LDLRAD4 (low density lipoprotein receptor class A domain containing 4) - Rat Genome Database

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Gene: LDLRAD4 (low density lipoprotein receptor class A domain containing 4) Chlorocebus sabaeus
Analyze
Symbol: LDLRAD4
Name: low density lipoprotein receptor class A domain containing 4
RGD ID: 18465840
Description: ENCODES a protein that exhibits R-SMAD binding (inferred); INVOLVED IN negative regulation of cell migration (inferred); negative regulation of epithelial to mesenchymal transition (inferred); negative regulation of signal transduction (inferred); ASSOCIATED WITH chromosome 18p deletion syndrome (ortholog); intellectual disability (ortholog); FOUND IN early endosome membrane (inferred); endosome (inferred); Golgi membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: low-density lipoprotein receptor class A domain-containing protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11871,705,206 - 72,132,544 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1872,094,321 - 72,125,592 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605046,759,534 - 47,199,124 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LDLRAD4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11871,705,206 - 72,132,544 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1872,094,321 - 72,125,592 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605046,759,534 - 47,199,124 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LDLRAD4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381813,217,682 - 13,652,754 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1813,217,498 - 13,652,755 (+)EnsemblGRCh38hg38GRCh38
GRCh371813,217,681 - 13,652,753 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361813,208,795 - 13,642,753 (+)NCBINCBI36Build 36hg18NCBI36
Build 341813,610,866 - 13,642,753NCBI
Celera1813,101,030 - 13,535,088 (+)NCBICelera
Cytogenetic Map18p11.21NCBI
HuRef1813,172,315 - 13,607,009 (+)NCBIHuRef
CHM1_11813,218,367 - 13,652,114 (+)NCBICHM1_1
T2T-CHM13v2.01813,380,438 - 13,815,606 (+)NCBIT2T-CHM13v2.0
Ldlrad4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391868,065,345 - 68,393,621 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1868,066,328 - 68,401,701 (+)EnsemblGRCm39 Ensembl
GRCm381867,932,274 - 68,260,550 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1867,933,257 - 68,268,630 (+)EnsemblGRCm38mm10GRCm38
MGSCv371868,092,911 - 68,415,203 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361868,058,626 - 68,380,918 (+)NCBIMGSCv36mm8
Celera1869,232,373 - 69,563,908 (+)NCBICelera
Cytogenetic Map18E2NCBI
cM Map1840.14NCBI
Ldlrad4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81863,789,089 - 64,118,166 (+)NCBIGRCr8
mRatBN7.21861,519,253 - 61,848,403 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1861,521,428 - 61,843,238 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1863,722,243 - 63,918,315 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01864,427,017 - 64,623,184 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01862,272,000 - 62,467,935 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01863,717,423 - 64,045,224 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1863,882,610 - 64,044,023 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01863,020,278 - 63,219,634 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41864,755,404 - 64,788,816 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1859,750,235 - 59,946,262 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
Ldlrad4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955402384,177 - 508,876 (-)NCBIChiLan1.0ChiLan1.0
LDLRAD4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21724,390,591 - 24,829,455 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11810,083,187 - 10,522,217 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v018669,862 - 1,110,558 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1182,838,111 - 2,879,363 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl182,845,198 - 2,879,363 (-)Ensemblpanpan1.1panPan2
LDLRAD4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1124,541,702 - 24,927,435 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl124,541,811 - 24,925,464 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha125,527,314 - 25,913,839 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0124,448,554 - 24,835,999 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl124,448,556 - 24,835,772 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1124,498,406 - 24,884,117 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0124,385,328 - 24,772,177 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0124,658,465 - 25,044,530 (-)NCBIUU_Cfam_GSD_1.0
Ldlrad4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049443,502,377 - 3,860,211 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366262,865,352 - 3,081,703 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366262,730,689 - 3,088,527 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LDLRAD4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl696,401,654 - 96,577,643 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1696,401,650 - 96,578,162 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2689,708,022 - 89,884,466 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Ldlrad4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477020,137,979 - 20,269,714 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LDLRAD4
12029 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007974745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007974746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007974747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007974748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007974749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007974750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007974751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007974752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007974754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007974755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007974756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007974757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007974758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007974759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007974760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037982532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037982533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000015584   ⟹   ENSCSAP00000013521
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1872,094,321 - 72,125,592 (+)Ensembl
RefSeq Acc Id: XM_007974745   ⟹   XP_007972936
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11871,706,034 - 72,132,544 (+)NCBI
Vero_WHO_p1.0NW_02366605046,760,260 - 47,198,878 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007974746   ⟹   XP_007972937
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11871,705,488 - 72,132,544 (+)NCBI
Vero_WHO_p1.0NW_02366605046,759,534 - 47,198,878 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007974750   ⟹   XP_007972941
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11871,764,226 - 72,132,544 (+)NCBI
Vero_WHO_p1.0NW_02366605046,817,416 - 47,199,124 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007974751   ⟹   XP_007972942
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11871,869,452 - 72,132,544 (+)NCBI
Vero_WHO_p1.0NW_02366605046,922,957 - 47,199,124 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007974756   ⟹   XP_007972947
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11872,092,155 - 72,132,544 (+)NCBI
Vero_WHO_p1.0NW_02366605047,157,734 - 47,199,124 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007974757   ⟹   XP_007972948
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11871,706,035 - 72,132,544 (+)NCBI
Vero_WHO_p1.0NW_02366605046,760,260 - 47,198,878 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007974760   ⟹   XP_007972951
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11872,122,385 - 72,132,544 (+)NCBI
Vero_WHO_p1.0NW_02366605047,188,946 - 47,199,124 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037982532   ⟹   XP_037838460
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605046,916,717 - 47,199,124 (+)NCBI
RefSeq Acc Id: XM_037982533   ⟹   XP_037838461
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605046,760,260 - 47,198,878 (+)NCBI
RefSeq Acc Id: XP_007972937   ⟸   XM_007974746
- Peptide Label: isoform X1
RefSeq Acc Id: XP_007972936   ⟸   XM_007974745
- Peptide Label: isoform X1
RefSeq Acc Id: XP_007972948   ⟸   XM_007974757
- Peptide Label: isoform X3
RefSeq Acc Id: XP_007972941   ⟸   XM_007974750
- Peptide Label: isoform X1
RefSeq Acc Id: XP_007972942   ⟸   XM_007974751
- Peptide Label: isoform X1
RefSeq Acc Id: XP_007972947   ⟸   XM_007974756
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RY32 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007972951   ⟸   XM_007974760
- Peptide Label: isoform X5
Ensembl Acc Id: ENSCSAP00000013521   ⟸   ENSCSAT00000015584
RefSeq Acc Id: XP_037838461   ⟸   XM_037982533
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037838460   ⟸   XM_037982532
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017490 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000015584.1 UniProtKB/TrEMBL
InterPro TMEPAI/LRAD4 UniProtKB/TrEMBL
NCBI Gene LDLRAD4 ENTREZGENE
PANTHER LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 4 UniProtKB/TrEMBL
  PTHR16514 UniProtKB/TrEMBL
UniProt A0A0D9RY32 ENTREZGENE, UniProtKB/TrEMBL