SEC11C (SEC11 homolog C, signal peptidase complex subunit) - Rat Genome Database

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Gene: SEC11C (SEC11 homolog C, signal peptidase complex subunit) Chlorocebus sabaeus
Analyze
Symbol: SEC11C
Name: SEC11 homolog C, signal peptidase complex subunit
RGD ID: 18650275
Description: ENCODES a protein that exhibits peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN proteolysis (inferred); signal peptide processing (inferred); ASSOCIATED WITH immunodeficiency 12 (ortholog); isolated microphthalmia 3 (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: signal peptidase complex catalytic subunit SEC11C
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11820,569,200 - 20,588,144 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1820,569,115 - 20,588,093 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660604,986,362 - 5,005,928 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SEC11C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11820,569,200 - 20,588,144 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1820,569,115 - 20,588,093 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660604,986,362 - 5,005,928 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SEC11C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381859,139,884 - 59,158,832 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1859,139,475 - 59,158,832 (+)EnsemblGRCh38hg38GRCh38
GRCh371856,807,116 - 56,826,064 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361854,958,105 - 54,977,044 (+)NCBINCBI36Build 36hg18NCBI36
Build 341854,958,104 - 54,977,041NCBI
Celera1853,525,021 - 53,543,961 (+)NCBICelera
Cytogenetic Map18q21.32NCBI
HuRef1853,515,271 - 53,534,034 (+)NCBIHuRef
CHM1_11856,802,350 - 56,821,289 (+)NCBICHM1_1
T2T-CHM13v2.01859,341,164 - 59,360,112 (+)NCBIT2T-CHM13v2.0
Sec11c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391865,933,649 - 65,950,731 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1865,933,586 - 65,950,755 (+)EnsemblGRCm39 Ensembl
GRCm381865,800,578 - 65,817,660 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1865,800,515 - 65,817,684 (+)EnsemblGRCm38mm10GRCm38
MGSCv371865,960,232 - 65,977,311 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361865,925,947 - 65,943,026 (+)NCBIMGSCv36mm8
Celera1867,074,469 - 67,091,603 (+)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1838.98NCBI
Sec11c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81861,590,905 - 61,607,247 (+)NCBIGRCr8
mRatBN7.21859,320,932 - 59,337,272 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1859,320,884 - 59,337,364 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1861,413,692 - 61,430,004 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01862,112,378 - 62,128,690 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01859,933,824 - 59,950,151 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01861,490,051 - 61,506,393 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1861,490,031 - 61,506,508 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01860,686,314 - 60,702,656 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41862,096,585 - 62,112,929 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11862,169,785 - 62,186,130 (+)NCBI
Celera1857,443,710 - 57,460,052 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
Sec11c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540243,316,966 - 43,334,136 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540243,317,038 - 43,333,816 (+)NCBIChiLan1.0ChiLan1.0
SEC11C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21776,684,853 - 76,704,240 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11862,377,467 - 62,396,854 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01852,534,718 - 52,553,726 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11855,860,710 - 55,880,060 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1855,860,471 - 55,880,060 (+)Ensemblpanpan1.1panPan2
SEC11C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1117,020,606 - 17,036,149 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl117,020,493 - 17,036,187 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha117,995,499 - 18,011,199 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0116,897,384 - 16,913,091 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl116,897,390 - 16,913,091 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1116,932,726 - 16,948,425 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0116,853,564 - 16,869,262 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0117,115,073 - 17,130,777 (-)NCBIUU_Cfam_GSD_1.0
Sec11c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494430,288,478 - 30,291,001 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364975,524,763 - 5,530,009 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364975,527,479 - 5,530,051 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEC11C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1161,754,505 - 161,769,526 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11161,754,857 - 161,769,622 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21179,382,977 - 179,397,657 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sec11c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247924,567,225 - 4,586,261 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247924,567,226 - 4,584,627 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SEC11C
608 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000016262   ⟹   ENSCSAP00000014182
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1820,569,115 - 20,588,093 (-)Ensembl
RefSeq Acc Id: XM_008013927   ⟹   XP_008012118
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11820,569,200 - 20,588,144 (-)NCBI
Vero_WHO_p1.0NW_0236660604,986,362 - 5,005,928 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037987961   ⟹   XP_037843889
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660604,986,362 - 5,005,926 (+)NCBI
RefSeq Acc Id: XM_037987962   ⟹   XP_037843890
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660604,986,362 - 5,005,926 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008012118 (Get FASTA)   NCBI Sequence Viewer  
  XP_037843889 (Get FASTA)   NCBI Sequence Viewer  
  XP_037843890 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000014182
  ENSCSAP00000014182.1
RefSeq Acc Id: XP_008012118   ⟸   XM_008013927
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RZZ3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000014182   ⟸   ENSCSAT00000016262
RefSeq Acc Id: XP_037843889   ⟸   XM_037987961
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037843890   ⟸   XM_037987962
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018166 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016262.1 UniProtKB/TrEMBL
Gene3D-CATH Umud Fragment, subunit A UniProtKB/TrEMBL
InterPro LexA/Signal_pep-like_sf UniProtKB/TrEMBL
  Pept_S26A_signal_pept_1_CS UniProtKB/TrEMBL
  Pept_S26A_signal_pept_1_Ser-AS UniProtKB/TrEMBL
  Peptidase_S24_S26A/B/C UniProtKB/TrEMBL
  Peptidase_S26 UniProtKB/TrEMBL
  Peptidase_S26B UniProtKB/TrEMBL
KEGG Report csab:103244204 UniProtKB/TrEMBL
NCBI Gene SEC11C ENTREZGENE
PANTHER PTHR10806 UniProtKB/TrEMBL
  PTHR10806:SF12 UniProtKB/TrEMBL
Pfam Peptidase_S24 UniProtKB/TrEMBL
PRINTS SIGNALPTASE UniProtKB/TrEMBL
PROSITE SPASE_I_1 UniProtKB/TrEMBL
  SPASE_I_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF51306 UniProtKB/TrEMBL
UniProt A0A0D9RZZ3 ENTREZGENE, UniProtKB/TrEMBL