DNER (delta/notch like EGF repeat containing) - Rat Genome Database

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Gene: DNER (delta/notch like EGF repeat containing) Chlorocebus sabaeus
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Symbol: DNER
Name: delta/notch like EGF repeat containing
RGD ID: 18793710
Description: ENCODES a protein that exhibits calcium ion binding (inferred); Notch binding (inferred); INVOLVED IN glial cell differentiation (ortholog); Notch receptor processing (ortholog); skeletal muscle fiber development (ortholog); PARTICIPATES IN Notch signaling pathway; FOUND IN dendrite (inferred); early endosome (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: delta and Notch-like epidermal growth factor-related receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110115,357,097 - 115,739,992 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10115,357,084 - 115,739,777 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604083,717,051 - 84,079,196 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DNER
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110115,357,097 - 115,739,992 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10115,357,084 - 115,739,777 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604083,717,051 - 84,079,196 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
DNER
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382229,357,629 - 229,714,555 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2229,357,629 - 229,714,555 (-)EnsemblGRCh38hg38GRCh38
GRCh372230,222,345 - 230,579,271 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362229,930,589 - 230,287,530 (-)NCBINCBI36Build 36hg18NCBI36
Celera2223,997,841 - 224,354,753 (-)NCBICelera
Cytogenetic Map2q36.3NCBI
HuRef2222,063,233 - 222,419,423 (-)NCBIHuRef
CHM1_12230,228,171 - 230,585,124 (-)NCBICHM1_1
T2T-CHM13v2.02229,840,190 - 230,197,123 (-)NCBIT2T-CHM13v2.0
Dner
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39184,347,560 - 84,673,942 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl184,347,560 - 84,673,942 (-)EnsemblGRCm39 Ensembl
GRCm38184,369,839 - 84,696,221 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl184,369,839 - 84,696,221 (-)EnsemblGRCm38mm10GRCm38
MGSCv37184,366,414 - 84,692,796 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36184,248,864 - 84,575,246 (-)NCBIMGSCv36mm8
Celera184,429,076 - 84,756,047 (-)NCBICelera
Cytogenetic Map1C5NCBI
cM Map143.4NCBI
Dner
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8993,035,108 - 93,350,568 (-)NCBIGRCr8
mRatBN7.2985,586,985 - 85,902,461 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl985,586,987 - 85,902,637 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx994,015,224 - 94,317,755 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0999,143,722 - 99,446,238 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0997,530,682 - 97,831,070 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0991,965,866 - 92,291,172 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl991,965,866 - 92,291,220 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0991,700,319 - 92,023,695 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4983,716,070 - 83,821,294 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1983,899,837 - 84,004,713 (-)NCBI
Celera983,016,881 - 83,326,945 (-)NCBICelera
Cytogenetic Map9q35NCBI
Dner
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554535,307,256 - 5,615,609 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554535,307,256 - 5,615,550 (+)NCBIChiLan1.0ChiLan1.0
DNER
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213131,978,893 - 132,337,732 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B131,993,860 - 132,352,692 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B116,604,193 - 116,963,026 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B235,409,108 - 235,642,158 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B235,409,108 - 235,642,161 (-)Ensemblpanpan1.1panPan2
DNER
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12541,709,570 - 41,887,705 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2541,710,420 - 42,019,885 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2542,333,402 - 42,646,081 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02541,964,886 - 42,276,304 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2541,964,888 - 42,276,509 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12541,894,543 - 42,207,390 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02541,734,881 - 42,047,810 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02541,908,081 - 42,221,461 (-)NCBIUU_Cfam_GSD_1.0
Dner
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303183,901,774 - 184,204,798 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365256,735,049 - 7,037,042 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365256,734,924 - 7,037,947 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNER
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15130,415,061 - 130,754,048 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115130,414,159 - 130,754,043 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215144,454,568 - 144,601,085 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Dner
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248433,237,270 - 3,552,551 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248433,238,390 - 3,552,566 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 17 33 33 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000005084   ⟹   ENSCSAP00000003317
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl10115,357,084 - 115,739,777 (-)Ensembl
RefSeq Acc Id: XM_007966532   ⟹   XP_007964723
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.110115,357,097 - 115,739,991 (-)NCBI
Vero_WHO_p1.0NW_02366604083,717,051 - 84,079,196 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007966533   ⟹   XP_007964724
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.110115,357,097 - 115,739,992 (-)NCBI
Vero_WHO_p1.0NW_02366604083,717,051 - 84,079,196 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007964723 (Get FASTA)   NCBI Sequence Viewer  
  XP_007964724 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000003317.1
RefSeq Acc Id: XP_007964724   ⟸   XM_007966533
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007964723   ⟸   XM_007966532
- Peptide Label: isoform X1
Ensembl Acc Id: ENSCSAP00000003317   ⟸   ENSCSAT00000005084


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000007041 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000005084.1 UniProtKB/TrEMBL
Gene3D-CATH Laminin UniProtKB/TrEMBL
InterPro DNER_C UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  Fol_N UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  Notch_signaling UniProtKB/TrEMBL
NCBI Gene DNER ENTREZGENE
PANTHER DELTA AND NOTCH-LIKE EPIDERMAL GROWTH FACTOR-RELATED RECEPTOR UniProtKB/TrEMBL
  NOTCH LIGAND FAMILY MEMBER UniProtKB/TrEMBL
Pfam DNER_C UniProtKB/TrEMBL
  EGF UniProtKB/TrEMBL
PRINTS EGFBLOOD UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  FOLN UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A0D9R3X8_CHLSB UniProtKB/TrEMBL