Svs4 (seminal vesicle secretory protein 4) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Svs4 (seminal vesicle secretory protein 4) Mus musculus
Analyze
No known orthologs.
Symbol: Svs4
Name: seminal vesicle secretory protein 4
RGD ID: 1623277
MGI Page MGI
Description: Predicted to enable identical protein binding activity. Predicted to be located in extracellular region. Predicted to be part of protein-containing complex. Predicted to be active in extracellular space.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: S; seminal vesicle protein 2; seminal vesicle protein 4; seminal vesicle secretory protein IV; Sv; Svp-2; Svp-4; Svp2; Svp4; SVS IV; SVS-IV
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392164,117,876 - 164,120,227 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2164,117,872 - 164,120,379 (-)EnsemblGRCm39 Ensembl
GRCm382164,275,956 - 164,278,307 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2164,275,952 - 164,278,459 (-)EnsemblGRCm38mm10GRCm38
MGSCv372164,101,692 - 164,104,043 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362163,967,395 - 163,969,748 (-)NCBIMGSCv36mm8
Celera2170,207,832 - 170,210,183 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1352323   PMID:1353738   PMID:2378752   PMID:2484712   PMID:3034900   PMID:3181757   PMID:6101098   PMID:8487016   PMID:8672132   PMID:10349636   PMID:11042159   PMID:11076861  
PMID:11217851   PMID:12466851   PMID:12477932   PMID:15950183   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21677750   PMID:21873635  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:106
Count of miRNA genes:97
Interacting mature miRNAs:103
Transcripts:ENSMUST00000017142
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301907Rends_mrenal disease susceptibility (mouse)Not determined2135699221169699361Mouse
1300688Nidd2k_mNidd2 on KK-A (mouse)Not determined2158078337178442452Mouse
1558867Gnf3_mgrowth and fatness 3 (mouse)Not determined2152699221169117924Mouse
1301783Bhr1_mbronchial hyperresponsiveness 1 (mouse)Not determined2142593476178442452Mouse
12790983Bwq12_mbody weight QTL 12 (mouse)2148238204181755017Mouse
11038701Ltpr2e_mLeishmania tropica response 2e (mouse)2150212221181755017Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
1301019Bmd6_mbone mineral density 6 (mouse)Not determined2151778297181755017Mouse
1558939Gnf1_mgrowth and fatness 1 (mouse)Not determined2143773445169117924Mouse
4142450Lmr16_mleishmaniasis resistance 16 (mouse)Not determined2150212221181755017Mouse
1301085Lrnx10_mlearning-contextual 10 (mouse)Not determined2150212221181755017Mouse
11353826Bdln10_mbody length 10 (mouse)2140441482174441482Mouse
1300867Lore2_mloss of righting induced by ethanol 2 (mouse)Not determined2144515861180896594Mouse
1558917Gct8_mgranulosa cell tumorigenesis 8 (mouse)Not determined2149236907181755017Mouse
1300806Aod4_mautoimmune ovarian dysgenesis 4 (mouse)Not determined2145228719179228841Mouse
12910800Pwgrq3_mpre-weaning growth rate QTL 3 (mouse)2160611165169794802Mouse
1558991Tailq4_mtail length QTL 4 (mouse)Not determined2162736926178442452Mouse
1301961Bts1_mbladder tumor susceptibility 1 (mouse)Not determined2132024159166024330Mouse
14747002Mancz3_mmandible centroid size 3 (mouse)2152329820181755017Mouse
1300751Bdt1_mbone density traits 1 (mouse)Not determined2149988902181755017Mouse
1300622Cfld1_mcystic fibrosis lung disease 1 (mouse)Not determined2155823920181755017Mouse
12910810Pwbwq2_mpre-weaning body weight QTL 2 (mouse)2160611165169794802Mouse
1302003Sluc17_msusceptibility to lung cancer 17 (mouse)Not determined2162433493181755017Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124441920168241920Mouse
10054066Bwq9_mbody weight QTL 9 (mouse)Not determined2135699221169699361Mouse
10043956Gnf5_mgrowth and fatness 5 (mouse)Not determined2135699221169699361Mouse
1302013Tbbmd3_mtotal body bone mineral density 3 (mouse)Not determined2145196949179197085Mouse
10412080Hylaq2_mHyperlocomotor activity related QTL 2 (mouse)Not determined2151640941164119146Mouse
1357435Epfq2_mepididymal fat pad weight QTL 2 (mouse)Not determined2162736926178442452Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
12801456Intmrm1_mintima/media ratio modifier 1 (mouse)2142428347176428450Mouse
1357537Lith12_mlithogenic gene 12 (mouse)Not determined2156196464181755017Mouse
12801461Intim1_mintima modifier 1 (mouse)2142428347176428450Mouse
11049566Lmr28e_mleishmaniasis resistance 28e (mouse)2133144911167145058Mouse
1301348Alcp5_malcohol preference locus 5 (mouse)Not determined2163486407181755017Mouse
11049567Lmr28f_mleishmaniasis resistance 28f (mouse)2133144911167145058Mouse
1357484Bsbob_mBSB obesity (mouse)Not determined2143773445165665019Mouse
4141703Chlq13_mcirculating hormone level QTL 13 (mouse)Not determined2135699221169699361Mouse
11341717Rvfs1_mRift Valley fever susceptibility 1 (mouse)2135432544173449616Mouse
1301865Hdlq19_mHDL QTL 19 (mouse)Not determined2145518775179518926Mouse
4142211Nilac3_mnicotine induced locomotor activity 3 (mouse)Not determined2148664893181755017Mouse
12910520Scgq3_mspontaneous crescentic glomerulonephritis QTL 3 (mouse)2151709273174389124Mouse
1300846Pbwg11_mpostnatal body weight growth 11 (mouse)Not determined2138966600172966729Mouse
1301677Alcp6_malcohol preference locus 6 (mouse)Not determined2163486407181755017Mouse

Markers in Region
D2Mit29  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382164,277,112 - 164,277,226UniSTSGRCm38
MGSCv372164,102,848 - 164,102,962UniSTSGRCm37
Celera2170,208,988 - 170,209,102UniSTS
Cytogenetic Map2H3UniSTS
cM Map294.0UniSTS
Whitehead Genetic280.9UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000017142   ⟹   ENSMUSP00000017142
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2164,117,872 - 164,120,379 (-)Ensembl
GRCm38.p6 Ensembl2164,275,952 - 164,278,459 (-)Ensembl
RefSeq Acc Id: NM_009300   ⟹   NP_033326
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392164,117,876 - 164,120,227 (-)NCBI
GRCm382164,275,956 - 164,278,307 (-)ENTREZGENE
MGSCv372164,101,692 - 164,104,043 (-)RGD
Celera2170,207,832 - 170,210,183 (-)RGD
cM Map2 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_033326 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA40158 (Get FASTA)   NCBI Sequence Viewer  
  AAI15605 (Get FASTA)   NCBI Sequence Viewer  
  AAI15606 (Get FASTA)   NCBI Sequence Viewer  
  BAB32080 (Get FASTA)   NCBI Sequence Viewer  
  EDL06373 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000017142
  ENSMUSP00000017142.3
GenBank Protein P18419 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_033326   ⟸   NM_009300
- Peptide Label: precursor
- UniProtKB: Q14BU4 (UniProtKB/Swiss-Prot),   A2A4C3 (UniProtKB/Swiss-Prot),   Q9D257 (UniProtKB/Swiss-Prot),   P18419 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000017142   ⟸   ENSMUST00000017142

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P18419-F1-model_v2 AlphaFold P18419 1-113 view protein structure

Promoters
RGD ID:6879620
Promoter ID:EPDNEW_M3261
Type:initiation region
Name:Svs4_1
Description:Mus musculus seminal vesicle secretory protein 4 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382164,278,303 - 164,278,363EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98450 AgrOrtholog
Ensembl Genes ENSMUSG00000016998 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000017142 ENTREZGENE
  ENSMUST00000017142.3 UniProtKB/Swiss-Prot
InterPro Svs4/5/6 UniProtKB/Swiss-Prot
KEGG Report mmu:20941 UniProtKB/Swiss-Prot
MGD MGI:98450 ENTREZGENE
NCBI Gene 20941 ENTREZGENE
PANTHER PTHR17498 UniProtKB/Swiss-Prot
  SEMINAL VESICLE SECRETORY PROTEIN 4 UniProtKB/Swiss-Prot
Pfam Svs_4_5_6 UniProtKB/Swiss-Prot
PhenoGen Svs4 PhenoGen
UniProt A2A4C3 ENTREZGENE
  P18419 ENTREZGENE
  Q14BU4 ENTREZGENE
  Q9D257 ENTREZGENE
  SVS4_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary A2A4C3 UniProtKB/Swiss-Prot
  Q14BU4 UniProtKB/Swiss-Prot
  Q9D257 UniProtKB/Swiss-Prot