Arl14epl (ADP-ribosylation factor-like 14 effector protein-like) - Rat Genome Database

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Gene: Arl14epl (ADP-ribosylation factor-like 14 effector protein-like) Mus musculus
Analyze
Symbol: Arl14epl
Name: ADP-ribosylation factor-like 14 effector protein-like
RGD ID: 1621950
MGI Page MGI
Description: Orthologous to human ARL14EPL (ADP ribosylation factor like GTPase 14 effector protein like).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ARL14 effector protein-like; Gm949; hypothetical protein LOC381142; uncharacterized protein LOC381142
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391847,054,879 - 47,067,289 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1847,054,882 - 47,067,299 (+)EnsemblGRCm39 Ensembl
GRCm381846,921,812 - 46,934,222 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1846,921,815 - 46,934,232 (+)EnsemblGRCm38mm10GRCm38
MGSCv371847,081,469 - 47,093,876 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361847,047,146 - 47,059,553 (+)NCBIMGSCv36mm8
Celera1848,283,260 - 48,295,645 (+)NCBICelera
Cytogenetic Map18CNCBI
cM Map1824.88NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:17967808   PMID:18799693   PMID:21677750  
PMID:28467908   PMID:37196079  


Genomics

Comparative Map Data
Arl14epl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391847,054,879 - 47,067,289 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1847,054,882 - 47,067,299 (+)EnsemblGRCm39 Ensembl
GRCm381846,921,812 - 46,934,222 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1846,921,815 - 46,934,232 (+)EnsemblGRCm38mm10GRCm38
MGSCv371847,081,469 - 47,093,876 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361847,047,146 - 47,059,553 (+)NCBIMGSCv36mm8
Celera1848,283,260 - 48,295,645 (+)NCBICelera
Cytogenetic Map18CNCBI
cM Map1824.88NCBI
ARL14EPL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385116,032,472 - 116,059,489 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5116,032,324 - 116,060,118 (+)EnsemblGRCh38hg38GRCh38
GRCh375115,368,169 - 115,395,186 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365115,415,062 - 115,422,543 (+)NCBINCBI36Build 36hg18NCBI36
Celera5111,335,555 - 111,343,040 (+)NCBICelera
Cytogenetic Map5q23.1NCBI
HuRef5110,567,891 - 110,575,559 (+)NCBIHuRef
CHM1_15114,819,930 - 114,827,594 (+)NCBICHM1_1
T2T-CHM13v2.05116,544,843 - 116,571,873 (+)NCBIT2T-CHM13v2.0
Arl14epl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81841,866,458 - 41,897,431 (+)NCBIGRCr8
mRatBN7.21839,679,877 - 39,711,929 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1839,679,884 - 39,710,862 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01840,962,109 - 40,991,355 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1840,962,146 - 40,991,354 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01840,606,288 - 40,634,108 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41841,188,104 - 41,194,400 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1837,931,521 - 37,962,414 (+)NCBICelera
Cytogenetic Map18q11NCBI
Arl14epl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540835,858,944 - 35,865,040 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540835,859,152 - 35,864,159 (+)NCBIChiLan1.0ChiLan1.0
ARL14EPL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24111,277,569 - 111,304,571 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15109,431,230 - 109,458,232 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05111,405,276 - 111,413,850 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15117,202,911 - 117,210,567 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5117,202,911 - 117,210,567 (+)Ensemblpanpan1.1panPan2
ARL14EPL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1115,776,462 - 5,784,409 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl115,776,453 - 5,783,587 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha115,927,097 - 5,937,136 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0115,768,327 - 5,778,369 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl115,768,327 - 5,775,453 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1115,717,221 - 5,727,062 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0115,794,691 - 5,804,731 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0116,046,631 - 6,056,444 (+)NCBIUU_Cfam_GSD_1.0
Arl14epl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213128,505,917 - 128,548,270 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367421,223,936 - 1,248,614 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367421,242,686 - 1,248,575 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARL14EPL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2120,193,776 - 120,216,509 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12120,194,923 - 120,226,999 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22125,102,492 - 125,122,389 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARL14EPL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12319,324,669 - 19,349,282 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2319,343,090 - 19,348,394 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603459,057,336 - 59,082,591 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arl14epl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247335,799,714 - 5,802,691 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247335,799,243 - 5,841,456 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arl14epl
373 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:589
Count of miRNA genes:381
Interacting mature miRNAs:435
Transcripts:ENSMUST00000097580
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558743Kcal1_mkilocalorie 1 (mouse)Not determined181901887453018992Mouse
1302163Bmd16_mbone mineral density 16 (mouse)Not determined182966791463668060Mouse
11532716Sluc41c_msusceptibility to lung cancer 41c (mouse)182261991456620127Mouse
11532715Sluc41b_msusceptibility to lung cancer 41b (mouse)182261991456620127Mouse
10412184Sstapa1_mSuseptibility to Staphylococus aureus infection 1 (mouse)Not determined184654154657590708Mouse
11532710Sluc41a_msusceptibility to lung cancer 41a (mouse)182261991456620127Mouse
25823171Hrsq10_mhost response to SARS QTL 10, D4% weight (mouse)182724111558827077Mouse
11532709Sluc41_msusceptibility to lung cancer 41 (mouse)182095369457590708Mouse
1301400Lmr13_mleishmaniasis resistance 13 (mouse)Not determined182810938062109518Mouse
25823174Hrsq11_mhost response to SARS QTL 11, log titer (mouse)182724111558827077Mouse
1301215Thcr_mT helper cell response (mouse)Not determined184513060468778777Mouse
1300638Im7_mimmunoregulatory 7 (mouse)Not determined181901887453018992Mouse
25823173Hrsq12_mhost response to SARS QTL 12, hemorrhage (mouse)182489588178339555Mouse
1300994Pvcan3_mprotection against vaginal candidiasis 3 (mouse)Not determined181619964050199776Mouse
1301570Sluc14_msusceptibility to lung cancer 14 (mouse)Not determined182261991456620127Mouse
13504732Cath6_mcarotid atherosclerosis 6 (mouse)181363712647637126Mouse
1357639Obsty4_mobesity 4 (mouse)Not determined183961991484638778Mouse
1558849W3q15_mweight 3 weeks QTL 15 (mouse)Not determined18504111961272643Mouse
12880412V125Dq12_mvitamin D active form serum level QTL 12 (mouse)183023306764233067Mouse
1301771Pcyts6_mplasmacytoma susceptibility 6 (mouse)Not determined183565863269658851Mouse
1301902Hrtfm4_mheart failure modifier 4 (mouse)Not determined184331112077311343Mouse
1300877Adip8_madiposity 8 (mouse)Not determined182261991456620127Mouse
4141857Mhysq5_mmale hybrid sterility QTL 5 (mouse)Not determined2813060462130739Mouse
1300685Scc5_mcolon tumor susceptibility 5 (mouse)Not determined183198848065988629Mouse
4142366Chlq10_mcirculating hormone level QTL 10 (mouse)Not determined183629102270291180Mouse
12050070Nabq2_mnasal bone morphology QTL 2 (mouse)183910367773103793Mouse
1301307Phospq1_mphospholipid QTL 1 (mouse)Not determined181813970452139859Mouse
12904745Carcdq2_mcardiac collagen deposition QTL 2 (mouse)184642328780423287Mouse
11039493Ltpr8d_mLeishmania tropica response 8d (mouse)184687490380875042Mouse
1357690Vtbt19_mvertebral trabecular bone trait 19 (mouse)Not determined183309104367091221Mouse
11039494Ltpr8b_mLeishmania tropica response 8b (mouse)184687490380875042Mouse
4142031Moen1_mmodifier of engrailed QTL 1 (mouse)Not determined182411556058115730Mouse
15039381Ltgq8_mliver triglyceride QTL 8 (mouse)183820656972206569Mouse
12904950Smmq3_msoleus muscle mass QTL 3 (mouse)182605687560056875Mouse
15039383Mvlq5_mmicrovesicular liver lesion QTL 5 (mouse)183820656972206569Mouse
25823167Hrsq5_mhost response to SARS QTL 5, D3% weight (mouse)182724111558827077Mouse
1357603Mom3_mmodifier of Min 3 (mouse)Not determined181403002367098962Mouse
13463476Hctq8_mhematocrit QTL 8 (mouse)182121758055217727Mouse
27226723Tibw9_mtibia width 9, proximal, 16 week (mouse)18320000060933072Mouse
15039384Liviq1_mliver inflammation QTL 1 (mouse)183820656972206569Mouse
15039386Mvlq4_mmacrovesicular liver lesion QTL 4 (mouse)183820656972206569Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000097580   ⟹   ENSMUSP00000095187
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1847,059,049 - 47,067,289 (+)Ensembl
GRCm38.p6 Ensembl1846,925,982 - 46,934,222 (+)Ensembl
Ensembl Acc Id: ENSMUST00000234910   ⟹   ENSMUSP00000157009
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1847,054,882 - 47,067,299 (+)Ensembl
GRCm38.p6 Ensembl1846,921,815 - 46,934,232 (+)Ensembl
RefSeq Acc Id: NM_001033446   ⟹   NP_001028618
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391847,054,882 - 47,067,289 (+)NCBI
GRCm381846,921,815 - 46,934,222 (+)NCBI
MGSCv371847,081,469 - 47,093,876 (+)RGD
Celera1848,283,260 - 48,295,645 (+)RGD
cM Map18 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006526066   ⟹   XP_006526129
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391847,054,879 - 47,065,804 (+)NCBI
GRCm381846,921,812 - 46,932,737 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001028618 (Get FASTA)   NCBI Sequence Viewer  
  XP_006526129 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI47442 (Get FASTA)   NCBI Sequence Viewer  
  AAI47473 (Get FASTA)   NCBI Sequence Viewer  
  BAE26654 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000095187.2
  ENSMUSP00000157009
  ENSMUSP00000157009.2
GenBank Protein Q3UKZ7 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001028618   ⟸   NM_001033446
- UniProtKB: Q3UKZ7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006526129   ⟸   XM_006526066
- Peptide Label: isoform X1
- UniProtKB: Q3UKZ7 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000095187   ⟸   ENSMUST00000097580
Ensembl Acc Id: ENSMUSP00000157009   ⟸   ENSMUST00000234910

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3UKZ7-F1-model_v2 AlphaFold Q3UKZ7 1-152 view protein structure

Promoters
RGD ID:13677762
Promoter ID:EPDNEW_M23029
Type:multiple initiation site
Name:Arl14epl_1
Description:Mus musculus ADP-ribosylation factor-like 14 effector protein-like, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381846,921,818 - 46,921,878EPDNEW
RGD ID:6829278
Promoter ID:MM_KWN:25231
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:NM_001033446
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361847,081,166 - 47,081,666 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2685795 AgrOrtholog
Ensembl Genes ENSMUSG00000073568 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000097580.2 UniProtKB/Swiss-Prot
  ENSMUST00000234910 ENTREZGENE
  ENSMUST00000234910.2 UniProtKB/Swiss-Prot
InterPro ARF7EP_C UniProtKB/Swiss-Prot
  ARL14_effector UniProtKB/Swiss-Prot
KEGG Report mmu:381142 UniProtKB/Swiss-Prot
MGD MGI:2685795 ENTREZGENE
NCBI Gene 381142 ENTREZGENE
PANTHER ADP RIBOSYLATION FACTOR LIKE GTPASE 14 EFFECTOR PROTEIN LIKE UniProtKB/Swiss-Prot
  ARL14 EFFECTOR PROTEIN-LIKE UniProtKB/Swiss-Prot
Pfam ARF7EP_C UniProtKB/Swiss-Prot
PhenoGen Arl14epl PhenoGen
UniProt A14EL_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-09-19 Arl14epl  ADP-ribosylation factor-like 14 effector protein-like  Gm949  predicted gene 949  Symbol and/or name change 5135510 APPROVED