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Gene: FITM1 (fat storage inducing transmembrane protein 1) Chlorocebus sabaeus

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Symbol:

FITM1

Name:

fat storage inducing transmembrane protein 1

RGD ID:

18777570

Description:

ENCODES a protein that exhibits coenzyme A diphosphatase activity (inferred); diacylglycerol binding (inferred); triglyceride binding (inferred); INVOLVED IN lipid droplet formation (inferred); lipid droplet organization (inferred); lipid storage (inferred); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); lysinuric protein intolerance (ortholog); Specific Granule Deficiency (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

fat storage-inducing transmembrane protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	1,116,201 - 1,118,814 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	1,117,451 - 1,119,275 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666036	12,797,952 - 12,800,552 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Brain-Lung-Thyroid Syndrome (ISO)

lysinuric protein intolerance (ISO)

Specific Granule Deficiency (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

lipid droplet formation (IEA)

lipid droplet organization (IEA)

lipid storage (IEA)

phospholipid biosynthetic process (IEA)

positive regulation of triglyceride storage (IEA)

Cellular Component

endoplasmic reticulum (IEA)

endoplasmic reticulum membrane (IEA)

membrane (IEA)

Molecular Function

coenzyme A diphosphatase activity (IEA)

diacylglycerol binding (IEA)

triglyceride binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

FITM1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	1,116,201 - 1,118,814 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	1,117,451 - 1,119,275 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666036	12,797,952 - 12,800,552 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

FITM1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	24,130,659 - 24,132,847 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	24,130,659 - 24,132,849 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	24,599,868 - 24,602,056 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	23,670,608 - 23,671,898 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	14	4,465,145 - 4,466,528 (+)	NCBI		Celera
Cytogenetic Map	14	q12	NCBI
HuRef	14	4,715,896 - 4,717,279 (+)	NCBI		HuRef
CHM1_1	14	24,599,346 - 24,600,729 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	18,328,966 - 18,331,154 (+)	NCBI		T2T-CHM13v2.0

Fitm1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	55,813,131 - 55,814,409 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	55,813,074 - 55,814,411 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	55,575,674 - 55,576,952 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	55,575,617 - 55,576,954 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	56,194,511 - 56,195,789 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	54,529,745 - 54,531,023 (+)	NCBI		MGSCv36	mm8
Celera	14	53,380,530 - 53,381,808 (+)	NCBI		Celera
Cytogenetic Map	14	C3	NCBI
cM Map	14	28.19	NCBI

Fitm1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	33,034,705 - 33,035,974 (+)	NCBI		GRCr8
mRatBN7.2	15	29,064,746 - 29,066,015 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	29,064,707 - 29,066,015 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	30,910,449 - 30,911,718 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	32,057,655 - 32,058,924 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	30,300,002 - 30,301,271 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	34,251,805 - 34,253,074 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	34,251,606 - 34,253,073 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	38,142,000 - 38,143,269 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	33,708,626 - 33,709,895 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	33,723,380 - 33,725,595 (+)	NCBI
Celera	15	28,640,667 - 28,641,936 (+)	NCBI		Celera
Cytogenetic Map	15	p13	NCBI

Fitm1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	36,267,121 - 36,268,462 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955409	36,267,121 - 36,268,462 (-)	NCBI	ChiLan1.0	ChiLan1.0

FITM1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	25,485,044 - 25,488,412 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	24,701,536 - 24,704,903 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	4,906,504 - 4,909,119 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	23,031,818 - 23,033,459 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	23,031,818 - 23,033,459 (+)	Ensembl	panpan1.1		panPan2

FITM1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	4,127,148 - 4,128,779 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	4,127,488 - 4,128,794 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	4,048,851 - 4,050,451 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	4,237,758 - 4,239,358 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	4,238,067 - 4,239,333 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	3,928,387 - 3,929,987 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	3,990,136 - 3,991,736 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	4,252,301 - 4,253,901 (+)	NCBI		UU_Cfam_GSD_1.0

Fitm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	35,974,305 - 35,978,696 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936722	410,294 - 411,679 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936722	410,294 - 411,680 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FITM1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	75,166,912 - 75,168,245 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	75,166,986 - 75,168,240 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	80,438,281 - 80,439,536 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Fitm1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624820	8,402,347 - 8,403,663 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624820	8,402,347 - 8,407,399 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in FITM1
43 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007986283	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000014276 ⟹ ENSCSAP00000012252

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	24	1,117,451 - 1,119,275 (+)	Ensembl

RefSeq Acc Id:

XM_007986283 ⟹ XP_007984474

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	24	1,116,201 - 1,118,814 (+)	NCBI
Vero_WHO_p1.0	NW_023666036	12,797,952 - 12,800,552 (+)	NCBI

Sequence:

show sequence

CTCCTGACCTCAGGCAATCTACCTGCCTCAGCCTCCCAAAGTGCTGGGATTATAGGTGTGAGCC
ACCGCGCCCGGCCTAGTTCAAAATTCTTTTATAGGGTTCATTGAAGGTCACTATTCCAAGGTAT
GGGCTTTAGGATCTGGAAAGAATCTAATTGATTATCCAATCTGTCTTGACGAATTTATAAAGGA
AATTGATTTACTGACGACTGAAGAGAGTTCATTGGTTTTCCTGAAGTCACACAGTTGGGTCCAG
AACTCGGGTGTCCTTGCTTGCTCATTCCTTCCACTACTGCCGCTGTGCTCTGAAATCCCACCAC
TGGTTTTGAGGAATGAGGAAGAAAGAAAAAGTGATCTCGAAATAGTTACTGACTAACAGGCACT
CTCTGTGGGTAGGTGGCTCTCTACCCTGCTGCTGCCGCCTCAGCAGTCAGACTGGGAGGGCAGG
CTTGCATGGAGAGCCCTGAAGTCCAGGCTAGTTGGTTGGAGGATGGAACTTCAGGTTTCAACTG
ACTCCTGTCTGGCAATTGCCCTTTTAGGGTCTCCTCTACCCCTGTCACCTGGGAGTAAACCTAA
TCTTTAGGGATCTGAGGGTCAACGTAATCAACAGATGAAACCGCCAGTTTACACAGCAGCCCTA
GACCAAACTAGTCCCTTAGAGACCCTCAATCCAGACAGGAACTAAGGCAGAGCCAAGCTGCTGG
GGTCACAGAGTGCTGAAGTGGATACCCCTGCTGATCTGCCTCCCAAGGCCTAAGGTGGCCACAG
TGCTGTGCACAGCCACCTTGTGGCAACTGCTGTTGGTAGGCTCTTGTGCTCAGAACCCCAGAAG
AAGGGCTAGGTCATACTGATGATAAGACTGACAGCTTTTTTAAAAAAACGACTTTCAAGGTTTG
GTTAGTTTTACCTTCATGACCTCTGCTTTCCCTGTGGAGCAAATGGTAAAGTAGGGGTGGGTGG
AGAGGGACTTTGGCAGACCCTGGCAGACTATGGACAAGGACAGCCCTGAACAGCTGGCCCTGAG
ACATGAACTGGAACATGGTTGGAGCCGAGGACACAGGACTAACAGGAAAGGACACAGACTGCTG
TTAGGACACATGCTACCACACACCCGAGGCCAGGACCCTGCTGACGTGGCAGACCTCCACCCTG
GCCCCTTACTGCCCCCCGCCCCTCTCCCCCGCCTGCCAGCTGCCAACAGGGCTCTGCCTTGTGT
CTGCCACACCTGTCACTGCCTATCCTTGTCCGGGGGGGCCCCATCAGCCCCTCCTCAGCTGCCC
AGCAGAGCAAGCAGCTAGTGGGGAGGGGAGGGAACATGGAGCGGGGGCCGGTGGTGGGGGCAGG
GCTGGGGGCCGGGGCCCGAATCCGGGCACTGCTGGGCTGCCTGGTCAAGGTGCTTCTCTGGGTG
GCCTCTGCCTTGCTGTACTTTGGAAGCGAACAGGCCGCCCGCCTTCTGGGCAGCCCCTGCTTAC
GGCGCCTCTACCATGCCTGGCTGGCAGCAGTGGTCATCTTTGGGCCCCTTCTGCAGTTCCATGT
CAACCCTCGGACTATCTTCGCCAGCCACGGCAACTTCTTCAACATAAAATTTGTGAATTCAGCC
TGGGGCTGGACATGCACCTTCCTAGGGGGCTTTGTGTTGCTGGTGGTGTTTCTGGCTACACGGC
GCGTGGCAGTAACTGCCAGACACCTGAGCCGACTGGTGGTGGGAGCAGCCGTGTGGCGGGGAGC
TGGCCGAGCCTTCCTGCTCATCGAGGACCTGACTGGCTCCTGCTTCGAGCCACTGCCCCACGGT
CTGCTGCTCCACGAGCTGCCTGACCGCCGCAGCTGCCTGGCGGCTGGCCACCAGTGGCGGGGCT
ACACGGTCTCCTCCCACACCTTCCTGCTCACCTTCTGCTGCCTGCTTATGGCAGAGGAAGCAGC
TGTGTTCGCCAAGTACCTGGCCCATGGGCTGCCTGCTGGCGCCCCCCTGCGCCTTGTCTTCCTG
CTGAACGTGCTGCTGCTGGGCCTCTGGAACTTCTTGCTGCTCTGTACCGTCATCTATTTCCACC
AGTACACTCACAAGGTGGTGGGTGCCGCAGTGGGCACCTTCGCCTGGTACCTCACCTATGGCAG
CTGGTATCATCAGCCCTGGTCTCCAGGGAGTCCAGGCCATGGGCTCTTCCCCCGTCCCCACTCC
AGCCGCAAGCATAACTGAAAGAAATAAAAGCCATCGGGCCTGGCTCTGGCTCCTCTCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_007984474	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000012252.1

RefSeq Acc Id:	XP_007984474 ⟸ XM_007986283
- UniProtKB:	A0A0D9RUG3 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000012252 ⟸ ENSCSAT00000014276

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000016182	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000014276.1	UniProtKB/TrEMBL
InterPro	FIT	UniProtKB/TrEMBL
	FIT1	UniProtKB/TrEMBL
	FITM1/2	UniProtKB/TrEMBL
KEGG Report	csab:103228707	UniProtKB/TrEMBL
NCBI Gene	FITM1	ENTREZGENE
PANTHER	FAT STORAGE-INDUCING TRANSMEMBRANE PROTEIN 1	UniProtKB/TrEMBL
	PTHR23129	UniProtKB/TrEMBL
UniProt	A0A0D9RUG3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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