KIRREL1 (kirre like nephrin family adhesion molecule 1) - Rat Genome Database

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Gene: KIRREL1 (kirre like nephrin family adhesion molecule 1) Chlorocebus sabaeus
Analyze
Symbol: KIRREL1
Name: kirre like nephrin family adhesion molecule 1
RGD ID: 18480990
Description: ENCODES a protein that exhibits cell adhesion molecule binding (inferred); myosin binding (inferred); INVOLVED IN cell-cell adhesion (ortholog); negative regulation of protein phosphorylation (ortholog); positive regulation of actin filament polymerization (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); nephrotic syndrome type 23 (ortholog); FOUND IN cell projection membrane (ortholog); cell-cell junction (ortholog); dendritic shaft (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kin of IRRE like; kin of IRRE-like protein 1; KIRREL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1205,811,111 - 5,918,064 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl205,816,187 - 5,917,968 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660385,003,417 - 5,112,184 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
KIRREL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1205,811,111 - 5,918,064 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl205,816,187 - 5,917,968 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660385,003,417 - 5,112,184 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
KIRREL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381157,993,645 - 158,100,262 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1157,993,273 - 158,100,262 (+)EnsemblGRCh38hg38GRCh38
GRCh371157,963,435 - 158,070,052 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361156,229,687 - 156,332,465 (+)NCBINCBI36Build 36hg18NCBI36
Build 341154,776,135 - 154,878,919NCBI
Celera1131,034,468 - 131,136,921 (+)NCBICelera
Cytogenetic Map1q23.1NCBI
HuRef1129,321,031 - 129,423,944 (+)NCBIHuRef
CHM1_11159,359,575 - 159,462,305 (+)NCBICHM1_1
T2T-CHM13v2.01157,130,739 - 157,237,353 (+)NCBIT2T-CHM13v2.0
Kirrel1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39386,985,900 - 87,082,084 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl386,985,900 - 87,082,054 (-)EnsemblGRCm39 Ensembl
GRCm38387,078,593 - 87,174,777 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl387,078,593 - 87,174,747 (-)EnsemblGRCm38mm10GRCm38
MGSCv37386,882,514 - 86,978,669 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36387,168,739 - 87,227,036 (-)NCBIMGSCv36mm8
Celera387,105,684 - 87,203,142 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map338.18NCBI
Kirrel1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82174,819,564 - 174,912,998 (-)NCBIGRCr8
mRatBN7.22172,521,644 - 172,615,057 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2172,525,245 - 172,615,299 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2179,676,244 - 179,730,913 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02177,698,563 - 177,753,230 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02172,286,976 - 172,341,500 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02186,420,743 - 186,515,209 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2186,420,795 - 186,515,135 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02205,825,636 - 205,919,683 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42179,114,757 - 179,169,185 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12179,064,862 - 179,119,291 (-)NCBI
Celera2166,483,236 - 166,536,703 (-)NCBICelera
Cytogenetic Map2q34NCBI
Kirrel1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554689,821,303 - 9,916,667 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554689,820,649 - 9,919,958 (+)NCBIChiLan1.0ChiLan1.0
KIRREL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2191,736,817 - 91,842,857 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1191,480,731 - 91,586,707 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01133,363,880 - 133,465,717 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11137,237,218 - 137,261,101 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1137,233,701 - 137,255,927 (+)Ensemblpanpan1.1panPan2
KIRREL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13823,530,930 - 23,593,957 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3823,530,885 - 23,594,236 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3823,556,953 - 23,620,213 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03823,696,328 - 23,762,792 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3823,699,336 - 23,763,035 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13823,440,193 - 23,506,559 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03823,993,900 - 24,059,856 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03824,394,780 - 24,461,104 (-)NCBIUU_Cfam_GSD_1.0
Kirrel1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050583,719,999 - 3,761,108 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936847821,479 - 841,988 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936847820,538 - 844,829 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KIRREL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl492,176,746 - 92,290,610 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1492,173,897 - 92,290,887 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24100,513,435 - 100,628,217 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Kirrel1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247942,829,496 - 2,922,352 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247942,824,716 - 2,922,300 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 4 3
Low 32 18 57
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000000391   ⟹   ENSCSAP00000015666
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl205,816,187 - 5,917,968 (-)Ensembl
RefSeq Acc Id: XM_007976634   ⟹   XP_007974825
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1205,811,111 - 5,917,916 (-)NCBI
Vero_WHO_p1.0NW_0236660385,003,417 - 5,112,184 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007976635   ⟹   XP_007974826
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1205,811,111 - 5,917,916 (-)NCBI
Vero_WHO_p1.0NW_0236660385,003,417 - 5,112,184 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007976636   ⟹   XP_007974827
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1205,811,111 - 5,917,916 (-)NCBI
Vero_WHO_p1.0NW_0236660385,003,417 - 5,112,184 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007976637   ⟹   XP_007974828
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1205,811,111 - 5,917,916 (-)NCBI
Vero_WHO_p1.0NW_0236660385,003,417 - 5,111,970 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007976638   ⟹   XP_007974829
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1205,811,111 - 5,918,064 (-)NCBI
Vero_WHO_p1.0NW_0236660385,003,417 - 5,111,970 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_007974829   ⟸   XM_007976638
- Peptide Label: isoform X5
- UniProtKB: A0A0D9S477 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007974828   ⟸   XM_007976637
- Peptide Label: isoform X4
RefSeq Acc Id: XP_007974826   ⟸   XM_007976635
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007974827   ⟸   XM_007976636
- Peptide Label: isoform X3
RefSeq Acc Id: XP_007974825   ⟸   XM_007976634
- Peptide Label: isoform X1
RefSeq Acc Id: ENSCSAP00000015666   ⟸   ENSCSAT00000000391


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002376 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000391.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
NCBI Gene KIRREL1 ENTREZGENE
PANTHER KIN OF IRRE-LIKE PROTEIN 1 UniProtKB/TrEMBL
  NEPHRIN UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A0D9S477 ENTREZGENE, UniProtKB/TrEMBL