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Gene: PLAAT4 (phospholipase A and acyltransferase 4) Chlorocebus sabaeus

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Symbol:

PLAAT4

Name:

phospholipase A and acyltransferase 4

RGD ID:

18422752

Description:

ENCODES a protein that exhibits N-acyltransferase activity (inferred); phospholipase A1 activity (inferred); phospholipase A2 activity (inferred); INVOLVED IN positive regulation of protein-glutamine gamma-glutamyltransferase activity (ortholog); ASSOCIATED WITH intellectual disability (ortholog); leukocyte adhesion deficiency 3 (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

RARRES3; retinoic acid receptor responder 3; retinoic acid receptor responder protein 3

RGD Orthologs

Human

Bonobo

Dog

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	10,695,127 - 10,704,564 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	10,692,839 - 10,704,649 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	108,042,597 - 108,051,007 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

intellectual disability (ISO)

leukocyte adhesion deficiency 3 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

lipid metabolic process (IEA)

N-acylphosphatidylethanolamine metabolic process (IEA)

phospholipid metabolic process (IEA)

positive regulation of keratinocyte differentiation (IEA)

positive regulation of protein-glutamine gamma-glutamyltransferase activity (ISO)

Cellular Component

cytoplasm (IEA)

membrane (IEA)

Molecular Function

N-acyltransferase activity (IEA)

phospholipase A1 activity (IEA)

phospholipase A2 activity (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

PLAAT4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	10,695,127 - 10,704,564 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	10,692,839 - 10,704,649 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	108,042,597 - 108,051,007 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

PLAAT4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	63,536,808 - 63,546,458 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	63,536,808 - 63,548,808 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	63,304,280 - 63,313,930 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	63,060,849 - 63,070,506 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	63,060,855 - 63,070,505	NCBI
Celera	11	60,628,359 - 60,638,016 (+)	NCBI		Celera
Cytogenetic Map	11	q12.3	NCBI
HuRef	11	59,633,141 - 59,642,798 (+)	NCBI		HuRef
CHM1_1	11	63,187,279 - 63,196,936 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	63,526,070 - 63,535,720 (+)	NCBI		T2T-CHM13v2.0

PLAAT4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	64,758,650 - 64,768,719 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	65,803,855 - 65,813,923 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	58,889,014 - 58,898,757 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	62,240,322 - 62,249,990 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	62,240,321 - 62,249,990 (+)	Ensembl	panpan1.1		panPan2

PLAAT4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	53,418,184 - 53,424,027 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	53,418,368 - 53,423,886 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	52,025,433 - 52,031,366 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	54,463,464 - 54,469,260 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	54,462,584 - 54,469,191 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	53,566,376 - 53,572,180 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	53,140,627 - 53,146,426 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	53,927,838 - 53,933,644 (-)	NCBI		UU_Cfam_GSD_1.0

Variants

Variants in PLAAT4
258 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007994839	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037999176	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000004882 ⟹ ENSCSAP00000003126

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	1	10,692,839 - 10,704,649 (-)	Ensembl

RefSeq Acc Id:

XM_007994839 ⟹ XP_007993030

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	1	10,695,127 - 10,704,564 (-)	NCBI
Vero_WHO_p1.0	NW_023666038	108,042,597 - 108,050,997 (-)	NCBI

Sequence:

show sequence

AGTCCTTTCATCTAGAGAAATAGCTCTCTTTTCAACAGTTGTCTCTCTTAAACAGTATTTAGTA
TTTGAATGAGGTTGAAACAGTGTCAAAAGGAAAGTAAAAGTGAAATTCTGTCTTTCAGCATAAA
AGCTGATCCACAAACAGCGGAGCACCAGACCTCACCTTGGCTTGGAGATGGCTTCGCCACAGCA
GGAGCCCAAACCGGGAGACCTGATTGAGATTTTCCGCCTTGGCTATGAGCACTGGGCCCTGTAT
ATAGGAGATGGCTACGTGATCCATCTGGCTCCTCAAGATGGGTACCCCGCGGCTAGCTCCCCCA
GTGCCTTCTCAGTCCCGGGCAGCATTGCAGTGGTGAAACAGGACCTCCTGAAAGATGTGCTGGA
AGGCTGTAACTATCGGGTCAACAACCGCTTGGACCGTAGGTACAAACCACTGCCCGTGGGGGTG
ATCATCAGTTCTGCCAAGGAGTTGGTTGGTCAGAAGATGAAGTACAGTATTGTGAGCAGGAACT
GTGAGCACTTTGTCACCAAGCTGAGATATGGCAGGTCCCACTGTCAACAGGTGGGAAATGCCGC
GGCTGAAGTCGGTGCGGTCGCGATGATTGCAGCGGCTGTTGCTGGATGCTCTTTGGCAATTGTG
AAATACCAAAAGTGACAGCCTGAAGCAGCCACAAAATCCTGTATTAGAAGCAGATGTGGGGGTC
CCAGTGGAGATGTGGGGGTCCCAGGCCTCCCCCACACCTCCAGCAGCCTGACCCTCGTGCTCTG
TCTCAGGCTGTCTCTAGATCCTTTCCTCTGTTTCCTTCTCTCGCTGGTGAAAGTATGATCTAAT
TGAAACAAGATTGAAGGATCAATAAACAGCCATCTGCCCCTTCAGAAAGGAA

hide sequence

RefSeq Acc Id:

XM_037999176 ⟹ XP_037855104

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666038	108,042,597 - 108,051,007 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_007993030	(Get FASTA)	NCBI Sequence Viewer
	XP_037855104	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000003126
	ENSCSAP00000003126.1

RefSeq Acc Id:	XP_007993030 ⟸ XM_007994839
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9R3D7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000003126 ⟸ ENSCSAT00000004882

RefSeq Acc Id:	XP_037855104 ⟸ XM_037999176
- Peptide Label:	isoform X1

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000006839	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000004882.1	UniProtKB/TrEMBL
Gene3D-CATH	endopeptidase domain like (from Nostoc punctiforme)	UniProtKB/TrEMBL
InterPro	H-rev107_PLA/AT	UniProtKB/TrEMBL
	LRAT_dom	UniProtKB/TrEMBL
KEGG Report	csab:103233706	UniProtKB/TrEMBL
NCBI Gene	PLAAT4	ENTREZGENE
PANTHER	HRAS-LIKE SUPPRESSOR - RELATED	UniProtKB/TrEMBL
	PTHR13943:SF36	UniProtKB/TrEMBL
Pfam	LRAT	UniProtKB/TrEMBL
PROSITE	LRAT	UniProtKB/TrEMBL
UniProt	A0A0D9R3D7	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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