ZGPAT (zinc finger CCCH-type and G-patch domain containing)

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Gene: ZGPAT (zinc finger CCCH-type and G-patch domain containing) Chlorocebus sabaeus

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Symbol:

ZGPAT

Name:

zinc finger CCCH-type and G-patch domain containing

RGD ID:

18632562

Description:

ENCODES a protein that exhibits DNA-binding transcription factor activity (inferred); DNA-binding transcription repressor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN negative regulation of epidermal growth factor-activated receptor activity (ortholog); ASSOCIATED WITH autosomal dominant nocturnal frontal lobe epilepsy (ortholog); benign familial infantile seizures 6 (ortholog); developmental and epileptic encephalopathy (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred); plasma membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

zinc finger CCCH-type with G patch domain-containing protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	494,547 - 520,081 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	494,771 - 519,519 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	48,048,248 - 48,074,527 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant nocturnal frontal lobe epilepsy (ISO)

benign familial infantile seizures 6 (ISO)

developmental and epileptic encephalopathy (ISO)

developmental and epileptic encephalopathy 33 (ISO)

early infantile epileptic encephalopathy (ISO)

neuronal ceroid lipofuscinosis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of DNA-templated transcription (IEA)

negative regulation of epidermal growth factor-activated receptor activity (ISO)

negative regulation of transcription by RNA polymerase II (IEA)

Cellular Component

nucleoplasm (IEA)

nucleus (IEA)

plasma membrane (IEA)

Molecular Function

DNA-binding transcription factor activity (IEA)

DNA-binding transcription repressor activity, RNA polymerase II-specific (IEA)

metal ion binding (IEA)

nucleic acid binding (IEA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IEA)

sequence-specific DNA binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ZGPAT
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	494,547 - 520,081 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	494,771 - 519,519 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	48,048,248 - 48,074,527 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

ZGPAT
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	63,707,442 - 63,736,142 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	63,707,465 - 63,736,142 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	62,338,794 - 62,367,494 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	61,809,238 - 61,837,938 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	20	59,023,048 - 59,051,759 (+)	NCBI		Celera
Cytogenetic Map	20	q13.33	NCBI
HuRef	20	59,071,764 - 59,099,837 (+)	NCBI		HuRef
CHM1_1	20	62,240,675 - 62,269,377 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	65,527,749 - 65,556,418 (+)	NCBI		T2T-CHM13v2.0

Zgpat
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	181,006,724 - 181,022,586 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	181,006,721 - 181,025,421 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	181,364,931 - 181,380,793 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	181,364,928 - 181,383,628 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	181,099,636 - 181,115,498 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	181,294,335 - 181,310,189 (+)	NCBI		MGSCv36	mm8
Celera	2	185,447,199 - 185,463,092 (+)	NCBI		Celera
Cytogenetic Map	2	H4	NCBI
cM Map	2	103.63	NCBI

Zgpat
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	188,851,376 - 188,867,914 (+)	NCBI		GRCr8
mRatBN7.2	3	168,473,836 - 168,490,380 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	168,473,981 - 168,490,380 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	172,854,524 - 172,870,932 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	181,813,625 - 181,830,033 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	178,475,020 - 178,491,313 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	176,865,078 - 176,881,603 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	176,865,156 - 176,881,549 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	180,575,280 - 180,591,735 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	170,505,701 - 170,521,996 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	170,411,736 - 170,428,030 (+)	NCBI
Celera	3	164,096,159 - 164,112,380 (-)	NCBI		Celera
Cytogenetic Map	3	q43	NCBI

Zgpat
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955528	493,051 - 519,780 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955528	493,051 - 519,780 (-)	NCBI	ChiLan1.0	ChiLan1.0

ZGPAT
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	69,512,897 - 69,542,511 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	69,504,916 - 69,534,518 (+)	NCBI		NHGRI_mPanPan1
PanPan1.1	20	61,630,274 - 61,662,967 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	61,630,271 - 61,662,967 (+)	Ensembl	panpan1.1		panPan2

ZGPAT
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	47,257,396 - 47,269,742 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	47,175,277 - 47,272,281 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	46,400,813 - 46,403,692 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	48,396,016 - 48,408,659 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	48,396,292 - 48,408,656 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	47,240,925 - 47,253,546 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	47,365,768 - 47,378,411 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	48,103,882 - 48,116,507 (+)	NCBI		UU_Cfam_GSD_1.0

Zgpat
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	195,511,577 - 195,526,655 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936514	10,965,219 - 10,980,194 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936514	10,965,220 - 10,980,298 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZGPAT
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	62,635,018 - 62,652,483 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	62,640,988 - 62,652,478 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

Zgpat
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	29,356,260 - 29,390,300 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624741	29,355,960 - 29,390,543 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008010726	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000014708 ⟹ ENSCSAP00000012672

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	2	494,771 - 519,519 (-)	Ensembl

RefSeq Acc Id:

XM_008010726 ⟹ XP_008008917

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	2	494,547 - 520,081 (-)	NCBI
Vero_WHO_p1.0	NW_023666050	48,048,248 - 48,074,527 (-)	NCBI

Sequence:

show sequence

GCTTCCCGGCTGCCCCCGCGCGCCAGGCACTTCCGGAAGTGGCGGCGCTCGGGAGGAAGTGCTG
GTCGGCGGCGGGGACGAAAGGGGTGCGCCGGGCCACTCTAGCCGCCCTGGTCCAGCGCCTCCCT
CTCAGCATGGACGAGGAGAGCCTGGAGTCGGCTTTGCAGACCTACCGTGCGCAGCTGCAGCAGG
TGGAGCTGGCCCTGGGCGCCGGCCTGGATTCGTCTGAGCAGGCGGACCTGCGCCAGCTACAGGG
GGACCTGAAGGAGCTCATCGAGCTCACCGAGGCCAGCCTGGTGTCTGTCAGGAAGAGCAAGTTG
CTGGCCGCGCTGGACGAAGAGCGCGCGGGCCGGGAAGATGCTGAGTACCAGGCTTTCCGGGAGG
CCATCACTGAGGCGGTGGAGGCGCCAGCAGCAGCCCCTGAGTCCGGATCAGAGACCGTTCCTAA
AGCAGAGGCGGGACCCGAATCTGCAGCAGGTGGGCAGGAGGAGGAAGAGGGAGAGGACGAGGAA
GAGCTGAGTGGGACAAAGGTGAGCGCACCCTACTACAGCTCATGGGGCACTCTGGAGTATCACA
ACGCCATGGTGGTGGGAGCGGAAGAGGCGGAGGATGGTTCGGCGGGTGTCCGTGTGCTCTACCT
GTACCCTACTCACAAATCTCTGAAGCCATGCCCGTTCTTCCTGGAGGGAAAGTGCCGCTTCAAG
GAGAACTGCAGGTTCTCCCATGGGCAGGTGGTCTCTCTGGATGAGCTGCGCCCCTTCCAGGACC
CAGACCTGAGCTCCCTGCAGGCCGGCTCTGCGTGTCTGGCCAAGCACCAGGATGGCCTCTGGCA
CGCGGCGCGCATCACCGATGTGGACAATGGCTACTACACAGTCAAGTTTGACTCGCTGCTGCTG
AGGGAGGCCGTGGTGGAGGGGGACGGCATCCTGCCCCCACTGCGCACAGAGGCCACAGAGTCTG
ACTCAGACAGCGATGGCACAGGTGACTCCAGCTATGCCAGAGTGGTGGGGTCGGACACTGTGGA
CTCCGGGACCTGCAGCTCTGCCTTTGCCGGCTGGGAGGTGCACACGCGAGGCATAGGCTCCAGA
CTTCTCACCAAGATGGGCTACGAGTTTGGCAAGGGTTTGGGCCGACATGCAGATGGCCGGGTGG
AGCCCATCCATGCTGTAGTGTTGCCACGAGGGAAGTCGCTGGACCAGTGTGTGGAGACACTGCA
GAAGCGGACCAGGGTTGGCAAGGCTGGCACCAACAAGCCCCCCAGGTGCCGGGGAAGAGGGGCC
CGGCCTGGGGGCCGCCCACCCCCTCGGAATGTGTTTGACTTCCTCAATGAAAAGCTGCAAGGCC
AGGCTCCTGGGGCCCTAGAGGCCGGGGCAGCCCCGGCGGGGAGGAGGAGCAAGGACATGTACCA
TGCCAGCAAGAGCGCCAAGCGGGCGCTGAGCCTGCGGCTCTTCCAGACCGAGGAGAAGATCGAG
CGAACCCAGCGGGACATCAGGAGCATCCAGGAGGCTCTCACCCGCAATGCTGGCCGGCATAGCG
TGGCGTCAGCCCAGCTGCAGGAGAAGCTGGCAGGAGCCCAGCGCCAGCTGGGGCAGCTCCGGGC
TCAGGAAGCAGGCCTGCAGCAGGAGCAGAGGAAGGCAGACACCCACAAGAAGATGACTGAGTTC
TAGAGAACCCTGCAAGCACTATGGATGAAGTGTGGGACCCCAGCACAGGCTGCCCTCAGAAAGA
CCAGTGTTGCCCAAGGAGGGGCCGGCCTGCTGGCCTGGGGCGTGCGGACCCTGCTGAGTGGAGA
CGGGGCTGCAGGGTCCTGTCTGGACACTTTCTTGCCCACCTGCCAGTGCCTTGGGCATTTCCTT
GGCAAGGACATTAAAGTGATTTCATCACAGTGTCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008008917	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000012672.1

RefSeq Acc Id:	XP_008008917 ⟸ XM_008010726
- UniProtKB:	A0A0D9RVN3 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000012672 ⟸ ENSCSAT00000014708

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000016628	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000014708.1	UniProtKB/TrEMBL
Gene3D-CATH	2.30.30.1190	UniProtKB/TrEMBL
	2.30.30.140	UniProtKB/TrEMBL
InterPro	G_patch_dom	UniProtKB/TrEMBL
	Znf-CCCH_4	UniProtKB/TrEMBL
	Znf_CCCH	UniProtKB/TrEMBL
	Znf_CCCH_sf	UniProtKB/TrEMBL
NCBI Gene	ZGPAT	ENTREZGENE
PANTHER	PTHR46297	UniProtKB/TrEMBL
	ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
Pfam	G-patch	UniProtKB/TrEMBL
	zf-CCCH_4	UniProtKB/TrEMBL
PROSITE	G_PATCH	UniProtKB/TrEMBL
	ZF_C3H1	UniProtKB/TrEMBL
SMART	G_patch	UniProtKB/TrEMBL
	ZnF_C3H1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF90229	UniProtKB/TrEMBL
	Tudor/PWWP/MBT	UniProtKB/TrEMBL
UniProt	A0A0D9RVN3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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