Advanced Search (OLGA)

Gene: PMP2 (peripheral myelin protein 2) Chlorocebus sabaeus

Analyze

Symbol:

PMP2

Name:

peripheral myelin protein 2

RGD ID:

18756605

Description:

ENCODES a protein that exhibits cholesterol binding (inferred); fatty acid binding (inferred); lipid binding (inferred); INVOLVED IN membrane organization (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease type 1G (ortholog); genetic disease (ortholog); neuropathy (ortholog); FOUND IN cytoplasm (inferred); myelin sheath (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

myelin P2 protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	76,860,328 - 76,864,996 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	76,857,892 - 76,864,931 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	64,330,286 - 64,337,465 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease type 1G (ISO)

genetic disease (ISO)

neuropathy (ISO)

peripheral nervous system disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

membrane organization (IEA,ISO)

Cellular Component

cytoplasm (IEA)

myelin sheath (IEA)

Molecular Function

cholesterol binding (IEA)

fatty acid binding (IEA)

lipid binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

PMP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	76,860,328 - 76,864,996 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	76,857,892 - 76,864,931 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	64,330,286 - 64,337,465 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

PMP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	81,440,326 - 81,447,439 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	81,440,326 - 81,447,439 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	82,352,561 - 82,359,674 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	82,515,116 - 82,522,274 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	82,515,120 - 82,522,274	NCBI
Celera	8	78,357,520 - 78,364,678 (-)	NCBI		Celera
Cytogenetic Map	8	q21.13	NCBI
HuRef	8	77,842,497 - 77,849,649 (-)	NCBI		HuRef
CHM1_1	8	82,404,170 - 82,411,323 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	81,871,924 - 81,879,037 (-)	NCBI		T2T-CHM13v2.0

Pmp2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	10,244,911 - 10,248,945 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	10,244,911 - 10,248,989 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	10,179,851 - 10,183,885 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	10,179,851 - 10,183,929 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	10,179,851 - 10,183,885 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	10,162,383 - 10,166,417 (-)	NCBI		MGSCv36	mm8
Celera	3	10,210,078 - 10,214,112 (-)	NCBI		Celera
Cytogenetic Map	3	A1	NCBI
cM Map	3	2.54	NCBI

Pmp2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	93,518,730 - 93,522,648 (+)	NCBI		GRCr8
mRatBN7.2	2	91,611,334 - 91,615,252 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	91,611,334 - 91,615,252 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	98,101,602 - 98,105,530 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	96,222,589 - 96,226,517 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	91,279,441 - 91,283,369 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	93,827,504 - 93,831,419 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	93,827,504 - 93,831,419 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	113,582,541 - 113,586,456 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	93,566,284 - 93,570,202 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	87,213,211 - 87,217,129 (+)	NCBI		Celera
Cytogenetic Map	2	q23	NCBI

PMP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	97,178,197 - 97,185,370 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	72,806,025 - 72,813,195 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	77,963,094 - 77,970,272 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	79,586,548 - 79,593,748 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	79,586,553 - 79,593,863 (-)	Ensembl	panpan1.1		panPan2

LOC487015
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	29	28,619,027 - 28,625,677 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	29	28,622,033 - 28,625,586 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	29	28,900,788 - 28,904,984 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	29	28,752,765 - 28,756,957 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	29	28,753,403 - 28,757,158 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	29	28,822,971 - 28,827,162 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	29	28,836,593 - 28,840,788 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	29	29,193,424 - 29,197,615 (-)	NCBI		UU_Cfam_GSD_1.0

PMP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	55,135,340 - 55,141,624 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1 Ensembl	4	55,116,164 - 55,120,760 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	55,116,259 - 55,141,619 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	60,147,781 - 60,170,182 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Variants

Variants in PMP2
106 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
70	30	17	29	29	58	18

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008000968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000011357 ⟹ ENSCSAP00000009430

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	8	76,857,892 - 76,864,931 (-)	Ensembl

RefSeq Acc Id:

XM_008000968 ⟹ XP_007999159

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	8	76,860,328 - 76,864,996 (-)	NCBI
Vero_WHO_p1.0	NW_023666039	64,330,286 - 64,337,465 (+)	NCBI

Sequence:

show sequence

TTGGGTCTCTGTAAGAGTCACATGCTTTGGGCGTCCTTGAAAAGAATCTTCTCAGGCCTCAGCA
TCTTATCTGAGTCTCCTGAATCCCACTTAGAACTGTGTTGAGCTCTCACCCATCACGATGAGCA
ACAAATTCCTGGGCACCTGGAAACTTGTCTCTAGTGAGAACTTTGACGATTACATGAAAGCTCT
GGGTGTGGGGTTAGCCACCAGAAAACTGGGAAATTTGGCCAAACCCACTGTGATCATCAGCAAG
AAAGGAGATATTATAACTATACGAACTGAAAGCACCTTTAAAAATACAGAGATCTCCTTCAAGC
TAGGCCAGGAATTTGAAGAAACCACAGCTGACAATAGAAAGGCCAAGAGCATCGTAACCCTGCA
GAGAGGATCACTGAATCAAGTGCAGAGATGGGATGGCAAAGAGACAACCATAAAGAGAAAGCTA
GTGAATGGGAAAATGGTAGTGGAATGTAAAATGAAGGGCGTGGTGTGCACCAGAATCTATGAGA
AGGTCTGAAAAATCGTTTCCTCATTGAAGTGGCTTTCGATCATTTAATGATGGAAATCAATTGC
TTCCATTGACAAAACCTGAATACACTGCAAATGTTTGTTTTTGCTTTTGTCTTAATATATCAGA
TAGGCAAAGGCCTAAACTGAGAATTAATCTAGAAGTCAGTGTTATTTAAACAGTTTTAATGTGC
ATACGTGTTATTACTACATTAAAGCATATATATTGGCCAGACACGATCAGTTGATGATGTCATT
TAACTAATTACAAAATTCTAACCTATGTTGAACTTTGTATACTTGAAATGATAATAAAAAGGAT
AGAATTTGTTAGTAAAAGGAAATCAAGGTATTGATCATAGTAGCAAACTCAAATGCTGACAGGG
GCTGGGGAGTTATGGGGAAGGAGCATCAGAAATGAGGCAAGCTAGGAGAATGAGCTATTTTAAT
GTAAAGAATTGTAGTCTCAGCTAAAAGGGGTAGCCTCTACTCCAACCAACATTTTTAAATTAAT
GGATAATTTATAGACAATTAAATGCACAGATATTAAGGATAGAGTTCAGTCCACTGTGATAAAT
GCATGCACC

hide sequence

Protein Sequences


Protein RefSeqs	XP_007999159	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000009430
	ENSCSAP00000009430.1

RefSeq Acc Id:	XP_007999159 ⟸ XM_008000968
- UniProtKB:	A0A0D9RLE1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000009430 ⟸ ENSCSAT00000011357

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000013262	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000011357.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.128.20	UniProtKB/TrEMBL
InterPro	Calycin	UniProtKB/TrEMBL
	Fatty_acid-bd	UniProtKB/TrEMBL
	ILBP	UniProtKB/TrEMBL
	Lipocln_cytosolic_FA-bd_dom	UniProtKB/TrEMBL
	Myelin_P2	UniProtKB/TrEMBL
KEGG Report	csab:103237038	UniProtKB/TrEMBL
NCBI Gene	PMP2	ENTREZGENE
PANTHER	PTHR11955	UniProtKB/TrEMBL
	PTHR11955:SF64	UniProtKB/TrEMBL
Pfam	Lipocalin	UniProtKB/TrEMBL
PRINTS	FATTYACIDBP	UniProtKB/TrEMBL
PROSITE	FABP	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50814	UniProtKB/TrEMBL
UniProt	A0A0D9RLE1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM