TRABD2A (TraB domain containing 2A) - Rat Genome Database

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Pathways
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Gene: TRABD2A (TraB domain containing 2A) Chlorocebus sabaeus
Analyze
Symbol: TRABD2A
Name: TraB domain containing 2A
RGD ID: 18429915
Description: ENCODES a protein that exhibits endopeptidase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN negative regulation of Wnt signaling pathway (inferred); proteolysis (inferred); Wnt signaling pathway (inferred); FOUND IN membrane (inferred); organelle membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: metalloprotease TIKI1
RGD Orthologs
Human
Bonobo
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11422,297,687 - 22,355,100 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1422,297,888 - 22,354,844 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604590,060,199 - 90,153,693 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TRABD2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11422,297,687 - 22,355,100 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1422,297,888 - 22,354,844 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604590,060,199 - 90,153,693 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TRABD2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38284,901,643 - 84,907,021 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl284,821,650 - 84,907,008 (-)EnsemblGRCh38hg38GRCh38
GRCh37285,048,774 - 85,108,369 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36284,902,305 - 84,961,763 (-)NCBINCBI36Build 36hg18NCBI36
Celera284,877,582 - 84,937,027 (-)NCBICelera
Cytogenetic Map2p11.2NCBI
HuRef284,944,790 - 85,004,357 (-)NCBIHuRef
CHM1_1285,058,534 - 85,063,888 (-)NCBICHM1_1
T2T-CHM13v2.0284,903,468 - 84,909,118 (-)NCBIT2T-CHM13v2.0
TRABD2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21241,495,946 - 41,555,796 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A41,498,706 - 41,558,653 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A84,875,464 - 84,979,886 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A86,433,980 - 86,493,762 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A86,433,980 - 86,493,762 (-)Ensemblpanpan1.1panPan2
Trabd2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024406292448,866 - 575,961 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366503,622,680 - 3,666,408 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRABD2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1359,806,470 - 59,857,941 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2362,846,052 - 62,902,483 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Trabd2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474918,236,834 - 18,265,145 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 1 16 18
Below cutoff 35 4 42

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000014133   ⟹   ENSCSAP00000012112
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1422,297,888 - 22,354,844 (+)Ensembl
RefSeq Acc Id: XM_007970040   ⟹   XP_007968231
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11422,297,687 - 22,355,100 (+)NCBI
Vero_WHO_p1.0NW_02366604590,060,199 - 90,153,689 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038007171   ⟹   XP_037863099
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604590,112,741 - 90,153,693 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007968231 (Get FASTA)   NCBI Sequence Viewer  
  XP_037863099 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000012112.1
Reference Protein Sequences
RefSeq Acc Id: XP_007968231   ⟸   XM_007970040
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RU23 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000012112   ⟸   ENSCSAT00000014133
RefSeq Acc Id: XP_037863099   ⟸   XM_038007171
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016047 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014133.1 UniProtKB/TrEMBL
InterPro TIKI1/2-like UniProtKB/TrEMBL
  TraB_fam UniProtKB/TrEMBL
KEGG Report csab:103219962 UniProtKB/TrEMBL
NCBI Gene TRABD2A ENTREZGENE
PANTHER METALLOPROTEASE TIKI1 UniProtKB/TrEMBL
  PTHR31120 UniProtKB/TrEMBL
Pfam TraB UniProtKB/TrEMBL
UniProt A0A0D9RU23 ENTREZGENE, UniProtKB/TrEMBL