Mir707 (microRNA 707) - Rat Genome Database

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Gene: Mir707 (microRNA 707) Mus musculus
Analyze
Symbol: Mir707
Name: microRNA 707
RGD ID: 1625879
MGI Page MGI
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: Mirn; Mirn707; mmu-mir-7; mmu-mir-707
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,499,123 - 44,499,195 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,499,123 - 44,499,195 (+)EnsemblGRCm39 Ensembl
GRCm38744,849,699 - 44,849,771 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl744,849,699 - 44,849,771 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,105,069 - 52,105,141 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera740,299,892 - 40,299,964 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


PMID:16381832   PMID:16582102   PMID:21267068   PMID:21822254  



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Variants in Mir707
1 total Variants

1 to 10 of 101 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 11q22.1-25(chr11:100348599-135040246)x3 copy number gain See cases [RCV000053638] Chr11:100348599..135040246 [GRCh38]
Chr11:100219331..134910140 [GRCh37]
Chr11:99724541..134415350 [NCBI36]
Chr11:11q22.1-25		 pathogenic
NM_152434.2(CWF19L2):c.1434-600A>C single nucleotide variant Lung cancer [RCV000109577] Chr11:107418887 [GRCh38]
Chr11:107289613 [GRCh37]
Chr11:11q22.3		 uncertain significance
GRCh38/hg38 11q14.3-22.3(chr11:91086659-109595582)x1 copy number loss See cases [RCV000138038] Chr11:91086659..109595582 [GRCh38]
Chr11:90819827..109466308 [GRCh37]
Chr11:90459475..108971518 [NCBI36]
Chr11:11q14.3-22.3		 pathogenic
GRCh37/hg19 11q22.3(chr11:106959465-107537265)x1 copy number loss See cases [RCV000239992] Chr11:106959465..107537265 [GRCh37]
Chr11:11q22.3		 uncertain significance
GRCh37/hg19 11q14.2-22.3(chr11:88152458-109414650)x1 copy number loss See cases [RCV000510457] Chr11:88152458..109414650 [GRCh37]
Chr11:11q14.2-22.3		 pathogenic
GRCh37/hg19 11q22.3(chr11:106767102-107561488)x3 copy number gain See cases [RCV000511621] Chr11:106767102..107561488 [GRCh37]
Chr11:11q22.3		 uncertain significance
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11q22.3(chr11:107072930-107283027)x1 copy number loss See cases [RCV000511100] Chr11:107072930..107283027 [GRCh37]
Chr11:11q22.3		 uncertain significance
GRCh37/hg19 11q22.2-22.3(chr11:102578709-107230611)x1 copy number loss not provided [RCV000683366] Chr11:102578709..107230611 [GRCh37]
Chr11:11q22.2-22.3		 likely pathogenic
1 to 10 of 101 rows

Predicted Targets
Summary Value
Count of predictions:6481
Count of gene targets:3811
Count of transcripts:5652
Interacting mature miRNAs:mmu-miR-707
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 46 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72684761560851775Mouse
38501071Stsl6_mSalmonella typhimurium susceptibility locus 6 (mouse)73419942551149748Mouse
1357586Mdmsc3_mmodifier of muscularity 3 (mouse)Not determined73444786968448018Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
39128210Lwq19_mliver weight QTL 19 (mouse)73349772758148965Mouse
11252140Fdr1_mfat response to dietary restriction 1 (mouse)74114882075148965Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
25394571Skmw59_mskeletal muscle weight 59, TA (mouse)74422494344675382Mouse

1 to 10 of 46 rows
RH136015  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38744,849,716 - 44,849,908UniSTSGRCm38
GRCm382164,946,782 - 164,948,095UniSTSGRCm38
MGSCv372164,772,282 - 164,773,595UniSTSGRCm37
MGSCv37752,105,086 - 52,105,278UniSTSGRCm37
Celera2170,884,116 - 170,885,429UniSTS
Celera740,299,909 - 40,300,101UniSTS
Cytogenetic Map2H1-H2UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map7B2UniSTS
06.MMHAP38FLB3.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38744,848,197 - 44,848,364UniSTSGRCm38
MGSCv37752,103,567 - 52,103,734UniSTSGRCm37
Celera740,298,390 - 40,298,557UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map7B4UniSTS
Whitehead_YAC7 UniSTS






RefSeq Transcripts NR_030488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC158231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000102096
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl744,499,123 - 44,499,195 (+)Ensembl
GRCm38.p6 Ensembl744,849,699 - 44,849,771 (+)Ensembl
RefSeq Acc Id: NR_030488
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39744,499,123 - 44,499,195 (+)NCBI
GRCm38744,849,699 - 44,849,771 (+)ENTREZGENE
MGSCv37752,105,069 - 52,105,141 (+)RGD
Celera740,299,892 - 40,299,964 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RGD ID:8663907
Promoter ID:EPDNEW_M9984
Type:multiple initiation site
Name:Mir707_1
Description:Mus musculus microRNA 707 , microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38744,849,702 - 44,849,762EPDNEW


Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000076051 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000102096 ENTREZGENE
MGD MGI:3629685 ENTREZGENE
miRBase MI0004691 ENTREZGENE
NCBI Gene 735269 ENTREZGENE
PhenoGen Mir707 PhenoGen
RNAcentral URS000040ECB0 RNACentral
  URS0000759939 RNACentral