_Cfam_GSD_1.0
Itfg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945106,025,311 - 106,039,230 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366063,144,602 - 3,158,890 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366063,144,616 - 3,158,825 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITFG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl567,291,772 - 67,305,607 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1567,292,901 - 67,306,208 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2569,579,204 - 69,592,320 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ITFG2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1112,877,864 - 2,891,223 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl112,877,997 - 2,890,477 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660635,425,387 - 5,438,866 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000003993   ⟹   ENSHGLP00000003935
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624860147,308 - 180,132 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000003994   ⟹   ENSHGLP00000003936
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624860147,634 - 175,387 (+)Ensembl
RefSeq Acc Id: XM_004869324   ⟹   XP_004869381
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624860147,477 - 175,754 (+)NCBI
RefSeq Acc Id: XM_004869325   ⟹   XP_004869382
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624860147,477 - 175,754 (+)NCBI
RefSeq Acc Id: XR_002390790
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624860147,476 - 175,754 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004869381 (Get FASTA)   NCBI Sequence Viewer  
  XP_004869382 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA99828 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000003935
  ENSHGLP00000040976
  ENSHGLP00100030192
RefSeq Acc Id: XP_004869381   ⟸   XM_004869324
- Peptide Label: isoform X1
- UniProtKB: G5AS18 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004869382   ⟸   XM_004869325
- Peptide Label: isoform X2
- UniProtKB: A0AAX6QAV9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000003936   ⟸   ENSHGLT00000003994
Ensembl Acc Id: ENSHGLP00000003935   ⟸   ENSHGLT00000003993


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000002900 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLG00100005049 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000003993 ENTREZGENE
  ENSHGLT00000047991 UniProtKB/TrEMBL
  ENSHGLT00100079979 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.130 UniProtKB/TrEMBL
InterPro Integrin_alpha_N UniProtKB/TrEMBL
  KICSTOR_ITFG2 UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report hgl:101711532 UniProtKB/TrEMBL
NCBI Gene Itfg2 ENTREZGENE
PANTHER KICSTOR COMPLEX PROTEIN ITFG2 UniProtKB/TrEMBL
  PTHR16317 UniProtKB/TrEMBL
Pfam Itfg2 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
  SSF69318 UniProtKB/TrEMBL
UniProt A0AAX6QAV9 ENTREZGENE, UniProtKB/TrEMBL
  G5AS18 ENTREZGENE, UniProtKB/TrEMBL