ELMO2 (engulfment and cell motility 2) - Rat Genome Database

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Gene: ELMO2 (engulfment and cell motility 2) Chlorocebus sabaeus
Analyze
Symbol: ELMO2
Name: engulfment and cell motility 2
RGD ID: 18385241
Description: ENCODES a protein that exhibits receptor tyrosine kinase binding (inferred); SH3 domain binding (inferred); INVOLVED IN actin filament organization (inferred); apoptotic process (inferred); cell chemotaxis (inferred); ASSOCIATED WITH adenosine deaminase deficiency (ortholog); focal epilepsy (ortholog); genetic disease (ortholog); FOUND IN cytosol (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: engulfment and cell motility protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1217,477,425 - 17,518,814 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl217,489,658 - 17,518,843 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605066,111,817 - 66,152,993 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ELMO2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1217,477,425 - 17,518,814 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl217,489,658 - 17,518,843 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605066,111,817 - 66,152,993 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ELMO2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382046,366,050 - 46,406,615 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2046,366,050 - 46,432,985 (-)EnsemblGRCh38hg38GRCh38
GRCh372044,994,689 - 45,035,254 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362044,428,096 - 44,468,678 (-)NCBINCBI36Build 36hg18NCBI36
Build 342044,428,097 - 44,468,678NCBI
Celera2041,706,103 - 41,746,680 (-)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2041,735,582 - 41,776,159 (-)NCBIHuRef
CHM1_12044,897,310 - 44,937,893 (-)NCBICHM1_1
T2T-CHM13v2.02048,102,079 - 48,142,641 (-)NCBIT2T-CHM13v2.0
Elmo2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392165,129,951 - 165,168,421 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2165,129,951 - 165,168,399 (-)EnsemblGRCm39 Ensembl
GRCm382165,288,031 - 165,326,479 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2165,288,031 - 165,326,479 (-)EnsemblGRCm38mm10GRCm38
MGSCv372165,113,531 - 165,151,979 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362164,979,236 - 165,017,684 (-)NCBIMGSCv36mm8
Celera2171,230,425 - 171,268,832 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.53NCBI
Elmo2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83174,442,965 - 174,716,723 (-)NCBIGRCr8
mRatBN7.23154,023,661 - 154,061,259 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3154,023,661 - 154,061,185 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3157,832,343 - 157,869,836 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03166,331,325 - 166,368,817 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03164,072,707 - 164,110,271 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03161,812,474 - 161,850,006 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,812,474 - 162,003,588 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03167,997,379 - 168,034,881 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43156,328,613 - 156,366,106 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13156,235,766 - 156,272,148 (-)NCBI
Celera3152,622,864 - 152,660,341 (-)NCBICelera
Cytogenetic Map3q42NCBI
Elmo2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544510,943,780 - 10,982,778 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544510,943,838 - 10,982,653 (+)NCBIChiLan1.0ChiLan1.0
ELMO2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22152,105,760 - 52,146,401 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12052,098,866 - 52,139,419 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02042,702,930 - 42,770,211 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12043,788,090 - 43,855,542 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2043,788,090 - 43,828,693 (-)Ensemblpanpan1.1panPan2
ELMO2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12433,599,108 - 33,639,096 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2433,600,444 - 33,626,665 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.02434,308,676 - 34,348,685 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2434,308,692 - 34,348,682 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12433,566,624 - 33,606,614 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02433,682,475 - 33,722,458 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02434,221,642 - 34,261,691 (-)NCBIUU_Cfam_GSD_1.0
Elmo2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640191,252,539 - 191,291,890 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365146,706,236 - 6,746,006 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365146,706,236 - 6,745,538 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELMO2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1748,526,700 - 48,567,657 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11748,526,692 - 48,567,665 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21754,169,990 - 54,187,609 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Elmo2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247908,228,259 - 8,267,179 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247908,228,234 - 8,266,585 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ELMO2
647 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000012860   ⟹   ENSCSAP00000010883
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl217,489,658 - 17,518,843 (+)Ensembl
RefSeq Acc Id: XM_008015310   ⟹   XP_008013501
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1217,477,425 - 17,518,814 (+)NCBI
Vero_WHO_p1.0NW_02366605066,111,817 - 66,152,993 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037982705   ⟹   XP_037838633
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605066,111,843 - 66,152,993 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008013501 (Get FASTA)   NCBI Sequence Viewer  
  XP_037838633 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000010883.1
RefSeq Acc Id: XP_008013501   ⟸   XM_008015310
- UniProtKB: A0A0D9RQJ4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000010883   ⟸   ENSCSAT00000012860
RefSeq Acc Id: XP_037838633   ⟸   XM_037982705
- UniProtKB: A0A0D9RQJ4 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000014771 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000012860.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  6.10.250.810 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  DUF3361 UniProtKB/TrEMBL
  ELMO_dom UniProtKB/TrEMBL
  ELMO_domain-containing UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
KEGG Report csab:103244982 UniProtKB/TrEMBL
NCBI Gene ELMO2 ENTREZGENE
PANTHER ENGULFMENT AND CELL MOTILITY UniProtKB/TrEMBL
  PTHR12771:SF8 UniProtKB/TrEMBL
Pfam DUF3361 UniProtKB/TrEMBL
  ELMO_CED12 UniProtKB/TrEMBL
  PH_12 UniProtKB/TrEMBL
PROSITE ELMO UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48371 UniProtKB/TrEMBL
UniProt A0A0D9RQJ4 ENTREZGENE, UniProtKB/TrEMBL