OTOA (otoancorin) - Rat Genome Database

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Advanced Search (OLGA)
Gene: OTOA (otoancorin) Chlorocebus sabaeus
Analyze
Symbol: OTOA
Name: otoancorin
RGD ID: 18676392
Description: INVOLVED IN cell-matrix adhesion (inferred); multicellular organism growth (inferred); sensory perception of sound (inferred); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 22 (ortholog); autosomal recessive nonsyndromic deafness 7 (ortholog); FOUND IN apical plasma membrane (inferred); cell surface (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1520,184,525 - 20,278,438 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl520,198,412 - 20,278,433 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660689,587,651 - 9,667,862 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
OTOAGreen Monkeyautosomal recessive nonsyndromic deafness  ISOOTOA (Homo sapiens)8554872ClinVar Annotator: match by term: Deafness and autosomal recessiveClinVarPMID:23173898 more ...
OTOAGreen Monkeyautosomal recessive nonsyndromic deafness 22  ISOOTOA (Homo sapiens)8554872ClinVar more ...ClinVarPMID:11972037 more ...
OTOAGreen Monkeyautosomal recessive nonsyndromic deafness 7  ISOOTOA (Homo sapiens)8554872ClinVar Annotator: match by term: Deafness and autosomal recessive 7ClinVarPMID:35802133 and PMID:36633841
OTOAGreen Monkeyautosomal recessive nonsyndromic deafness 9  ISOOTOA (Homo sapiens)8554872ClinVar Annotator: match by term: Deafness and autosomal recessive 9ClinVarPMID:25741868
OTOAGreen Monkeygenetic disease  ISOOTOA (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:24033266 more ...
OTOAGreen MonkeyHearing Loss  ISOOTOA (Homo sapiens)8554872ClinVar more ...ClinVarPMID:23173898 more ...
OTOAGreen MonkeyNonsyndromic Sensorineural Hearing Loss  ISOOTOA (Homo sapiens)8554872ClinVar Annotator: match by term: nonsyndromic sensorineural hearing lossClinVarPMID:25741868
OTOAGreen MonkeyUsher syndrome  ISOOTOA (Homo sapiens)8554872ClinVar Annotator: match by term: Usher syndromeClinVarPMID:23173898 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
OTOAGreen Monkeyautosomal recessive nonsyndromic deafness 22  ISOOTOA (Homo sapiens)7240710 OMIM 


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
OTOAGreen Monkeycell-matrix adhesion acts_upstream_of_or_withinIEAUniProtKB:Q8K561 and ensembl:ENSMUSP00000044177150520179 EnsemblGO_REF:0000107
OTOAGreen Monkeycell-matrix adhesion involved_inIEAPANTHER:PTN000601826150520179 TreeGrafterGO_REF:0000118
OTOAGreen Monkeymulticellular organism growth acts_upstream_of_or_withinIEAUniProtKB:Q8K561 and ensembl:ENSMUSP00000044177150520179 EnsemblGO_REF:0000107
OTOAGreen Monkeysensory perception of sound acts_upstream_of_or_withinIEAUniProtKB:Q8K561 and ensembl:ENSMUSP00000044177150520179 EnsemblGO_REF:0000107
OTOAGreen Monkeytransmission of nerve impulse acts_upstream_of_or_withinIEAUniProtKB:Q8K561 and ensembl:ENSMUSP00000044177150520179 EnsemblGO_REF:0000107

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
OTOAGreen Monkeyapical plasma membrane located_inIEAUniProtKB:Q8K561 and ensembl:ENSMUSP00000044177150520179 EnsemblGO_REF:0000107
OTOAGreen Monkeycell surface located_inIEAPANTHER:PTN000601826150520179 TreeGrafterGO_REF:0000118

PMID:30032202  



OTOA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1520,184,525 - 20,278,438 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl520,198,412 - 20,278,433 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660689,587,651 - 9,667,862 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
OTOA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381621,663,968 - 21,760,729 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1621,663,968 - 21,761,935 (+)EnsemblGRCh38hg38GRCh38
GRCh371621,675,289 - 21,772,050 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361621,597,336 - 21,679,551 (+)NCBINCBI36Build 36hg18NCBI36
Build 341621,623,784 - 21,679,550NCBI
Celera1621,371,583 - 21,424,019 (+)NCBICelera
Cytogenetic Map16p12.2NCBI
HuRef1620,071,671 - 20,153,825 (+)NCBIHuRef
CHM1_11622,692,724 - 22,774,996 (+)NCBICHM1_1
T2T-CHM13v2.01622,456,214 - 22,552,969 (-)NCBIT2T-CHM13v2.0
Otoa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397120,682,647 - 120,762,316 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7120,680,873 - 120,762,320 (+)EnsemblGRCm39 Ensembl
GRCm387121,083,424 - 121,163,093 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7121,081,650 - 121,163,097 (+)EnsemblGRCm38mm10GRCm38
MGSCv377128,226,952 - 128,306,603 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367120,874,587 - 120,954,237 (+)NCBIMGSCv36mm8
Celera7120,996,318 - 121,074,716 (+)NCBICelera
Cytogenetic Map7F2NCBI
cM Map765.07NCBI
Otoa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81185,074,271 - 185,142,149 (+)NCBIGRCr8
mRatBN7.21175,642,978 - 175,710,528 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1175,642,975 - 175,710,435 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01191,029,861 - 191,097,524 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1191,029,861 - 191,097,290 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01197,955,647 - 198,022,686 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41179,944,477 - 180,013,040 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1173,374,030 - 173,440,021 (+)NCBICelera
Cytogenetic Map1q36NCBI
Otoa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554931,154,751 - 1,224,962 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554931,154,695 - 1,228,997 (+)NCBIChiLan1.0ChiLan1.0
OTOA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21823,736,857 - 23,819,324 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11628,257,503 - 28,339,777 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01615,530,399 - 15,657,565 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11688,025,201 - 88,094,381 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1688,025,201 - 88,091,449 (+)Ensemblpanpan1.1panPan2
OTOA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1623,106,650 - 23,175,159 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl623,106,804 - 23,168,380 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha624,602,084 - 24,670,556 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0623,245,256 - 23,313,869 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1623,047,697 - 23,116,225 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0622,956,980 - 23,029,406 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0623,345,518 - 23,414,053 (-)NCBIUU_Cfam_GSD_1.0
Otoa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344119,288,939 - 119,358,610 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365017,392,616 - 7,456,677 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365017,383,963 - 7,456,470 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OTOA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl323,570,382 - 23,662,480 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1323,570,216 - 23,662,948 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2324,012,548 - 24,055,367 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Otoa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247827,854,594 - 7,915,471 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247827,843,907 - 7,916,259 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in OTOA
2237 total Variants



ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 17 33 33 60 20


RefSeq Transcripts XM_007987802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037989751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000004977   ⟹   ENSCSAP00000003217
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl520,198,412 - 20,278,433 (+)Ensembl
RefSeq Acc Id: XM_037989751   ⟹   XP_037845679
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660689,587,651 - 9,667,862 (-)NCBI
Protein RefSeqs XP_037845679 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000003217.1
Ensembl Acc Id: ENSCSAP00000003217   ⟸   ENSCSAT00000004977
RefSeq Acc Id: XP_037845679   ⟸   XM_037989751
- UniProtKB: A0A0D9R3M8 (UniProtKB/TrEMBL)



Database
Acc Id
Source(s)
Ensembl Genes ENSCSAG00000006969 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000004977.1 UniProtKB/TrEMBL
InterPro Stereocilin-rel UniProtKB/TrEMBL
NCBI Gene OTOA ENTREZGENE
PANTHER PTHR23412 UniProtKB/TrEMBL
  PTHR23412:SF18 UniProtKB/TrEMBL
UniProt A0A0D9R3M8 ENTREZGENE, UniProtKB/TrEMBL