Ppp1r12b (protein phosphatase 1 regulatory subunit 12B) - Rat Genome Database

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Gene: Ppp1r12b (protein phosphatase 1 regulatory subunit 12B) Heterocephalus glaber
Analyze
Symbol: Ppp1r12b
Name: protein phosphatase 1 regulatory subunit 12B
RGD ID: 18902620
Description: ENCODES a protein that exhibits enzyme inhibitor activity (inferred); phosphatase regulator activity (inferred); protein kinase binding (inferred); INVOLVED IN signal transduction (inferred); ASSOCIATED WITH breast lobular carcinoma (ortholog); Breast Neoplasms (ortholog); Congenital Infantile Lactic Acidosis (ortholog); FOUND IN A band (inferred); cytoplasm (inferred); stress fiber (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248078,209,547 - 8,414,511 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248078,203,118 - 8,414,121 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
A band  (IEA)
cytoplasm  (IEA)
stress fiber  (IEA)
Z disc  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ppp1r12b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248078,209,547 - 8,414,511 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248078,203,118 - 8,414,121 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PPP1R12B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381202,348,699 - 202,592,702 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1202,348,699 - 202,592,706 (+)EnsemblGRCh38hg38GRCh38
GRCh371202,317,827 - 202,561,830 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361200,584,459 - 200,824,320 (+)NCBINCBI36Build 36hg18NCBI36
Build 341199,049,492 - 199,289,354NCBI
Celera1175,441,739 - 175,684,836 (+)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1173,483,918 - 173,723,526 (+)NCBIHuRef
CHM1_11203,740,082 - 203,979,944 (+)NCBICHM1_1
T2T-CHM13v2.01201,610,813 - 201,854,508 (+)NCBIT2T-CHM13v2.0
Ppp1r12b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391134,682,396 - 134,883,699 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1134,682,396 - 134,883,680 (-)EnsemblGRCm39 Ensembl
GRCm381134,754,658 - 134,955,963 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,754,658 - 134,955,942 (-)EnsemblGRCm38mm10GRCm38
MGSCv371136,662,520 - 136,852,517 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361136,571,069 - 136,772,351 (-)NCBIMGSCv36mm8
Celera1137,390,041 - 137,584,808 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.24NCBI
Ppp1r12b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81348,751,256 - 48,948,933 (-)NCBIGRCr8
mRatBN7.21346,199,418 - 46,397,108 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1346,201,251 - 46,397,108 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1348,805,925 - 49,003,623 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01350,093,993 - 50,291,695 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01347,360,066 - 47,557,419 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01351,583,603 - 51,784,641 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1351,584,299 - 51,784,639 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01356,637,005 - 56,836,014 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41347,705,569 - 47,917,673 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11347,729,746 - 47,931,553 (-)NCBI
Celera1346,526,402 - 46,722,920 (-)NCBICelera
Cytogenetic Map13q13NCBI
Ppp1r12b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540638,405,535 - 38,629,688 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540638,405,297 - 38,636,503 (+)NCBIChiLan1.0ChiLan1.0
PPP1R12B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2146,793,994 - 47,036,171 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1146,760,651 - 46,998,751 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01177,945,674 - 178,185,871 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11182,243,497 - 182,482,216 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1182,243,497 - 182,482,216 (+)Ensemblpanpan1.1panPan2
PPP1R12B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.17512,692 - 713,848 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl7512,575 - 713,709 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha7561,883 - 766,819 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.07517,183 - 722,439 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl7517,388 - 722,447 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.17505,819 - 710,889 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.07616,770 - 819,263 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.07637,977 - 843,111 (-)NCBIUU_Cfam_GSD_1.0
Ppp1r12b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934472,757,815 - 72,973,959 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365671,992,495 - 2,208,684 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365671,992,487 - 2,208,611 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP1R12B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1024,465,041 - 24,637,358 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11024,463,900 - 24,637,361 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21028,860,843 - 28,972,139 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PPP1R12B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12526,832,411 - 27,063,528 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2526,833,355 - 27,062,870 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605527,605,675 - 27,842,303 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000010274   ⟹   ENSHGLP00000010160
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248078,209,547 - 8,414,511 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000010275   ⟹   ENSHGLP00000010161
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248078,214,545 - 8,414,511 (-)Ensembl
RefSeq Acc Id: XM_004862210   ⟹   XP_004862267
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248078,203,118 - 8,414,045 (-)NCBI
RefSeq Acc Id: XM_004862213   ⟹   XP_004862270
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248078,203,118 - 8,340,266 (-)NCBI
RefSeq Acc Id: XM_021242352   ⟹   XP_021098011
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248078,203,118 - 8,414,046 (-)NCBI
RefSeq Acc Id: XM_021242353   ⟹   XP_021098012
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248078,203,118 - 8,414,045 (-)NCBI
RefSeq Acc Id: XM_021242354   ⟹   XP_021098013
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248078,203,118 - 8,414,045 (-)NCBI
RefSeq Acc Id: XM_021242355   ⟹   XP_021098014
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248078,203,118 - 8,414,045 (-)NCBI
RefSeq Acc Id: XM_021242356   ⟹   XP_021098015
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248078,203,118 - 8,414,044 (-)NCBI
RefSeq Acc Id: XM_021242357   ⟹   XP_021098016
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248078,337,435 - 8,414,121 (-)NCBI
RefSeq Acc Id: XM_021242358   ⟹   XP_021098017
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248078,203,118 - 8,247,600 (-)NCBI
RefSeq Acc Id: XP_021098011   ⟸   XM_021242352
- Peptide Label: isoform X1
- UniProtKB: A0AAX6RMJ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004862267   ⟸   XM_004862210
- Peptide Label: isoform X5
- UniProtKB: G5B383 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098013   ⟸   XM_021242354
- Peptide Label: isoform X3
- UniProtKB: A0AAX6RMI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098012   ⟸   XM_021242353
- Peptide Label: isoform X2
- UniProtKB: A0AAX6RN10 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098014   ⟸   XM_021242355
- Peptide Label: isoform X4
- UniProtKB: A0AAX6RNH5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098015   ⟸   XM_021242356
- Peptide Label: isoform X6
- UniProtKB: A0A0P6J4A3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004862270   ⟸   XM_004862213
- Peptide Label: isoform X8
- UniProtKB: A0AAX6PY06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098017   ⟸   XM_021242358
- Peptide Label: isoform X9
- UniProtKB: A0AAX6RQJ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098016   ⟸   XM_021242357
- Peptide Label: isoform X7
- UniProtKB: A0AAX6RN33 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000010160   ⟸   ENSHGLT00000010274
Ensembl Acc Id: ENSHGLP00000010161   ⟸   ENSHGLT00000010275


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007290 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000010274 ENTREZGENE
  ENSHGLT00000010275 ENTREZGENE
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
  6.10.140.390 UniProtKB/TrEMBL
  6.10.250.1820 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  MYPT1/MYPT2/Mbs85 UniProtKB/TrEMBL
  PP1_Regulatory_Subunit UniProtKB/TrEMBL
  PRKG1_interact UniProtKB/TrEMBL
KEGG Report hgl:101711489 UniProtKB/TrEMBL
NCBI Gene Ppp1r12b ENTREZGENE
PANTHER PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 UniProtKB/TrEMBL
  PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12B UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  PRKG1_interact UniProtKB/TrEMBL
PIRSF PP1_12ABC_vert UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
UniProt A0A0P6J4A3 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PY06 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RMI1 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RMJ6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RN10 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RN33 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RNH5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RQJ7 ENTREZGENE, UniProtKB/TrEMBL
  G5B383 ENTREZGENE, UniProtKB/TrEMBL