Rabep2 (rabaptin, RAB GTPase binding effector protein 2) - Rat Genome Database

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Gene: Rabep2 (rabaptin, RAB GTPase binding effector protein 2) Heterocephalus glaber
Analyze
Symbol: Rabep2
Name: rabaptin, RAB GTPase binding effector protein 2
RGD ID: 18902204
Description: ENCODES a protein that exhibits growth factor activity (inferred); GTPase activator activity (inferred); INVOLVED IN regulation of cilium assembly (ortholog); ASSOCIATED WITH Brody myopathy (ortholog); chromosome 16p11.2 deletion syndrome, 220-kb (ortholog); chromosome 16p11.2 deletion syndrome, 593-kb (ortholog); FOUND IN ciliary basal body (ortholog); cytosol (ortholog); Golgi apparatus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Rab GTPase-binding effector protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478212,855,583 - 12,867,411 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478212,856,701 - 12,867,414 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rabep2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478212,855,583 - 12,867,411 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478212,856,701 - 12,867,414 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RABEP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381628,904,421 - 28,925,238 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1628,904,421 - 28,936,526 (-)EnsemblGRCh38hg38GRCh38
GRCh371628,915,742 - 28,936,559 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361628,823,243 - 28,844,033 (-)NCBINCBI36Build 36hg18NCBI36
Build 341628,823,243 - 28,844,033NCBI
Celera1627,872,792 - 27,913,272 (-)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1626,783,084 - 26,804,504 (-)NCBIHuRef
CHM1_11629,927,556 - 29,948,336 (-)NCBICHM1_1
T2T-CHM13v2.01629,184,915 - 29,206,347 (-)NCBIT2T-CHM13v2.0
Rabep2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397126,027,596 - 126,045,079 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7126,027,931 - 126,048,417 (+)EnsemblGRCm39 Ensembl
GRCm387126,428,423 - 126,445,907 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7126,428,759 - 126,449,245 (+)EnsemblGRCm38mm10GRCm38
MGSCv377133,572,281 - 133,589,421 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367126,220,588 - 126,237,049 (+)NCBIMGSCv36mm8
Celera7126,281,311 - 126,298,461 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.03NCBI
Rabep2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81190,433,501 - 190,457,241 (+)NCBIGRCr8
mRatBN7.21181,010,305 - 181,026,651 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,010,305 - 181,026,648 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1189,340,797 - 189,357,218 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01196,526,872 - 196,543,298 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01189,214,842 - 189,231,201 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01197,839,583 - 197,855,953 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1197,839,430 - 197,856,312 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01204,820,064 - 204,836,434 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11185,686,801 - 185,703,549 (+)NCBI
Celera1178,670,261 - 178,686,622 (+)NCBICelera
Cytogenetic Map1q36NCBI
Rabep2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554936,549,111 - 6,559,577 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554936,548,951 - 6,560,039 (+)NCBIChiLan1.0ChiLan1.0
RABEP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21831,833,943 - 31,856,798 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11636,651,472 - 36,674,320 (+)NCBINHGRI_mPanPan1
PanPan1.11629,291,023 - 29,314,177 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1629,289,949 - 29,314,177 (-)Ensemblpanpan1.1panPan2
RABEP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1618,399,992 - 18,413,537 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl618,397,161 - 18,456,477 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,978,094 - 19,991,347 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0618,535,856 - 18,549,110 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl618,535,856 - 18,548,590 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1618,335,401 - 18,348,654 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0618,249,957 - 18,263,211 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0618,566,334 - 18,579,587 (-)NCBIUU_Cfam_GSD_1.0
Rabep2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344123,709,462 - 123,720,490 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650111,806,836 - 11,817,838 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650111,807,369 - 11,818,350 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RABEP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl318,568,266 - 18,585,925 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1318,568,264 - 18,586,259 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2318,753,523 - 18,771,453 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RABEP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1526,130,667 - 26,165,415 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl526,131,512 - 26,168,514 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660683,459,735 - 3,481,196 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000020772   ⟹   ENSHGLP00000020570
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462478212,855,583 - 12,867,411 (+)Ensembl
RefSeq Acc Id: XM_004856035   ⟹   XP_004856092
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478212,856,701 - 12,867,414 (+)NCBI
RefSeq Acc Id: XM_021237393   ⟹   XP_021093052
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478212,856,701 - 12,867,414 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004856092 (Get FASTA)   NCBI Sequence Viewer  
  XP_021093052 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB11841 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000020570
RefSeq Acc Id: XP_021093052   ⟸   XM_021237393
- Peptide Label: isoform X2
- UniProtKB: G5BRD8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004856092   ⟸   XM_004856035
- Peptide Label: isoform X1
- UniProtKB: A0AAX6PPC1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000020570   ⟸   ENSHGLT00000020772


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014706 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000020772 ENTREZGENE
Gene3D-CATH 1.20.5.340 UniProtKB/TrEMBL
  Single helix bin UniProtKB/TrEMBL
InterPro Rabaptin UniProtKB/TrEMBL
  Rabaptin_coiled-coil UniProtKB/TrEMBL
  Rabaptin_Rab5-bd_dom UniProtKB/TrEMBL
NCBI Gene Rabep2 ENTREZGENE
PANTHER PTHR31179 UniProtKB/TrEMBL
  PTHR31179:SF6 UniProtKB/TrEMBL
Pfam Rab5-bind UniProtKB/TrEMBL
  Rabaptin UniProtKB/TrEMBL
PRINTS RABAPTIN UniProtKB/TrEMBL
Superfamily-SCOP G protein-binding domain UniProtKB/TrEMBL
UniProt A0AAX6PPC1 ENTREZGENE, UniProtKB/TrEMBL
  G5BRD8 ENTREZGENE, UniProtKB/TrEMBL