SYS1-DBNDD2 (SYS1-DBNDD2 readthrough (NMD candidate))

Advanced Search (OLGA)

Gene: SYS1-DBNDD2 (SYS1-DBNDD2 readthrough (NMD candidate)) Homo sapiens

Analyze

Symbol:

SYS1-DBNDD2

Name:

SYS1-DBNDD2 readthrough (NMD candidate)

RGD ID:

1642399

HGNC Page

HGNC:33535

Description:

Predicted to be involved in protein transport. Predicted to be located in Golgi membrane.

Type:

ncrna (Ensembl: protein-coding)

RefSeq Status:

VALIDATED

Previously known as:

C20orf169-DBNDD2

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	45,363,169 - 45,410,610 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	45,363,200 - 45,410,610 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	43,991,809 - 44,039,250 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	43,425,254 - 43,472,661 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	20	40,700,358 - 40,747,756 (+)	NCBI		Celera
Cytogenetic Map	20	q13.12	NCBI
HuRef	20	40,733,312 - 40,780,742 (+)	NCBI		HuRef
CHM1_1	20	43,894,350 - 43,941,787 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	47,099,044 - 47,146,472 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

acrylamide (EXP)

aflatoxin B1 (EXP)

doxorubicin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein transport (IEA)

Cellular Component

Golgi apparatus (IEA)

Golgi membrane (IEA)

membrane (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11181995	PMID:12477932	PMID:20967262

Genomics

Variants

Variants in SYS1-DBNDD2
54 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
NM_018478.3(DBNDD2):c.139C>T (p.Arg47Cys)	single nucleotide variant	not specified [RCV004264456]	Chr20:45406590 [GRCh38] Chr20:44035230 [GRCh37] Chr20:20q13.12	uncertain significance
NM_001197129.1(SYS1):c.252C>T (p.Phe84=)	single nucleotide variant	Malignant melanoma [RCV000063754]	Chr20:45366896 [GRCh38] Chr20:43995536 [GRCh37] Chr20:43428950 [NCBI36] Chr20:20q13.12	not provided
GRCh38/hg38 20p13-q13.33(chr20:99557-64277321)x3	copy number gain	See cases [RCV000135859]	Chr20:99557..64277321 [GRCh38] Chr20:80198..62908674 [GRCh37] Chr20:28198..62379118 [NCBI36] Chr20:20p13-q13.33	pathogenic
GRCh38/hg38 20q13.12(chr20:45304962-45374661)x3	copy number gain	See cases [RCV000135905]	Chr20:45304962..45374661 [GRCh38] Chr20:43933602..44003301 [GRCh37] Chr20:43367016..43436715 [NCBI36] Chr20:20q13.12	benign
GRCh38/hg38 20q11.22-13.12(chr20:35237946-47631818)x1	copy number loss	See cases [RCV000140816]	Chr20:35237946..47631818 [GRCh38] Chr20:33825749..46260562 [GRCh37] Chr20:33289165..45693969 [NCBI36] Chr20:20q11.22-13.12	pathogenic
GRCh38/hg38 20q13.12-13.33(chr20:44787704-64277321)x3	copy number gain	See cases [RCV000053035]	Chr20:44787704..64277321 [GRCh38] Chr20:43416345..62908674 [GRCh37] Chr20:42849759..62379118 [NCBI36] Chr20:20q13.12-13.33	pathogenic
NM_001048225.4(DBNDD2):c.55C>T (p.Arg19Trp)	single nucleotide variant	not specified [RCV004315218]	Chr20:45408522 [GRCh38] Chr20:44037162 [GRCh37] Chr20:20q13.12	uncertain significance
NM_033542.4(SYS1):c.5C>T (p.Ala2Val)	single nucleotide variant	not specified [RCV004319861]	Chr20:45363536 [GRCh38] Chr20:43992176 [GRCh37] Chr20:20q13.12	uncertain significance
NM_033542.4(SYS1):c.422C>T (p.Thr141Met)	single nucleotide variant	not specified [RCV004304074]	Chr20:45367066 [GRCh38] Chr20:43995706 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.122C>T (p.Thr41Met)	single nucleotide variant	not specified [RCV004292069]	Chr20:45377540 [GRCh38] Chr20:44006180 [GRCh37] Chr20:20q13.12	likely benign
NM_018478.3(DBNDD2):c.145C>T (p.Arg49Trp)	single nucleotide variant	not specified [RCV004332009]	Chr20:45406596 [GRCh38] Chr20:44035236 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.599A>G (p.Lys200Arg)	single nucleotide variant	not specified [RCV004677255]	Chr20:45375208 [GRCh38] Chr20:44003848 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.677T>C (p.Met226Thr)	single nucleotide variant	not specified [RCV004687592]	Chr20:45375130 [GRCh38] Chr20:44003770 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.604C>G (p.Leu202Val)	single nucleotide variant	not specified [RCV004687594]	Chr20:45375203 [GRCh38] Chr20:44003843 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.314G>A (p.Cys105Tyr)	single nucleotide variant	not specified [RCV004677253]	Chr20:45375493 [GRCh38] Chr20:44004133 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.746T>C (p.Met249Thr)	single nucleotide variant	not specified [RCV004677254]	Chr20:45375061 [GRCh38] Chr20:44003701 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.785C>T (p.Thr262Met)	single nucleotide variant	not specified [RCV004677256]	Chr20:45373995 [GRCh38] Chr20:44002635 [GRCh37] Chr20:20q13.12	likely benign
NM_014477.3(TP53TG5):c.337A>G (p.Lys113Glu)	single nucleotide variant	not specified [RCV004298720]	Chr20:45375470 [GRCh38] Chr20:44004110 [GRCh37] Chr20:20q13.12	uncertain significance
NM_001048225.4(DBNDD2):c.302T>C (p.Leu101Pro)	single nucleotide variant	not specified [RCV004293358]	Chr20:45409956 [GRCh38] Chr20:44038596 [GRCh37] Chr20:20q13.12	uncertain significance
NM_018478.3(DBNDD2):c.76G>A (p.Ala26Thr)	single nucleotide variant	not specified [RCV004151526]	Chr20:45406527 [GRCh38] Chr20:44035167 [GRCh37] Chr20:20q13.12	uncertain significance
NM_033542.4(SYS1):c.193C>T (p.Leu65Phe)	single nucleotide variant	not specified [RCV004092591]	Chr20:45365649 [GRCh38] Chr20:43994289 [GRCh37] Chr20:20q13.12	uncertain significance
NM_001048225.2(DBNDD2):c.83G>A (p.Ser28Asn)	single nucleotide variant	not specified [RCV004080658]	Chr20:45408244 [GRCh38] Chr20:44036884 [GRCh37] Chr20:20q13.12	uncertain significance
NM_033542.4(SYS1):c.22T>C (p.Tyr8His)	single nucleotide variant	not specified [RCV004158094]	Chr20:45363553 [GRCh38] Chr20:43992193 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.865T>C (p.Tyr289His)	single nucleotide variant	not specified [RCV004160341]	Chr20:45373915 [GRCh38] Chr20:44002555 [GRCh37] Chr20:20q13.12	uncertain significance
NM_033542.4(SYS1):c.8G>C (p.Gly3Ala)	single nucleotide variant	not specified [RCV004207400]	Chr20:45363539 [GRCh38] Chr20:43992179 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.712C>T (p.Arg238Cys)	single nucleotide variant	not specified [RCV004129312]	Chr20:45375095 [GRCh38] Chr20:44003735 [GRCh37] Chr20:20q13.12	likely benign
NM_018478.3(DBNDD2):c.115C>G (p.His39Asp)	single nucleotide variant	not specified [RCV004225121]	Chr20:45406566 [GRCh38] Chr20:44035206 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.575A>G (p.Asn192Ser)	single nucleotide variant	not specified [RCV004133379]	Chr20:45375232 [GRCh38] Chr20:44003872 [GRCh37] Chr20:20q13.12	uncertain significance
NM_033542.4(SYS1):c.19A>T (p.Ser7Cys)	single nucleotide variant	not specified [RCV004157061]	Chr20:45363550 [GRCh38] Chr20:43992190 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.437C>T (p.Ala146Val)	single nucleotide variant	not specified [RCV004206482]	Chr20:45375370 [GRCh38] Chr20:44004010 [GRCh37] Chr20:20q13.12	uncertain significance
NM_001048225.4(DBNDD2):c.473G>C (p.Gly158Ala)	single nucleotide variant	not specified [RCV004088618]	Chr20:45410127 [GRCh38] Chr20:44038767 [GRCh37] Chr20:20q13.12	uncertain significance
NM_001048225.4(DBNDD2):c.378C>A (p.Asn126Lys)	single nucleotide variant	not specified [RCV004151082]	Chr20:45410032 [GRCh38] Chr20:44038672 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.697C>T (p.Arg233Cys)	single nucleotide variant	not specified [RCV004228428]	Chr20:45375110 [GRCh38] Chr20:44003750 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.113G>A (p.Arg38His)	single nucleotide variant	not specified [RCV004187891]	Chr20:45377549 [GRCh38] Chr20:44006189 [GRCh37] Chr20:20q13.12	uncertain significance
NM_033542.4(SYS1):c.461C>T (p.Ser154Phe)	single nucleotide variant	not specified [RCV004094709]	Chr20:45367105 [GRCh38] Chr20:43995745 [GRCh37] Chr20:20q13.12	uncertain significance
NM_001048225.4(DBNDD2):c.364G>T (p.Asp122Tyr)	single nucleotide variant	not specified [RCV004078349]	Chr20:45410018 [GRCh38] Chr20:44038658 [GRCh37] Chr20:20q13.12	uncertain significance
NM_001048225.4(DBNDD2):c.365A>C (p.Asp122Ala)	single nucleotide variant	not specified [RCV004078350]	Chr20:45410019 [GRCh38] Chr20:44038659 [GRCh37] Chr20:20q13.12	uncertain significance
NM_001048225.4(DBNDD2):c.281T>C (p.Met94Thr)	single nucleotide variant	not specified [RCV004245805]	Chr20:45409935 [GRCh38] Chr20:44038575 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.173G>A (p.Arg58Gln)	single nucleotide variant	not specified [RCV004168383]	Chr20:45377293 [GRCh38] Chr20:44005933 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.733G>A (p.Ala245Thr)	single nucleotide variant	not specified [RCV004118417]	Chr20:45375074 [GRCh38] Chr20:44003714 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.553A>C (p.Ile185Leu)	single nucleotide variant	not specified [RCV004166333]	Chr20:45375254 [GRCh38] Chr20:44003894 [GRCh37] Chr20:20q13.12	uncertain significance
NM_001048225.4(DBNDD2):c.-5C>A	single nucleotide variant	not specified [RCV004228422]	Chr20:45408463 [GRCh38] Chr20:44037103 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.73G>A (p.Glu25Lys)	single nucleotide variant	not specified [RCV004304458]	Chr20:45377589 [GRCh38] Chr20:44006229 [GRCh37] Chr20:20q13.12	likely benign
NM_001048225.4(DBNDD2):c.-146C>T	single nucleotide variant	not specified [RCV004253593]	Chr20:45408322 [GRCh38] Chr20:44036962 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.650G>A (p.Arg217Gln)	single nucleotide variant	not specified [RCV004265097]	Chr20:45375157 [GRCh38] Chr20:44003797 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.553A>G (p.Ile185Val)	single nucleotide variant	not specified [RCV004260018]	Chr20:45375254 [GRCh38] Chr20:44003894 [GRCh37] Chr20:20q13.12	likely benign
NM_014477.3(TP53TG5):c.426A>T (p.Lys142Asn)	single nucleotide variant	not specified [RCV004283218]	Chr20:45375381 [GRCh38] Chr20:44004021 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.671G>A (p.Arg224Lys)	single nucleotide variant	not specified [RCV004278302]	Chr20:45375136 [GRCh38] Chr20:44003776 [GRCh37] Chr20:20q13.12	uncertain significance
NM_033542.4(SYS1):c.5C>A (p.Ala2Glu)	single nucleotide variant	not specified [RCV004327894]	Chr20:45363536 [GRCh38] Chr20:43992176 [GRCh37] Chr20:20q13.12	uncertain significance
NM_001048225.2(DBNDD2):c.12G>C (p.Trp4Cys)	single nucleotide variant	not specified [RCV004343488]	Chr20:45408173 [GRCh38] Chr20:44036813 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.542G>T (p.Gly181Val)	single nucleotide variant	not specified [RCV004335159]	Chr20:45375265 [GRCh38] Chr20:44003905 [GRCh37] Chr20:20q13.12	uncertain significance
NM_001048225.4(DBNDD2):c.431C>T (p.Ser144Leu)	single nucleotide variant	not specified [RCV004363996]	Chr20:45410085 [GRCh38] Chr20:44038725 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.85C>G (p.Pro29Ala)	single nucleotide variant	not specified [RCV004359464]	Chr20:45377577 [GRCh38] Chr20:44006217 [GRCh37] Chr20:20q13.12	uncertain significance
NM_033542.4(SYS1):c.100C>T (p.Leu34=)	single nucleotide variant	not provided [RCV003440413]	Chr20:45363631 [GRCh38] Chr20:43992271 [GRCh37] Chr20:20q13.12	likely benign
NM_033542.4(SYS1):c.345G>A (p.Ser115=)	single nucleotide variant	not provided [RCV003440414]	Chr20:45366989 [GRCh38] Chr20:43995629 [GRCh37] Chr20:20q13.12	likely benign
NM_001048225.4(DBNDD2):c.-15C>A	single nucleotide variant	not specified [RCV004373022]	Chr20:45408453 [GRCh38] Chr20:44037093 [GRCh37] Chr20:20q13.12	uncertain significance
NM_001048225.4(DBNDD2):c.325G>A (p.Asp109Asn)	single nucleotide variant	not specified [RCV004373024]	Chr20:45409979 [GRCh38] Chr20:44038619 [GRCh37] Chr20:20q13.12	uncertain significance
NM_001048225.4(DBNDD2):c.344C>A (p.Thr115Asn)	single nucleotide variant	not specified [RCV004373025]	Chr20:45409998 [GRCh38] Chr20:44038638 [GRCh37] Chr20:20q13.12	uncertain significance
NM_018478.3(DBNDD2):c.29T>G (p.Leu10Trp)	single nucleotide variant	not specified [RCV004373023]	Chr20:45406480 [GRCh38] Chr20:44035120 [GRCh37] Chr20:20q13.12	uncertain significance
NM_014477.3(TP53TG5):c.488C>T (p.Ser163Leu)	single nucleotide variant	not specified [RCV004468324]	Chr20:45375319 [GRCh38] Chr20:44003959 [GRCh37] Chr20:20q13.12	uncertain significance
NM_033542.4(SYS1):c.11A>T (p.Gln4Leu)	single nucleotide variant	not specified [RCV004463859]	Chr20:45363542 [GRCh38] Chr20:43992182 [GRCh37] Chr20:20q13.12	uncertain significance
NM_033542.4(SYS1):c.344C>T (p.Ser115Leu)	single nucleotide variant	not specified [RCV004463860]	Chr20:45366988 [GRCh38] Chr20:43995628 [GRCh37] Chr20:20q13.12	uncertain significance
NM_033542.4(SYS1):c.418C>T (p.Arg140Trp)	single nucleotide variant	not specified [RCV004463861]	Chr20:45367062 [GRCh38] Chr20:43995702 [GRCh37] Chr20:20q13.12	uncertain significance
NM_018478.3(DBNDD2):c.109C>T (p.Leu37Phe)	single nucleotide variant	not specified [RCV004608837]	Chr20:45406560 [GRCh38] Chr20:44035200 [GRCh37] Chr20:20q13.12	uncertain significance
NM_033542.4(SYS1):c.80A>G (p.Tyr27Cys)	single nucleotide variant	not specified [RCV004670942]	Chr20:45363611 [GRCh38] Chr20:43992251 [GRCh37] Chr20:20q13.12	uncertain significance

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	1274
Count of miRNA genes:	541
Interacting mature miRNAs:	625
Transcripts:	ENST00000419593, ENST00000452133, ENST00000458187, ENST00000475242
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCh38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
407180741	GWAS829717_H	FEV/FVC ratio QTL GWAS829717 (human)		5e-11	FEV/FVC ratio	forced expiratory volume to forced vital capacity ratio (CMO:0000241)	20	45372675	45372676	Human
1300007	BP29_H	Blood pressure QTL 29 (human)			Blood pressure	hypertension susceptibility	20	36536005	62536005	Human
407230621	GWAS879597_H	bone density QTL GWAS879597 (human)		1e-300	bone mineral mass (VT:0005007)	bone mineral density (CMO:0001226)	20	45409402	45409403	Human

Markers in Region

WI-16033

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	20	44,005,302 - 44,005,409	UniSTS	GRCh37
Build 36	20	43,438,716 - 43,438,823	RGD	NCBI36
Celera	20	40,713,816 - 40,713,923	RGD
Cytogenetic Map	20	q13.12	UniSTS
HuRef	20	40,746,798 - 40,746,905	UniSTS
GeneMap99-GB4 RH Map	20	237.11	UniSTS
GeneMap99-GB4 RH Map	20	254.92	UniSTS
Whitehead-RH Map	20	292.5	UniSTS

RH75592

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	20	43,997,586 - 43,997,807	UniSTS	GRCh37
Build 36	20	43,431,000 - 43,431,221	RGD	NCBI36
Celera	20	40,706,106 - 40,706,327	RGD
Cytogenetic Map	20	q13.12	UniSTS
HuRef	20	40,739,091 - 40,739,312	UniSTS

RH18508

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	20	43,996,474 - 43,996,574	UniSTS	GRCh37
Build 36	20	43,429,888 - 43,429,988	RGD	NCBI36
Celera	20	40,704,994 - 40,705,094	RGD
Cytogenetic Map	20	q13.12	UniSTS
HuRef	20	40,737,979 - 40,738,079	UniSTS
GeneMap99-GB4 RH Map	20	254.92	UniSTS

RH44476

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	20	43,997,677 - 43,997,816	UniSTS	GRCh37
Build 36	20	43,431,091 - 43,431,230	RGD	NCBI36
Celera	20	40,706,197 - 40,706,336	RGD
Cytogenetic Map	20	q13.12	UniSTS
HuRef	20	40,739,182 - 40,739,321	UniSTS
GeneMap99-GB4 RH Map	20	255.13	UniSTS

G19851

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	20	44,038,917 - 44,039,123	UniSTS	GRCh37
Build 36	20	43,472,331 - 43,472,537	RGD	NCBI36
Celera	20	40,747,426 - 40,747,632	RGD
Cytogenetic Map	20	q13.12	UniSTS
HuRef	20	40,780,409 - 40,780,615	UniSTS

A002A22

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	20	44,038,917 - 44,039,123	UniSTS	GRCh37
Build 36	20	43,472,331 - 43,472,537	RGD	NCBI36
Celera	20	40,747,426 - 40,747,632	RGD
Cytogenetic Map	20	q13.12	UniSTS
HuRef	20	40,780,409 - 40,780,615	UniSTS
GeneMap99-GB4 RH Map	20	255.3	UniSTS

STS-Z40239

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	20	44,039,150 - 44,039,218	UniSTS	GRCh37
Build 36	20	43,472,564 - 43,472,632	RGD	NCBI36
Celera	20	40,747,659 - 40,747,727	RGD
Cytogenetic Map	20	q13.12	UniSTS
HuRef	20	40,780,642 - 40,780,710	UniSTS
GeneMap99-GB4 RH Map	20	236.28	UniSTS
NCBI RH Map	20	483.7	UniSTS

MARC_12165-12166:1004710367:1

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	20	43,994,287 - 43,995,576	UniSTS	GRCh37
Build 36	20	43,427,701 - 43,428,990	RGD	NCBI36
Celera	20	40,702,807 - 40,704,096	RGD
HuRef	20	40,735,792 - 40,737,081	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	pharyngeal arch	renal system	reproductive system	respiratory system	sensory system	visual system
211	1	35	456	231	565	5	163	411	166	292	1050	495	53	171	1	322	317	374	12	1

Sequence

Nucleotide Sequences


RefSeq Transcripts	NR_003189	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AL021578	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC023562	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BI199175	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471077	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068258	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DN994280	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000419593 ⟹ ENSP00000456116

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	20	45,363,200 - 45,410,610 (+)	Ensembl

Ensembl Acc Id:

ENST00000452133 ⟹ ENSP00000457650

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	20	45,363,510 - 45,410,068 (+)	Ensembl

Ensembl Acc Id:

ENST00000458187 ⟹ ENSP00000457768

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	20	45,363,502 - 45,409,997 (+)	Ensembl

Ensembl Acc Id:

ENST00000475242

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	20	45,363,216 - 45,410,007 (+)	Ensembl

RefSeq Acc Id:

NR_003189

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	20	45,363,169 - 45,410,610 (+)	NCBI
GRCh37	20	43,991,809 - 44,039,250 (+)	ENTREZGENE
Build 36	20	43,425,254 - 43,472,661 (+)	NCBI Archive
Celera	20	40,700,358 - 40,747,756 (+)	RGD
HuRef	20	40,733,312 - 40,780,742 (+)	ENTREZGENE
CHM1_1	20	43,894,350 - 43,941,787 (+)	NCBI
T2T-CHM13v2.0	20	47,099,044 - 47,146,472 (+)	NCBI

Sequence:

show sequence

CCGCTCCTGCCGCCGTGGTCGCTGGAGCTTTGCCTCTCTAGGCCGGCAGCGCCTCTCCTCCATG
GTCCTGTCTGTCAGCGCTGTTTTGGGAGCCCGCCGGTGAGGCCGGGCCACGCTCAGACACTTCG
ATCGTCGAGTCTGTCACTGGGCATGGCGGGTCAGTTCCGCAGCTACGTGTGGGACCCGCTGCTG
ATCCTGTCGCAGATCGTCCTCATGCAGACCGTGTATTACGGCTCGCTGGGCCTGTGGCTGGCGC
TGGTGGACGGGCTAGTGCGAAGCAGCCCCTCGCTGGACCAGATGTTCGACGCCGAGATCCTGGG
CTTTTCCACCCCTCCAGGCCGGCTCTCCATGATGTCCTTCATCCTCAACGCCCTCACCTGGAGC
TGACATGGACCCAAATCCTCGGGCCGCCCTGGAGCGCCAGCAGCTCCGCCTTCGGGAGCGGCAA
AAATTCTTCGAGGACATTTTACAGCCAGAGACAGAGTTTGTCTTTCCTCTGTCCCATCTGCATC
TCGAGTCGCAGAGACCCCCCATAGGTAGTATCTCATCCATGGAAGTGAATGTGGACACACTGGA
GCAAGTAGAACTTATTGACCTTGGGGACCCGGATGCAGCAGATGTGTTCTTGCCTTGCGAAGAT
CCTCCACCAACCCCCCAGTCGTCTGGGATGGACAACCATTTGGAGGAGCTGAGCCTGCCGGTGC
CTACATCAGACAGGACCACATCTAGGACCTCCTCCTCCTCCTCCTCCGACTCCTCCACCAACCT
GCATAGCCCAAATCCAAGTGATGATGGAGCAGATACGCCCTTGGCACAGTCGGATGAAGAGGAG
GAAAGGGGTGATGGAGGGGCAGAGCCTGGAGCCTGCAGCTAGCAGTGGGCCCCTGCCTACAGAC
TGACCACGCTGGCTATTCTCCACATGAGACCACAGGCCCAGCCAGAGCCTGTCGGGAGAAGACC
AGACTCTTTACTTGCAGTAGGCACCAGAGGTGGGAAGGATGGTGGGATTGTGTACCTTTCTAAG
AATTAACCCTCTCCTGCTTTACTGCTAATTTTTTCCTGCTGCAACCCTCCCACCAGTTTTTGGC
TTACTCCTGAGATATGATTTGCAAATGAGGAGAGAGAAGATGAGGTTGGACAAGATGCCACTGC
TTTTCTTAGCACTCTTCCCTCCCCTAAACCATCCCGTAGTCTTCTAATACAGTCTCTCAGACAA
GTGTCTCTAGATGGATGTGAACTCCTTAACTCATCAAGTAAGGTGGTACTCAAGCCATGCTGCC
TCCTTACATCCTTTTTGGAACAGAGCACGGTATAAATAATAAACTAATAATAATATGCCAACCA

hide sequence

Protein Sequences


GenBank Protein	EAW75855	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000456116.1
	ENSP00000457650.1
	ENSP00000457768.1

Ensembl Acc Id:

ENSP00000457650 ⟸ ENST00000452133

Ensembl Acc Id:

ENSP00000456116 ⟸ ENST00000419593

Ensembl Acc Id:

ENSP00000457768 ⟸ ENST00000458187

Additional Information

External Database Links

Database	Acc Id	Source(s)
COSMIC	SYS1-DBNDD2	COSMIC
Ensembl Genes	ENSG00000254806	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENST00000419593	ENTREZGENE
	ENST00000419593.5	UniProtKB/TrEMBL
	ENST00000452133.1	UniProtKB/TrEMBL
	ENST00000458187.5	UniProtKB/TrEMBL
GTEx	ENSG00000254806	GTEx
HGNC ID	HGNC:33535	ENTREZGENE
Human Proteome Map	SYS1-DBNDD2	Human Proteome Map
InterPro	Integral_membrane_SYS1-rel	UniProtKB/TrEMBL
NCBI Gene	767557	ENTREZGENE
PANTHER	PROTEIN SYS1 HOMOLOG	UniProtKB/TrEMBL
	PTHR12952	UniProtKB/TrEMBL
Pfam	SYS1	UniProtKB/TrEMBL
PharmGKB	PA162405132	PharmGKB
RNAcentral	URS000075D296	RNACentral
UniProt	F2Z2A3_HUMAN	UniProtKB/TrEMBL
	H3BUS1_HUMAN	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-05-14	SYS1-DBNDD2	SYS1-DBNDD2 readthrough (NMD candidate)		SYS1-DBNDD2 readthrough (non-protein coding)	Symbol and/or name change	5135510	APPROVED
2012-05-29	SYS1-DBNDD2	SYS1-DBNDD2 readthrough (non-protein coding)	SYS1-DBNDD2	SYS1-DBNDD2 readthrough	Symbol and/or name change	5135510	APPROVED
2011-09-01	SYS1-DBNDD2	SYS1-DBNDD2 readthrough	SYS1-DBNDD2	SYS1-DBNDD2 readthrough	Symbol and/or name change	5135510	APPROVED
2011-07-27	SYS1-DBNDD2	SYS1-DBNDD2 readthrough	SYS1-DBNDD2	SYS1-DBNDD2 readthrough transcript	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message