RHOF (ras homolog family member F, filopodia associated) - Rat Genome Database

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Gene: RHOF (ras homolog family member F, filopodia associated) Chlorocebus sabaeus
Analyze
Symbol: RHOF
Name: ras homolog family member F, filopodia associated
RGD ID: 18381189
Description: ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); INVOLVED IN actin filament organization (inferred); small GTPase-mediated signal transduction (inferred); ASSOCIATED WITH immunodeficiency 9 (ortholog); short chain acyl-CoA dehydrogenase deficiency (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras homolog family member F (in filopodia); rho-related GTP-binding protein RhoF
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111117,147,282 - 117,163,358 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11117,148,143 - 117,163,604 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037127,802,931 - 127,822,518 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RHOF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111117,147,282 - 117,163,358 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11117,148,143 - 117,163,604 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037127,802,931 - 127,822,518 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RHOF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812121,777,754 - 121,793,688 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12121,777,754 - 121,803,403 (-)EnsemblGRCh38hg38GRCh38
GRCh3712122,215,660 - 122,231,594 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612120,700,043 - 120,715,977 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412120,678,379 - 120,694,314NCBI
Celera12121,851,908 - 121,867,844 (-)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12119,227,850 - 119,243,788 (-)NCBIHuRef
CHM1_112122,183,408 - 122,199,363 (-)NCBICHM1_1
T2T-CHM13v2.012121,774,422 - 121,790,359 (-)NCBIT2T-CHM13v2.0
Rhof
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395123,256,243 - 123,270,692 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5123,241,107 - 123,270,755 (-)EnsemblGRCm39 Ensembl
GRCm385123,118,180 - 123,141,808 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5123,103,044 - 123,132,692 (-)EnsemblGRCm38mm10GRCm38
MGSCv375123,568,189 - 123,582,638 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365123,363,661 - 123,393,013 (-)NCBIMGSCv36mm8
Celera5120,213,155 - 120,227,597 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map562.77NCBI
Rhof
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81239,082,413 - 39,107,528 (+)NCBIGRCr8
mRatBN7.21233,422,375 - 33,446,689 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1233,431,280 - 33,446,703 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1234,609,866 - 34,624,919 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01235,221,237 - 35,236,290 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01234,273,106 - 34,288,162 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01238,879,763 - 38,894,095 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1238,880,377 - 38,894,582 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01240,778,266 - 40,792,798 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41234,598,537 - 34,599,106 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1235,111,762 - 35,127,795 (+)NCBICelera
Cytogenetic Map12q16NCBI
Rhof
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554826,631,666 - 6,643,634 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554826,631,327 - 6,643,634 (+)NCBIChiLan1.0ChiLan1.0
RHOF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210129,867,497 - 129,884,039 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112129,863,257 - 129,880,286 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012119,381,412 - 119,397,229 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112122,751,751 - 122,766,800 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12122,751,751 - 122,766,800 (-)Ensemblpanpan1.1panPan2
RHOF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1267,476,753 - 7,489,427 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl267,477,766 - 7,491,160 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha267,637,156 - 7,649,745 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0267,729,301 - 7,741,890 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl267,729,300 - 7,746,231 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1267,661,165 - 7,673,754 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0267,751,513 - 7,764,100 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0267,707,438 - 7,720,028 (+)NCBIUU_Cfam_GSD_1.0
Rhof
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118156,845,544 - 156,867,546 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365582,621,689 - 2,633,853 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365582,611,847 - 2,633,878 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RHOF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1430,896,114 - 30,908,419 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11430,886,053 - 30,908,048 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21432,691,259 - 32,713,248 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Rhof
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474722,162,985 - 22,174,066 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474722,163,533 - 22,174,080 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RHOF
334 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000000207   ⟹   ENSCSAP00000015846
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl11117,148,143 - 117,163,604 (-)Ensembl
RefSeq Acc Id: XM_008005006   ⟹   XP_008003197
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.111117,147,282 - 117,163,358 (-)NCBI
Vero_WHO_p1.0NW_023666037127,802,931 - 127,822,518 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008005007   ⟹   XP_008003198
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.111117,147,282 - 117,163,358 (-)NCBI
Vero_WHO_p1.0NW_023666037127,802,931 - 127,822,518 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037995893   ⟹   XP_037851821
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037127,817,088 - 127,822,518 (+)NCBI
RefSeq Acc Id: XM_037995902   ⟹   XP_037851830
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037127,817,193 - 127,822,518 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008003197 (Get FASTA)   NCBI Sequence Viewer  
  XP_008003198 (Get FASTA)   NCBI Sequence Viewer  
  XP_037851821 (Get FASTA)   NCBI Sequence Viewer  
  XP_037851830 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015846
  ENSCSAP00000015846.1
RefSeq Acc Id: XP_008003198   ⟸   XM_008005007
- Peptide Label: isoform X4
- UniProtKB: A0A0D9S4Q7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008003197   ⟸   XM_008005006
- Peptide Label: isoform X2
Ensembl Acc Id: ENSCSAP00000015846   ⟸   ENSCSAT00000000207
RefSeq Acc Id: XP_037851821   ⟸   XM_037995893
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037851830   ⟸   XM_037995902
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002190 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000207.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
  Small_GTPase_Rho UniProtKB/TrEMBL
NCBI Gene RHOF ENTREZGENE
PANTHER PTHR24072 UniProtKB/TrEMBL
  RHO-RELATED GTP-BINDING PROTEIN RHOF UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0D9S4Q7 ENTREZGENE, UniProtKB/TrEMBL