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Gene: LALBA (lactalbumin alpha) Chlorocebus sabaeus

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Symbol:

LALBA

Name:

lactalbumin alpha

RGD ID:

18689329

Description:

ENCODES a protein that exhibits enzyme-substrate adaptor activity (ortholog); INVOLVED IN defense response to Gram-negative bacterium (inferred); defense response to Gram-positive bacterium (inferred); lactose biosynthetic process (inferred); PARTICIPATES IN Glut1 deficiency syndrome pathway; lactose biosynthetic pathway; ASSOCIATED WITH colon cancer (ortholog); gastroenteritis (ortholog); FOUND IN protein-containing complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

alpha-lactalbumin

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LALBA (lactalbumin alpha)	NCBI	Ortholog
Mus musculus (house mouse):	Lalba (lactalbumin, alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Lalba (lactalbumin, alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Lalba (lactalbumin alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LALBA (lactalbumin alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LALBA (lactalbumin alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Lalba (lactalbumin alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LALBA (lactalbumin alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Lalba (lactalbumin alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Lalba (lactalbumin alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mChlSab1.0.hap1	11	46,275,913 - 46,280,079 (-)	NCBI		mChlSab1.0.hap1
Vero_WHO_p1.0	NW_023666037	201,328,409 - 201,332,576 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0
ChlSab1.1	11	44,816,340 - 44,819,407 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	44,816,613 - 44,818,673 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

colon cancer (ISO)

gastroenteritis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

defense response to Gram-negative bacterium (IEA)

defense response to Gram-positive bacterium (IEA)

lactose biosynthetic process (IEA)

Cellular Component

extracellular region (IEA)

protein-containing complex (ISO)

Molecular Function

calcium ion binding (IEA)

enzyme-substrate adaptor activity (ISO)

lactose synthase activity (IEA)

lysozyme activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

Glut1 deficiency syndrome pathway (ISO)

lactose biosynthetic pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

LALBA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mChlSab1.0.hap1	11	46,275,913 - 46,280,079 (-)	NCBI		mChlSab1.0.hap1
Vero_WHO_p1.0	NW_023666037	201,328,409 - 201,332,576 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0
ChlSab1.1	11	44,816,340 - 44,819,407 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	44,816,613 - 44,818,673 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM

LALBA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	48,567,684 - 48,571,845 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	48,567,684 - 48,571,865 (-)	Ensembl		GRCh38.p14 Ensembl	hg38	GRCh38
GRCh37	12	48,961,467 - 48,965,628 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	47,247,734 - 47,250,096 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	47,247,734 - 47,250,096	NCBI
Celera	12	47,757,465 - 47,759,827 (-)	NCBI		Celera
Cytogenetic Map	12	q13.11	NCBI
HuRef	12	45,995,555 - 45,997,917 (-)	NCBI		HuRef
CHM1_1	12	48,927,287 - 48,929,649 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	48,529,699 - 48,533,867 (-)	NCBI		T2T-CHM13v2.0

Lalba
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	98,378,281 - 98,380,827 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	98,378,281 - 98,380,602 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	98,480,400 - 98,482,934 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	98,480,400 - 98,482,721 (-)	Ensembl		GRCm38.p6 Ensembl	mm10	GRCm38
MGSCv37	15	98,310,831 - 98,313,114 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	98,308,434 - 98,310,717 (-)	NCBI		MGSCv36	mm8
Celera	15	100,627,451 - 100,629,779 (-)	NCBI		Celera
Cytogenetic Map	15	F1	NCBI
cM Map	15	54.48	NCBI

Lalba
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	131,504,572 - 131,520,707 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	131,504,572 - 131,507,072 (-)	Ensembl				GRCr8
mRatBN7.2	7	129,625,531 - 129,628,034 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	129,625,535 - 129,628,061 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	131,432,976 - 131,435,228 (-)	NCBI	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	133,658,521 - 133,660,776 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	133,571,012 - 133,573,264 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	7	133,587,436 - 133,589,921 (-)	NCBI
Lyon_Normotensive	7	134,538,713 - 134,541,198 (-)	NCBI
Lyon_Hypertensive	7	134,666,241 - 134,668,726 (-)	NCBI
F344_StmMcwi	7	133,110,927 - 133,113,412 (-)	NCBI
Rnor_6.0	7	140,088,420 - 140,096,347 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	140,088,421 - 140,090,922 (-)	Ensembl		Rnor_6.0 Ensembl	rn6	Rnor6.0
Rnor_5.0	7	139,231,203 - 139,233,459 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	137,220,916 - 137,223,614 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	126,117,233 - 126,119,018 (-)	NCBI		Celera
RGSC_v3.1	7	137,297,352 - 137,300,051 (-)	NCBI
Cytogenetic Map	7	q36	NCBI

Lalba
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955500	7,487,603 - 7,489,573 (-)	Ensembl		ChiLan1.0 Ensembl
ChiLan1.0	NW_004955500	7,487,603 - 7,489,573 (-)	NCBI	ChiLan1.0	ChiLan1.0

LALBA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	45,610,745 - 45,615,180 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	45,607,661 - 45,611,941 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	40,178,422 - 40,180,897 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	41,055,189 - 41,057,565 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	41,055,189 - 41,057,565 (+)	Ensembl		PanPan1.1 Ensembl	panPan2	panpan1.1

LALBA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	5,898,674 - 5,900,688 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	5,874,879 - 5,900,686 (+)	Ensembl		CanFam3.1 Ensembl	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	40,357,753 - 40,359,766 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	5,949,754 - 5,951,770 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	5,949,754 - 5,951,768 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	5,912,583 - 5,914,594 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	5,903,319 - 5,905,335 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	40,749,445 - 40,751,461 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Lalba
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mIctTri1.hap1	6	65,926,830 - 65,928,815 (+)	NCBI		mIctTri1.hap1
HiC_Itri_2	NW_024404945	66,682,105 - 66,684,110 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936512	6,480,955 - 6,482,725 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936512	6,480,955 - 6,482,725 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LALBA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	79,214,505 - 79,216,791 (-)	Ensembl		Sscrofa11.1 Ensembl	susScr11	Sscrofa11.1
Sscrofa11.1	5	79,214,487 - 79,216,791 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	82,539,971 - 82,542,274 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Lalba
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624816	3,546,727 - 3,549,589 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2
HetGla_female_1.0 Ensembl	NW_004624816	3,547,540 - 3,549,441 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl

Lalba
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	271,295,927 - 271,298,391 (-)	NCBI	Rrattus_CSIRO_v1	Rrattus_CSIRO_v1

Variants

Variants in LALBA
61 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

hemolymphoid system	mesenchyme	mesoderm
17	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008003064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JBLKOC010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000004298 ⟹ ENSCSAP00000002555

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	11	44,816,613 - 44,818,673 (-)	Ensembl

RefSeq Acc Id:

XM_008003064 ⟹ XP_008001255

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
mChlSab1.0.hap1	11	46,275,913 - 46,280,079 (-)	NCBI
Vero_WHO_p1.0	NW_023666037	201,328,409 - 201,332,576 (+)	NCBI
ChlSab1.1	11	44,816,340 - 44,819,407 (-)	NCBI

Sequence:

show sequence

TCAAGTGATCCACCAGCCTCAGCCTCCCAAAGTGTTGGGGTTACAGGTGTGAGACATTGTGCCT
GGCCTAGACGCTTTCATACAGGCTTTTCAGTTATGCATTTTCCTTAAGTAGGAAGTCTTAGGAT
CCAAGTTATATCTGATTGTTGTAGTCTACATTCCCATATTCTATTTCTGTTTCTGAGCCTTCAG
TCATGAGCTCAGAACTCATTCTGGGCTTTGTTACATGGCTGGGTTGGTTGGACAAGTGCCAGCT
TTGATCCTGGGACTGCGGCATGCGATGACATACACCCCCTCTCCACATTCTGTGTGTCTCTACG
GGGGAGGGGGAAGCTGGCCATAGAACTTTATTGTATTTTCTGATTCCTCACTTATATTGCCCCC
ATGGCCTTCATTGTTCCTAAAGTAACCAGAGACAGTGCTTCCTAGAACCAACCCTACAAAAAAC
AAAGGGATAAACAAAGCCAAATGGGAAGCTGGATCAAGGTTTGAACTCTTTCTGGGCAGAGAAC
AATACCTGGTATGGACTAGATACTGGGAGAGGGAAAGGAAAAGTAGGGTGAATTACAGAAGGAA
GCTGGCAGGCTCAGTGTTTCTGTCTTGGCATGACCAGTCTCTCTTCATTCTCTTCCTAGTTGTA
GGGCTTGGTGCCAGAGCCCCTGAGGCTTTCTGCATGAATATAAAGAAATGAAACTGAGTGATGC
TTCCATTTCAGGTTCTTGGGGGCCGCCAAAATGAGGTCGTTTGTCCCTCTGTTCCTGGTGGGCA
TCCTGTTCCCTGCCATCCCGGCCAAGCAATTTACAAAATGTGAGCTGTCCCAGCTGCTGAAAGA
CATAGATGGTTATGGAGGCATCGCTTTGCCTGAATTCATCTGTACCATGTTTCACACCAGTGGT
TATGACACACAAGCCATAGTTGAAAGCAATGGAAGCACAGAATATGGACTCTTCCAGATCAGTA
ATAAGCTTTGGTGCAAGAGCAGCCAGGTCCCTCAGTCAAGGAATATCTGCGACATCTCCTGTGA
CAAGTTCCTGGACGATGACATTACTGATGACATAATGTGTGCCAAGAAGATCCTGGATATTAAA
GGAATTGACTACTGGTTGGCCCATAAAGCCCTCTGCACTGAGAAGCTGGAACAGTGGCTTTGTG
AGAAGTTGTGAGCATCTGCTGTCCTTGGCATCCCTGCCCACTCCACATTCCTGGAATGCCTCTT
TCCTAATGCCACCTCAGTTTGCTTCTTTCTGTTTCCCCAAAGCTTATCTGTCTCTGAGCCTTGG
GCGCTGTAGTGACATCACTGAACTCTTGAGGACTGTTTTCCGGAAATGCCTGAGTGGTGCACTG
AGCTCTAGACCCTTGCTCAGTGCCCCCGATGGCACTTTCACTACAGCACAGATTTCACTTCTGT
CTTGAATAAAGATCCCAATTTGAAGTCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008001255	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000002555.1

RefSeq Acc Id:

XP_008001255 ⟸ XM_008003064

Ensembl Acc Id:

ENSCSAP00000002555 ⟸ ENSCSAT00000004298

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000006263	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000004298.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.530.10	UniProtKB/TrEMBL
InterPro	Glyco_hydro_22	UniProtKB/TrEMBL
	Glyco_hydro_22_CS	UniProtKB/TrEMBL
	Lactalbumin	UniProtKB/TrEMBL
	Lysozyme-like_dom_sf	UniProtKB/TrEMBL
KEGG Report	csab:103238238	UniProtKB/TrEMBL
NCBI Gene	LALBA	ENTREZGENE
PANTHER	PTHR11407	UniProtKB/TrEMBL
	PTHR11407:SF32	UniProtKB/TrEMBL
Pfam	Lys	UniProtKB/TrEMBL
PRINTS	LACTALBUMIN	UniProtKB/TrEMBL
	LYZLACT	UniProtKB/TrEMBL
PROSITE	GLYCOSYL_HYDROL_F22_1	UniProtKB/TrEMBL
	GLYCOSYL_HYDROL_F22_2	UniProtKB/TrEMBL
SMART	LYZ1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53955	UniProtKB/TrEMBL
UniProt	A0A0D9R1R6_CHLSB	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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