ESF1 (ESF1 nucleolar pre-rRNA processing protein) - Rat Genome Database

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Gene: ESF1 (ESF1 nucleolar pre-rRNA processing protein) Chlorocebus sabaeus
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Symbol: ESF1
Name: ESF1 nucleolar pre-rRNA processing protein
RGD ID: 18414614
Description: ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN rRNA processing (inferred); ASSOCIATED WITH Breast Cancer, Familial (ortholog); cervical cancer (ortholog); colon adenocarcinoma (ortholog); FOUND IN nucleolus (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ESF1 homolog; ESF1 nucleolar pre-rRNA processing protein homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap1252,037,351 - 52,106,176 (+)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_0236660542,878,134 - 2,945,157 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.1242,600,989 - 42,670,600 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl242,601,007 - 42,668,874 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleolus  (IEA)
nucleus  (IEA)

Molecular Function
RNA binding  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ESF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap1252,037,351 - 52,106,176 (+)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_0236660542,878,134 - 2,945,157 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.1242,600,989 - 42,670,600 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl242,601,007 - 42,668,874 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
ESF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382013,714,325 - 13,784,919 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2013,714,322 - 13,785,409 (-)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh372013,694,972 - 13,765,565 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362013,642,969 - 13,713,532 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342013,642,968 - 13,713,532NCBI
Celera2013,765,027 - 13,835,578 (-)NCBICelera
Cytogenetic Map20p12.1NCBI
HuRef2013,649,375 - 13,720,216 (-)NCBIHuRef
CHM1_12013,694,965 - 13,765,524 (-)NCBICHM1_1
T2T-CHM13v2.02013,757,729 - 13,828,638 (-)NCBIT2T-CHM13v2.0
Esf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392139,961,800 - 140,012,498 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2139,961,791 - 140,012,490 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382140,119,881 - 140,170,558 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2140,119,883 - 140,170,564 (-)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv372139,945,617 - 139,996,294 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362139,811,322 - 139,861,999 (-)NCBIMGSCv36mm8
Celera2141,305,714 - 141,356,129 (-)NCBICelera
Cytogenetic Map2F3NCBI
cM Map269.2NCBI
Esf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83147,908,405 - 147,961,567 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3147,908,405 - 147,961,485 (-)EnsemblGRCr8
mRatBN7.23127,454,744 - 127,507,941 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3127,454,811 - 127,507,817 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3131,318,063 - 131,371,009 (-)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03139,902,158 - 139,955,105 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03137,605,302 - 137,658,246 (-)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd3145,937,488 - 145,990,436 (-)NCBI
Lyon_Normotensive3152,876,291 - 152,929,235 (-)NCBI
Lyon_Hypertensive3144,742,809 - 144,795,755 (-)NCBI
F344_StmMcwi3126,062,480 - 126,115,434 (-)NCBI
Rnor_6.03133,178,591 - 133,232,358 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3133,178,561 - 133,232,322 (-)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.03139,635,099 - 139,688,250 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43128,283,410 - 128,353,739 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3126,101,763 - 126,154,682 (-)NCBICelera
RGSC_v3.13128,189,731 - 128,257,244 (-)NCBI
Cytogenetic Map3q36-q41NCBI
Esf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541523,155,677 - 23,221,027 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_00495541523,156,521 - 23,221,027 (-)NCBIChiLan1.0ChiLan1.0
ESF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22114,608,655 - 14,679,172 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12014,605,486 - 14,676,003 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02013,680,818 - 13,751,249 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12013,666,156 - 13,734,004 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2013,666,703 - 13,734,004 (-)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
ESF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1248,873,230 - 8,938,592 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl248,874,834 - 8,937,096 (+)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha248,684,826 - 8,750,650 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0249,285,761 - 9,351,581 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl249,285,828 - 9,350,080 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1248,885,320 - 8,950,657 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0248,981,582 - 9,046,789 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0249,330,272 - 9,396,080 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Esf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap15163,026,933 - 163,099,602 (+)NCBImIctTri1.hap1
HiC_Itri_2NW_024408640157,593,651 - 157,665,934 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364856,024,628 - 6,100,606 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364856,025,090 - 6,097,328 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ESF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1722,418,885 - 22,480,224 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.11722,418,945 - 22,480,307 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21725,098,801 - 25,160,168 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Esf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474114,708,812 - 14,778,283 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_00462474114,707,599 - 14,777,989 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl1554,659,173 - 54,730,383 (+)Ensembl
Esf1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15119,421,243 - 119,473,672 (-)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1

Variants

.
Variants in ESF1
1507 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000009866   ⟹   ENSCSAP00000007974
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl242,601,007 - 42,668,874 (-)Ensembl
RefSeq Acc Id: XM_037984752   ⟹   XP_037840680
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
mChlSab1.0.hap1252,037,351 - 52,106,176 (+)NCBI
Vero_WHO_p1.0NW_0236660542,878,134 - 2,945,157 (-)NCBI
RefSeq Acc Id: XM_073008415   ⟹   XP_072864516
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
mChlSab1.0.hap1252,037,648 - 52,106,176 (+)NCBI
RefSeq Acc Id: XM_073008417   ⟹   XP_072864518
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
mChlSab1.0.hap1252,037,351 - 52,106,176 (+)NCBI
Protein Sequences
Protein RefSeqs XP_037840680 (Get FASTA)   NCBI Sequence Viewer  
  XP_072864516 (Get FASTA)   NCBI Sequence Viewer  
  XP_072864518 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007974.1
Ensembl Acc Id: ENSCSAP00000007974   ⟸   ENSCSAT00000009866
RefSeq Acc Id: XP_037840680   ⟸   XM_037984752
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RH85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_072864518   ⟸   XM_073008417
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RH85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_072864516   ⟸   XM_073008415
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RH85 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011777 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009866.1 UniProtKB/TrEMBL
InterPro Esf1 UniProtKB/TrEMBL
  NUC153 UniProtKB/TrEMBL
  RRM_ESF1 UniProtKB/TrEMBL
KEGG Report csab:103214463 UniProtKB/TrEMBL
NCBI Gene ESF1 ENTREZGENE
PANTHER ESF1 HOMOLOG UniProtKB/TrEMBL
  PTHR12202 UniProtKB/TrEMBL
Pfam NUC153 UniProtKB/TrEMBL
  RRM_ESF1 UniProtKB/TrEMBL
UniProt A0A0D9RH85 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-07-09 ESF1  ESF1 nucleolar pre-rRNA processing protein  ESF1  ESF1 nucleolar pre-rRNA processing protein homolog  Symbol and/or name change 5135510 APPROVED