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Gene: DDX27 (DEAD-box helicase 27) Chlorocebus sabaeus

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Symbol:

DDX27

Name:

DEAD-box helicase 27

RGD ID:

18461546

Description:

ENCODES a protein that exhibits ATP binding (inferred); helicase activity (inferred); hydrolase activity (inferred); INVOLVED IN rRNA processing (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 26 (ortholog); FOUND IN chromosome (ortholog); nucleolus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

probable ATP-dependent RNA helicase DDX27

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DDX27 (DEAD-box helicase 27)	NCBI	Ortholog
Mus musculus (house mouse):	Ddx27 (DEAD box helicase 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Ddx27 (DEAD-box helicase 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ddx27 (DEAD-box helicase 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DDX27 (DEAD-box helicase 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DDX27 (DEAD-box helicase 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ddx27 (DEAD-box helicase 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DDX27 (DEAD-box helicase 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ddx27 (DEAD-box helicase 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	14,741,882 - 14,766,900 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	14,742,113 - 14,766,933 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	63,231,975 - 63,256,926 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

developmental and epileptic encephalopathy 26 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

rRNA processing (ISO)

Cellular Component

chromosome (ISO)

cytosol (IEA)

nucleolus (ISO)

Molecular Function

ATP binding (IEA)

helicase activity (IEA)

hydrolase activity (IEA)

nucleic acid binding (IEA)

protein binding (ISO)

RNA helicase activity (IEA)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

DDX27
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	14,741,882 - 14,766,900 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	14,742,113 - 14,766,933 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	63,231,975 - 63,256,926 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

DDX27
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	49,219,416 - 49,244,073 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	49,219,347 - 49,244,077 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	47,835,953 - 47,860,610 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	47,269,291 - 47,294,021 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	47,269,290 - 47,294,019	NCBI
Celera	20	44,540,460 - 44,565,227 (+)	NCBI		Celera
Cytogenetic Map	20	q13.13	NCBI
HuRef	20	44,584,608 - 44,609,377 (+)	NCBI		HuRef
CHM1_1	20	47,740,185 - 47,765,013 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	50,988,932 - 51,013,575 (+)	NCBI		T2T-CHM13v2.0

Ddx27
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	166,857,233 - 166,876,865 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	166,857,113 - 166,876,867 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	167,015,313 - 167,034,945 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	167,015,193 - 167,034,947 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	166,840,813 - 166,860,445 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	166,706,518 - 166,717,018 (+)	NCBI		MGSCv36	mm8
Celera	2	172,955,191 - 172,974,952 (+)	NCBI		Celera
Cytogenetic Map	2	H3	NCBI
cM Map	2	87.22	NCBI

Ddx27
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	176,163,220 - 176,182,418 (+)	NCBI		GRCr8
mRatBN7.2	3	155,744,182 - 155,763,380 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	155,744,150 - 155,763,372 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	159,545,494 - 159,564,670 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	168,044,467 - 168,063,643 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	165,786,175 - 165,805,351 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	163,767,236 - 163,786,408 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	163,767,173 - 163,786,445 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	169,927,524 - 169,946,728 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	158,165,670 - 158,185,490 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	158,071,719 - 158,091,133 (+)	NCBI
Celera	3	154,325,693 - 154,370,898 (+)	NCBI		Celera
Cytogenetic Map	3	q42	NCBI

Ddx27
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955445	8,881,062 - 8,899,905 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955445	8,881,062 - 8,899,895 (-)	NCBI	ChiLan1.0	ChiLan1.0

DDX27
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	54,960,971 - 54,986,235 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	54,954,077 - 54,979,335 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	45,557,430 - 45,582,569 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	46,626,761 - 46,647,238 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	46,621,585 - 46,647,238 (+)	Ensembl	panpan1.1		panPan2

DDX27
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	35,911,622 - 35,930,597 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	35,869,470 - 35,930,566 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	35,154,359 - 35,173,309 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	36,616,595 - 36,635,540 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	36,616,661 - 36,635,586 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	35,857,077 - 35,876,020 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	35,991,713 - 36,010,711 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	36,532,956 - 36,552,144 (+)	NCBI		UU_Cfam_GSD_1.0

Ddx27
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	189,537,864 - 189,555,889 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936514	4,990,617 - 5,009,569 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936514	4,992,028 - 5,009,516 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DDX27
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	50,903,284 - 50,924,807 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	50,903,247 - 50,923,484 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	57,224,578 - 57,234,021 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Ddx27
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624790	6,100,414 - 6,123,048 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624790	6,105,222 - 6,123,022 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in DDX27
570 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008014525	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000013090 ⟹ ENSCSAP00000011102

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	2	14,742,113 - 14,766,933 (-)	Ensembl

RefSeq Acc Id:

XM_008014525 ⟹ XP_008012716

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	2	14,741,882 - 14,766,900 (-)	NCBI
Vero_WHO_p1.0	NW_023666050	63,231,975 - 63,256,926 (-)	NCBI

Sequence:

show sequence

ATGGTACATGCGCAATGACGACGAGGAGGTTGCGAAAAGTCAATTGCTGGTCCGCACGCTGTGC
TTGCTTCCGGAAGTGGCTTCTGCGACAACATGCTTGCGGACCTTGGCTTAATCGGGACCATAGG
CGAGGATGACGAGGTGCCGGTGGAGCCCGAGTCTGACTCCGGTGACGAGGAAGAAGAGGGGCCT
ATTGTGCTGGGCAGACGACAAAAAGCCTTGGGGAAGAACCGCAGTGCTGATTTCAATCCTGACT
TTGTTTTCACTGAGAAGGAGGGGACTTATGATGGCAGCTGGGCCCTGGCTGATGTCATGAGCCA
ACTCAAGAAGAAGAGGGCAGCCACTACATTAGATGAGAAGATTGAGAAAGTTCGAAAGAAAAGG
AAAACAGAGGTTAAAGAAGCCAAGTCTGGGAATTTGGAGAAGGAGAAAGAAACAAAGGAGGGCT
CTGAACCAAAAGAGCAGGAAGACCTTCAAGGGAATGATGAGGAAGGCTCAGAAGATGAAGCCTC
AGAGACCGACTACTCATCAGCTGATGAGAACATCCTCACCAAAGCAGATACACTCAAAGTAAAG
GATCGGAAGAAGAAGAAGAAAGGACAGGAAGCAGGAGGATTTTTTGAAGATGCATCTCAGTACG
ATGAAAACCTCTCGTTCCAGGACATGAACCTTTCCCGCCCTCTTCTGAAGGCCATTACAGCCAT
GGGCTTCAAGCAGCCCACCCCGATCCAGAAGGCGTGCATACCTGTGGGTCTGTTGGGGAAGGAC
ATCTGTGCCTGTGCAGCCACTGGGACAGGTAAAACTGCTGCCTTTGCCCTGCCTGTCTTGGAGC
GTCTGATTTACAAACCCCGCCAGGCTCCAGTCACCCGCGTGCTGGTGCTGGTGCCCACCCGAGA
GCTGGGCATCCAGGTGCACTCTGTCACCAGACAGCTGGCCCAGTTCTGCAACATCACCACTTGC
CTGGCTGTGGGCGGCTTGGACGTGAAGTCTCAGGAAGCAGCTCTTCGGGCAGCACCTGACATCC
TCATCGCCACCCCAGGCCGGCTCATCGATCACCTCCACAACTGCCCTTCCTTCCACCTGAGCAG
CATCGAGGTGCTCATCCTGGACGAGGCTGACAGGATGCTGGATGAGTACTTTGAGGAGCAGATG
AAGGAGATCATCCGAATGTGTTCCCACCACCGCCAGACCATGCTCTTCTCAGCCACCATGACAG
ACGAGGTGAAAGATCTGGCTTCTGTCTCCTTGAAGAATCCTGTCCGGATATTTGTGAACAGCAA
CACGGATGTGGCTCCCTTCCTGCGGCAGGAGTTCATCCGGATCCGGCCTAATCGGGAAGGAGAC
CGGGAAGCCATCGTGGCAGCCTTGTTGACGAGGACCTTCACTGACCATGTGATGCTGTTCACGC
AGACCAAGAAGCAGGCCCACCGCATGCACATCCTCCTGGGGCTCATGGGACTGCAGGTGGGCGA
GCTCCATGGCAACTTGTCACAGACGCAGCGGCTGGAGGCCCTCCGGCGTTTTAAGGATGAACAG
ATTGACATCCTCGTGGCCACTGATGTGGCAGCCCGTGGACTTGATATTGAGGGGGTCAAAACGG
TAATCAACTTCACAATGCCTAATACTATCAAACATTATGTCCACCGGGTGGGGCGAACAGCGCG
TGCTGGCAGGGCTGGGCGCTCAGTCTCTCTGGTGGGAGAAGATGAGCGGAAGATGCTGAAGGAG
ATTGTAAAAGCTGCCAAGGCCCCTGTGAAGGCCAGGATACTTCCCCAAGATGTCATCCTCAAAT
TCCGGGACAAGATTGAGAAAATGGAGAAAGATGTGTATGCAGTTCTGCAGCTAGAGGCGGAGGA
GAAAGAGATGCAGCAGTCGGAAGCCCAGATCAATACAGCAAAGCGGCTCCTAGAGAAGGGGAAG
GAGGCAGTGGTCCAAGAGCCCGAGAGGAACTGGTTCCAGACCAAAGAAGAGAGGAAGAAGGAGA
AAATTGCCAAAGCTCTGCAGGAATTTGACTTGGCCTTAAGAGGAAAGAAGAAAAGGAAGAAGTT
TATGAAGGATGCCAAAAAAAAGGGGGAGATGACAGCAGAGGAAAGGTCCCAGTTTGAAATCCTC
AAGGCGCAGATGTTTGCTGAACGGCTAGCGAAGAGGAATCGCAGAGCCAAGCGGGCCCGAGCAA
TGCCTGAGGAGGAGCCAGTGAGAGGTCCTGCCAAGAAGCAAAAGCAGGGGAAGAAATCTGTATT
TGATGAAGAACTCACCAACACAAGCAAGAAGGCCCTGAAACAGTATCGAGCTGGCCCTTCTTTT
GAAGAAAGGAAACAGTTGGGCTTGCCCCACCAGAGACGAGGAGGAAACTTTAAATCTAAATCCA
GATACAAGAGGAGGAAGTAGCTGTTGTGGCCTGAAGAAATTCATGGGGGCAGCCCTTAAATCCC
TTCCCTGTGGGAAGTCATCCTGGCTGGTCTGTCTTTTCTCCATTTGTTCAAAAAACAAAAAAAA
AGTTTGGTGTGGTGGTATGGTATGTAGCTATTTTCCTAAGCATGTCTATCAATCTCCTTTCTTG
CTGATTAGCTTTCACATAATGACTATATTAAATGGAAGTATTTTTGGAAGAGAAACCAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008012716	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000011102.1

RefSeq Acc Id:	XP_008012716 ⟸ XM_008014525
- UniProtKB:	A0A0D9RR63 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000011102 ⟸ ENSCSAT00000013090

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000014996	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000013090.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	DEAD/DEAH_box_helicase_dom	UniProtKB/TrEMBL
	DEAD_box_RNA_helicase	UniProtKB/TrEMBL
	Helicase_ATP-bd	UniProtKB/TrEMBL
	Helicase_C	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	RNA-helicase_DEAD-box_CS	UniProtKB/TrEMBL
	RNA_helicase_DEAD_Q_motif	UniProtKB/TrEMBL
NCBI Gene	DDX27	ENTREZGENE
PANTHER	ATP-DEPENDENT RNA HELICASE RHLE-RELATED	UniProtKB/TrEMBL
	RNA HELICASE	UniProtKB/TrEMBL
Pfam	DEAD	UniProtKB/TrEMBL
	Helicase_C	UniProtKB/TrEMBL
PROSITE	DEAD_ATP_HELICASE	UniProtKB/TrEMBL
	HELICASE_ATP_BIND_1	UniProtKB/TrEMBL
	HELICASE_CTER	UniProtKB/TrEMBL
	Q_MOTIF	UniProtKB/TrEMBL
SMART	DEXDc	UniProtKB/TrEMBL
	HELICc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A0D9RR63	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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