LMO2 (LIM domain only 2) - Rat Genome Database

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Gene: LMO2 (LIM domain only 2) Chlorocebus sabaeus
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Symbol: LMO2
Name: LIM domain only 2
RGD ID: 18438401
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); identical protein binding (ortholog); INVOLVED IN embryonic hemopoiesis (ortholog); negative regulation of erythrocyte differentiation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); COVID-19 (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rhombotin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1131,382,437 - 31,416,256 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl131,404,872 - 31,416,883 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038128,481,321 - 128,514,918 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LMO2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1131,382,437 - 31,416,256 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl131,404,872 - 31,416,883 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038128,481,321 - 128,514,918 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LMO2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381133,858,576 - 33,892,076 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1133,858,576 - 33,892,076 (-)EnsemblGRCh38hg38GRCh38
GRCh371133,880,122 - 33,913,623 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361133,836,698 - 33,870,412 (-)NCBINCBI36Build 36hg18NCBI36
Build 341133,836,700 - 33,870,412NCBI
Celera1134,027,627 - 34,061,421 (-)NCBICelera
Cytogenetic Map11p13NCBI
HuRef1133,576,315 - 33,610,063 (-)NCBIHuRef
CHM1_11133,879,643 - 33,913,368 (-)NCBICHM1_1
T2T-CHM13v2.01133,995,616 - 34,029,225 (-)NCBIT2T-CHM13v2.0
Lmo2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392103,788,309 - 103,812,223 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2103,788,331 - 103,812,223 (+)EnsemblGRCm39 Ensembl
GRCm382103,957,903 - 103,981,878 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2103,957,986 - 103,981,878 (+)EnsemblGRCm38mm10GRCm38
MGSCv372103,798,152 - 103,822,035 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362103,771,062 - 103,782,713 (+)NCBIMGSCv36mm8
Celera2105,204,167 - 105,227,999 (+)NCBICelera
Cytogenetic Map2E2NCBI
cM Map254.46NCBI
Lmo2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83110,810,162 - 110,832,895 (+)NCBIGRCr8
mRatBN7.2390,355,234 - 90,377,970 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl390,365,883 - 90,377,953 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx393,848,260 - 93,870,995 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03102,447,339 - 102,470,072 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03100,277,857 - 100,300,590 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0393,909,156 - 93,931,888 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl393,909,156 - 93,931,871 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03100,549,307 - 100,572,039 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4389,356,199 - 89,367,641 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1389,252,944 - 89,263,314 (+)NCBI
Celera389,416,677 - 89,439,412 (+)NCBICelera
Cytogenetic Map3q32NCBI
Lmo2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542212,354,845 - 12,362,470 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542212,354,865 - 12,362,026 (+)NCBIChiLan1.0ChiLan1.0
LMO2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2936,077,833 - 36,110,953 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11136,082,565 - 36,115,729 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01133,830,370 - 33,863,960 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11133,712,099 - 33,720,729 (-)NCBIpanpan1.1PanPan1.1panPan2
LMO2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha1833,481,882 - 33,492,473 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01834,487,785 - 34,497,780 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1834,486,702 - 34,497,791 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11834,045,610 - 34,056,746 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01833,639,096 - 33,649,686 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01834,274,467 - 34,285,055 (+)NCBIUU_Cfam_GSD_1.0
Lmo2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494730,982,272 - 30,992,326 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365334,107,067 - 4,117,222 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365334,107,073 - 4,117,121 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LMO2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl227,044,763 - 27,055,453 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1227,033,924 - 27,055,457 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2229,401,270 - 29,422,801 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Lmo2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476713,245,984 - 13,257,440 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476713,245,783 - 13,257,322 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000003402   ⟹   ENSCSAP00000001680
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl131,404,872 - 31,416,883 (+)Ensembl
RefSeq Acc Id: XM_008002411   ⟹   XP_008000602
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1131,382,922 - 31,416,256 (+)NCBI
Vero_WHO_p1.0NW_023666038128,482,054 - 128,514,918 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008002421   ⟹   XP_008000612
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1131,382,437 - 31,416,256 (+)NCBI
Vero_WHO_p1.0NW_023666038128,481,321 - 128,514,918 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008002431   ⟹   XP_008000622
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1131,392,780 - 31,416,256 (+)NCBI
Vero_WHO_p1.0NW_023666038128,491,680 - 128,514,918 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008002434   ⟹   XP_008000625
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1131,404,175 - 31,416,256 (+)NCBI
Vero_WHO_p1.0NW_023666038128,503,028 - 128,514,918 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037999524   ⟹   XP_037855452
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038128,503,145 - 128,514,918 (+)NCBI
RefSeq Acc Id: XP_008000612   ⟸   XM_008002421
- Peptide Label: isoform X2
RefSeq Acc Id: XP_008000602   ⟸   XM_008002411
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008000622   ⟸   XM_008002431
- Peptide Label: isoform X3
RefSeq Acc Id: XP_008000625   ⟸   XM_008002434
- Peptide Label: isoform X4
- UniProtKB: A0A0D9QZ91 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000001680   ⟸   ENSCSAT00000003402
RefSeq Acc Id: XP_037855452   ⟸   XM_037999524
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000005369 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000003402.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine Rich Protein UniProtKB/TrEMBL
InterPro LMO_RBTN_TF UniProtKB/TrEMBL
  Znf_LIM UniProtKB/TrEMBL
NCBI Gene LMO2 ENTREZGENE
PANTHER LD11652P UniProtKB/TrEMBL
  RHOMBOTIN-2 UniProtKB/TrEMBL
Pfam LIM UniProtKB/TrEMBL
PROSITE LIM_DOMAIN_1 UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/TrEMBL
SMART LIM UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
UniProt A0A0D9QZ91 ENTREZGENE, UniProtKB/TrEMBL