SERINC4 (serine incorporator 4) - Rat Genome Database

Name: SERINC4
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: SERINC4 (serine incorporator 4) Chlorocebus sabaeus

Analyze

Symbol:

SERINC4

Name:

serine incorporator 4

RGD ID:

18490456

Description:

ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); FOUND IN membrane (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SERINC4 (serine incorporator 4)	NCBI	Ortholog
Mus musculus (house mouse):	Serinc4 (serine incorporator 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Serinc4 (serine incorporator 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Serinc4 (serine incorporator 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SERINC4 (serine incorporator 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SERINC4 (serine incorporator 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Serinc4 (serine incorporator 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SERINC4 (serine incorporator 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Serinc4 (serine incorporator 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	39,244,701 - 39,249,986 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	39,244,783 - 39,249,776 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	101,741,771 - 101,747,633 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bloom syndrome (ISO)

colorectal cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

membrane (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

SERINC4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	39,244,701 - 39,249,986 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	39,244,783 - 39,249,776 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	101,741,771 - 101,747,633 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

SERINC4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	43,794,162 - 43,800,220 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	43,794,162 - 43,800,220 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	44,086,360 - 44,092,418 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	41,874,457 - 41,879,547 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	15	20,976,627 - 20,981,717 (-)	NCBI		Celera
Cytogenetic Map	15	q15.3	NCBI
HuRef	15	20,909,234 - 20,915,157 (-)	NCBI		HuRef
CHM1_1	15	44,204,625 - 44,210,548 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	15	41,601,525 - 41,607,583 (-)	NCBI		T2T-CHM13v2.0

Serinc4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	121,281,658 - 121,287,245 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	121,269,540 - 121,287,262 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	121,451,177 - 121,456,764 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	121,439,059 - 121,456,781 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	121,276,913 - 121,282,500 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	121,142,618 - 121,148,205 (-)	NCBI		MGSCv36	mm8
Celera	2	122,601,934 - 122,607,554 (-)	NCBI		Celera
Cytogenetic Map	2	E5	NCBI
cM Map	2	60.39	NCBI

Serinc4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	128,882,617 - 128,888,376 (-)	NCBI		GRCr8
mRatBN7.2	3	108,428,896 - 108,434,778 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	108,428,897 - 108,434,778 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	112,103,330 - 112,109,211 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	120,698,851 - 120,704,732 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	118,359,256 - 118,365,138 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	113,417,592 - 113,423,473 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	113,417,593 - 113,423,473 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	119,957,470 - 119,963,698 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	108,257,024 - 108,262,904 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	107,330,102 - 107,335,982 (-)	NCBI		Celera
Cytogenetic Map	3	q35	NCBI

Serinc4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955416	10,255,269 - 10,257,996 (-)	NCBI	ChiLan1.0	ChiLan1.0

SERINC4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	33,046,824 - 33,051,823 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	37,208,420 - 37,214,122 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	22,755,169 - 22,760,184 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	40,845,167 - 40,850,960 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	40,845,167 - 40,850,960 (-)	Ensembl	panpan1.1		panPan2

SERINC4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	10,537,370 - 10,541,725 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	10,538,211 - 10,542,740 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	10,595,741 - 10,601,874 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	10,673,893 - 10,680,025 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	10,674,757 - 10,679,286 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	10,583,015 - 10,589,147 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	10,704,943 - 10,711,076 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	10,824,678 - 10,830,810 (-)	NCBI		UU_Cfam_GSD_1.0

Serinc4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	89,006,030 - 89,012,033 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	6,853,921 - 6,860,164 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	6,854,102 - 6,860,106 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SERINC4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	127,760,175 - 127,765,798 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	127,760,374 - 127,764,787 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	142,591,569 - 142,594,297 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Serinc4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624804	10,819,222 - 10,823,107 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	36	1	35
Low		19	25
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008016806	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000007564 ⟹ ENSCSAP00000005738

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	26	39,245,631 - 39,247,906 (+)	Ensembl

RefSeq Acc Id:

ENSCSAT00000007566 ⟹ ENSCSAP00000005740

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	26	39,244,783 - 39,249,776 (+)	Ensembl

RefSeq Acc Id:

XM_008016806 ⟹ XP_008014997

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	26	39,244,701 - 39,249,986 (+)	NCBI
Vero_WHO_p1.0	NW_023666048	101,741,771 - 101,747,633 (-)	NCBI

Sequence:

show sequence

TCCAATGGGCTGAGGACAGAAGCAGCTGCTACTCTCATCTGCCTTCCATCTGGTGGACCTAAGC
CTAATCCCTGGGACAAGGATGGTGGGTGCCAAGGCCGGCCCCAGCCCCAGCACCTCCCTGGGCC
TGGCACAGCAGCGCAGCGGAGGCAGCAGTGTCCTAGTGAAAAGCCCCTTCTGTCAGGTGTGCTG
CTGTGGGCCTGCTCCTTGTGCCAGCTGCTGCCACTCTAGGTGGCCCTCTCTCACCGCATCCACT
TGCAGCCGCCTGTTCTACATCCTCCTCCATGTGGGGGCCTCAGCAATCTGCTGCCTCCTGCTGT
CAAGGACAGTAGTGGAAAGGGTGTGGGGCAAGACACACAGGATCCAGATGCCCTCGGGGTTGTG
TGCCCACCTGTTTGGCCTCTCTGACTGTCCAGTGCTCAGTGGCTCTGGGGCTGTGTACCGAGTA
TGTGCAGGAACCGCCACCTTCCACCTGCTGCAGGCTGTGTTGCTGGTCCACCTCCACTCCCCCA
CCAGCCCGCGGGCACAGCTGCATAATAGCTTCTGGCTCCTCAAGCTGCTGTTCCTGTTAGGTCT
CTGTGCTCTTGCCTTCTGCATTCCTGATGAGCATCTCTTCCCAGCGTGGCATTACATTGGCATC
TGTGGAGGCTTTGCATTCATCCTACTGCAGTTGGTGCTTATTACAGCTTTTGCCCATTCCTGGA
ACAAGAACTGGCAGACAGGTGCAGCTCAAGACTGCAGCTGGTTCCTGGCTGTCCTGCTGGCCAC
CCTAGGATTCTACAGCATGGCAGGTGTGGGAGCTGTGCTCCTCTTCCGCTACTATACACACCCA
GCTGGCTGCCTGCTCAACAAGATGCTCCTCAGTCTGCACCTTTGCTTCTGTGGCCTCATCTCCT
TCTTCTCCATCGCTCCTTGCATCCGCCTCAAGCAACCCCGCTCTGGCCTTCTACAAGCTTCTGT
CATCAGCTGCTACATCATGTATCTGACTTTCTCTGCGCTGTCCAGCCGTCCTCCAGAGAGAGTA
ATCCTTCAAGGACAGAATCACACCCTGTGCCTCCCTGGCCTGAGTAAAACGGAACCCCAAACAC
CAGATACCTCTCTAGCAGTGCTGAGTGCTGGCATCATGTATGCTTGTGTGCTTTTTGCTTGCAA
TGAGGCCTCCTACCTGGCTGAGGTATTTGGACCCTTGTGGATTGTCAAGGTTTACCGCTATGAG
TTTCAGAAGCCCTCACTGTGTTTCTGCTGCCCTGAAATAGTGGAGGCAGACGAAGGGCAAAGGG
GTGGTGCTGCTAGGCCAGCTGACCAAGAGACCCCTCCAGCTCCTCCAGTCCAAGTCCAGCATCT
TTCCTACAACTATTCTGCCTTCCATTTCGTCTTCTTCCTTGCCTCACTCTATGTCATGGTTACC
CTTACCAACTGGTTCAGCTATGAGGGAGCAGAACTGGAAAAGACCTTCATCAAGGGTAGCTGGG
CCACCTTCTGGGTCAAAGTTGCCTCATGCTGGGCCTGCGTACTCCTCTATCTGGGGCTGTTACT
GGCACCACTCTGTTGGTCCCCCACCCAGAAACCCCAGCCCCTTCTCTTGAGGCGCCGCCGCCAC
CACCGCATCATATCCCCAGATAACAAATATCCTCCAGTCTAAGTCCTTTTCACAAACTGGGGTT
CCCCTGACATTGTACTCCTAGAGTTGGCTCAAGGGGAACTGTCTAGCCCAGCTCAATACCTCAA
AGGACACATGGGGAGTTCTCTCTCTTTGGGCTGAAGTCAATACTATGAACTCCAAGAAGTGGTC
AAATACAGTCTAATGTGCTGGGCAGTGTCTGACTCACTGGACCTACTGTTTCTGCAT

hide sequence

Protein Sequences


Protein RefSeqs	XP_008014997	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000005738.1
	ENSCSAP00000005740
	ENSCSAP00000005740.1

RefSeq Acc Id:	XP_008014997 ⟸ XM_008016806
- UniProtKB:	A0A0D9RAV1 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000005740 ⟸ ENSCSAT00000007566

RefSeq Acc Id:

ENSCSAP00000005738 ⟸ ENSCSAT00000007564

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000009484	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000007564.1	UniProtKB/TrEMBL
	ENSCSAT00000007566.1	UniProtKB/TrEMBL
InterPro	TDE1/TMS	UniProtKB/TrEMBL
KEGG Report	csab:103245728	UniProtKB/TrEMBL
NCBI Gene	SERINC4	ENTREZGENE
PANTHER	PTHR10383	UniProtKB/TrEMBL
	PTHR10383:SF5	UniProtKB/TrEMBL
Pfam	Serinc	UniProtKB/TrEMBL
UniProt	A0A0D9RAU9_CHLSB	UniProtKB/TrEMBL
	A0A0D9RAV1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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