EEF1AKMT1 (EEF1A lysine methyltransferase 1) - Rat Genome Database

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Gene: EEF1AKMT1 (EEF1A lysine methyltransferase 1) Chlorocebus sabaeus
Analyze
Symbol: EEF1AKMT1
Name: EEF1A lysine methyltransferase 1
RGD ID: 18503590
Description: ENCODES a protein that exhibits histone methyltransferase activity (inferred); methyltransferase activity (inferred); nucleic acid binding (inferred); INVOLVED IN chromatin remodeling (inferred); methylation (inferred); ASSOCIATED WITH autosomal dominant nonsyndromic deafness 3B (ortholog); autosomal recessive nonsyndromic deafness 1A (ortholog); autosomal recessive nonsyndromic deafness 1B (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: eukaryotic translation elongation factor 1 alpha lysine methyltransferase 1; N(6)-adenine-specific DNA methyltransferase 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.13352,063 - 418,220 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl3352,114 - 395,586 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605744,162,212 - 44,251,990 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
EEF1AKMT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.13352,063 - 418,220 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl3352,114 - 395,586 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605744,162,212 - 44,251,990 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
EEF1AKMT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381320,728,731 - 20,773,961 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1320,728,731 - 20,773,961 (-)EnsemblGRCh38hg38GRCh38
GRCh371321,302,870 - 21,348,100 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361320,201,070 - 20,246,057 (-)NCBINCBI36Build 36hg18NCBI36
Celera132,365,009 - 2,409,998 (-)NCBICelera
Cytogenetic Map13q12.11NCBI
HuRef132,106,193 - 2,151,141 (-)NCBIHuRef
CHM1_11321,271,160 - 21,316,199 (-)NCBICHM1_1
T2T-CHM13v2.01319,921,875 - 19,967,105 (-)NCBIT2T-CHM13v2.0
Eef1akmt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391457,787,052 - 57,809,039 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1457,787,054 - 57,809,069 (-)EnsemblGRCm39 Ensembl
GRCm381457,549,595 - 57,571,582 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1457,549,597 - 57,571,612 (-)EnsemblGRCm38mm10GRCm38
MGSCv371458,168,435 - 58,190,406 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361456,503,708 - 56,525,679 (-)NCBIMGSCv36mm8
Celera1455,347,598 - 55,372,810 (-)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1430.1NCBI
Eef1akmt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81535,809,842 - 35,826,921 (-)NCBIGRCr8
mRatBN7.21531,694,284 - 31,711,367 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1531,694,292 - 31,711,336 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1533,685,599 - 33,702,678 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01534,836,283 - 34,853,362 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01533,094,363 - 33,111,443 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01537,813,115 - 37,830,932 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1537,813,115 - 37,831,031 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01541,658,536 - 41,680,058 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41536,589,142 - 36,602,237 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11536,604,841 - 36,616,940 (-)NCBI
Celera1531,405,022 - 31,418,117 (-)NCBICelera
Cytogenetic Map15p12NCBI
Eef1akmt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554971,506,742 - 1,521,850 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554971,509,855 - 1,540,786 (-)NCBIChiLan1.0ChiLan1.0
EEF1AKMT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21420,358,932 - 20,406,363 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11311,472,101 - 11,521,986 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0132,049,642 - 2,100,864 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11320,368,837 - 20,413,832 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1320,367,809 - 20,413,836 (-)Ensemblpanpan1.1panPan2
EEF1AKMT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12517,357,251 - 17,382,098 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2517,357,328 - 17,381,821 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2517,388,433 - 17,413,630 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02517,495,456 - 17,520,656 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2517,496,208 - 17,522,168 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12517,366,723 - 17,391,679 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02517,378,122 - 17,403,284 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02517,434,884 - 17,460,096 (+)NCBIUU_Cfam_GSD_1.0
Eef1akmt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945119,406,978 - 119,450,928 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936720954,556 - 998,487 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936720954,450 - 998,483 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
XPO4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl111,067,061 - 1,082,591 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1111,054,816 - 1,095,118 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.211192,862 - 220,306 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Eef1akmt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477616,903,531 - 16,921,896 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477616,875,625 - 16,918,153 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 2 60
Low 18
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000016219   ⟹   ENSCSAP00000014140
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl3352,114 - 395,586 (+)Ensembl
RefSeq Acc Id: XM_008021646   ⟹   XP_008019837
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.13352,063 - 401,842 (+)NCBI
Vero_WHO_p1.0NW_02366605744,206,697 - 44,251,990 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008021647   ⟹   XP_008019838
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.13352,157 - 418,220 (+)NCBI
Vero_WHO_p1.0NW_02366605744,183,058 - 44,251,946 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008021648   ⟹   XP_008019839
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.13352,157 - 402,251 (+)NCBI
Vero_WHO_p1.0NW_02366605744,200,178 - 44,251,943 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037986934   ⟹   XP_037842862
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605744,206,697 - 44,251,940 (-)NCBI
RefSeq Acc Id: XR_005236574
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605744,162,309 - 44,251,943 (-)NCBI
RefSeq Acc Id: XR_005236575
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605744,162,212 - 44,251,943 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008019837 (Get FASTA)   NCBI Sequence Viewer  
  XP_008019838 (Get FASTA)   NCBI Sequence Viewer  
  XP_008019839 (Get FASTA)   NCBI Sequence Viewer  
  XP_037842862 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000014140.1
Reference Protein Sequences
RefSeq Acc Id: XP_008019837   ⟸   XM_008021646
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RZV1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008019838   ⟸   XM_008021647
- Peptide Label: isoform X2
RefSeq Acc Id: XP_008019839   ⟸   XM_008021648
- Peptide Label: isoform X3
RefSeq Acc Id: ENSCSAP00000014140   ⟸   ENSCSAT00000016219
RefSeq Acc Id: XP_037842862   ⟸   XM_037986934
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RZV1 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018122 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016219.1 UniProtKB/TrEMBL
InterPro DNA_methylase_N6_adenine_CS UniProtKB/TrEMBL
  Efm5/EEF1AKMT1 UniProtKB/TrEMBL
  Mlase_EEF1AKMT1/ZCCHC4 UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
KEGG Report csab:103248960 UniProtKB/TrEMBL
NCBI Gene EEF1AKMT1 ENTREZGENE
PANTHER EEF1A LYSINE METHYLTRANSFERASE 1 UniProtKB/TrEMBL
  PTHR13200 UniProtKB/TrEMBL
Pfam N6-adenineMlase UniProtKB/TrEMBL
PROSITE N6_MTASE UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A0D9RZV1 ENTREZGENE, UniProtKB/TrEMBL