MSL1 (MSL complex subunit 1) - Rat Genome Database

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Gene: MSL1 (MSL complex subunit 1) Chlorocebus sabaeus
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Symbol: MSL1
Name: MSL complex subunit 1
RGD ID: 18492751
Description: ENCODES a protein that exhibits chromatin binding (inferred); protein-macromolecule adaptor activity (inferred); INVOLVED IN chromatin remodeling (inferred); positive regulation of DNA-templated transcription (inferred); ASSOCIATED WITH hypertrophic cardiomyopathy 25 (ortholog); FOUND IN H4 histone acetyltransferase complex (inferred); intracellular membrane-bounded organelle (inferred); MSL complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103243519; male specific lethal 1 homolog; male-specific lethal 1 homolog; uncharacterized LOC103243519
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11666,040,879 - 66,055,975 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1666,040,661 - 66,055,942 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607736,944,141 - 36,960,612 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MSL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11666,040,879 - 66,055,975 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1666,040,661 - 66,055,942 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607736,944,141 - 36,960,612 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
MSL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381740,121,971 - 40,136,917 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1740,121,971 - 40,136,917 (+)EnsemblGRCh38hg38GRCh38
GRCh371738,278,224 - 38,293,170 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361735,532,316 - 35,546,568 (+)NCBINCBI36Build 36hg18NCBI36
Celera1734,939,245 - 34,953,515 (+)NCBICelera
Cytogenetic Map17q21.1NCBI
HuRef1734,072,418 - 34,086,448 (+)NCBIHuRef
CHM1_11738,514,496 - 38,528,748 (+)NCBICHM1_1
T2T-CHM13v2.01740,985,855 - 41,000,801 (+)NCBIT2T-CHM13v2.0
Msl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391198,684,214 - 98,698,685 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1198,686,342 - 98,698,685 (+)EnsemblGRCm39 Ensembl
GRCm381198,793,508 - 98,807,862 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1198,795,516 - 98,807,859 (+)EnsemblGRCm38mm10GRCm38
MGSCv371198,657,083 - 98,669,173 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361198,611,606 - 98,622,517 (+)NCBIMGSCv36mm8
Celera11108,450,534 - 108,462,629 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1162.67NCBI
Msl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81084,251,362 - 84,263,384 (+)NCBIGRCr8
mRatBN7.21083,755,380 - 83,767,147 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1083,755,720 - 83,765,726 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1088,699,593 - 88,709,611 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01088,197,668 - 88,207,686 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01083,590,370 - 83,600,388 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01086,710,925 - 86,722,659 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1086,711,240 - 86,721,246 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01086,507,409 - 86,518,912 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41087,568,556 - 87,578,572 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1082,503,569 - 82,513,585 (+)NCBICelera
Cytogenetic Map10q31NCBI
Msl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545114,772,224 - 14,780,839 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545114,769,893 - 14,783,213 (+)NCBIChiLan1.0ChiLan1.0
MSL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21924,818,118 - 24,833,517 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11726,712,913 - 26,727,748 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01717,152,296 - 17,167,127 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11717,373,780 - 17,387,329 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1717,373,780 - 17,387,351 (-)Ensemblpanpan1.1panPan2
MSL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1922,429,371 - 22,441,686 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl922,429,522 - 22,441,767 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha921,901,643 - 21,913,922 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0923,222,191 - 23,234,472 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl923,222,204 - 23,234,365 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1921,995,939 - 22,008,217 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0922,254,672 - 22,266,943 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0922,379,645 - 22,391,924 (-)NCBIUU_Cfam_GSD_1.0
Msl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560221,825,478 - 21,839,052 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649015,236,081 - 15,249,926 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649015,236,087 - 15,249,661 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MSL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1222,224,615 - 22,237,587 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11222,224,611 - 22,237,557 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21222,502,558 - 22,515,232 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Msl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247953,068,887 - 3,083,751 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247953,070,233 - 3,083,746 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MSL1
157 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000000791   ⟹   ENSCSAP00000015274
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1666,040,661 - 66,055,942 (-)Ensembl
RefSeq Acc Id: XM_008012803   ⟹   XP_008010994
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11666,040,879 - 66,055,975 (-)NCBI
Vero_WHO_p1.0NW_02366607736,944,141 - 36,960,612 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008012804   ⟹   XP_008010995
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11666,040,899 - 66,055,975 (-)NCBI
Vero_WHO_p1.0NW_02366607736,944,141 - 36,960,612 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008010994 (Get FASTA)   NCBI Sequence Viewer  
  XP_008010995 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015274
  ENSCSAP00000015274.1
RefSeq Acc Id: XP_008010994   ⟸   XM_008012803
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S335 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008010995   ⟸   XM_008012804
- Peptide Label: isoform X2
Ensembl Acc Id: ENSCSAP00000015274   ⟸   ENSCSAT00000000791


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002774 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000791.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  6.10.250.2000 UniProtKB/TrEMBL
InterPro Msl-1 UniProtKB/TrEMBL
  MSL1_dimer UniProtKB/TrEMBL
  PEHE_dom UniProtKB/TrEMBL
KEGG Report csab:103243520 UniProtKB/TrEMBL
NCBI Gene MSL1 ENTREZGENE
PANTHER MALE-SPECIFIC LETHAL 1 HOMOLOG UniProtKB/TrEMBL
  PTHR21656 UniProtKB/TrEMBL
Pfam MSL1_dimer UniProtKB/TrEMBL
  PEHE UniProtKB/TrEMBL
SMART PEHE UniProtKB/TrEMBL
UniProt A0A0D9S335 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-03 MSL1  MSL complex subunit 1  LOC103243519  uncharacterized LOC103243519  Data merged from RGD:18652476 737654 PROVISIONAL