Mymx (myomixer, myoblast fusion factor) - Rat Genome Database

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Gene: Mymx (myomixer, myoblast fusion factor) Mus musculus
Analyze
Symbol: Mymx
Name: myomixer, myoblast fusion factor
RGD ID: 1620251
MGI Page MGI
Description: Involved in myoblast fusion involved in skeletal muscle regeneration; plasma membrane fusion; and skeletal muscle organ development. Located in Golgi membrane; endoplasmic reticulum membrane; and plasma membrane. Is expressed in diaphragm; foregut; limb; skeletal musculature; and tail paraxial mesenchyme. Human ortholog(s) of this gene implicated in Carey-Fineman-Ziter syndrome. Orthologous to human MYMX (myomixer, myoblast fusion factor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EG653016; embryonic stem cell- and germ cell-specific protein; Esgp; Gm7325; m; microprotein inducer of fusion; minion; myomer; myomerger; predicted gene 7325; uncharacterized LOC101929726 homolog
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391745,911,887 - 45,913,122 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1745,911,897 - 45,913,028 (-)EnsemblGRCm39 Ensembl
GRCm381745,600,961 - 45,602,196 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1745,600,971 - 45,602,102 (-)EnsemblGRCm38mm10GRCm38
MGSCv371745,737,916 - 45,739,051 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361745,064,552 - 45,065,496 (-)NCBIMGSCv36mm8
MGSCv361744,621,222 - 44,622,166 (-)NCBIMGSCv36mm8
Cytogenetic Map17CNCBI
cM Map1722.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:12904583   PMID:14610273   PMID:16141072   PMID:16331322   PMID:17062627   PMID:17967808   PMID:18799693   PMID:21267068   PMID:21677750   PMID:21873635   PMID:28386024   PMID:28569745  
PMID:28569755   PMID:28637957   PMID:29581287   PMID:30197239   PMID:30389854   PMID:33479215   PMID:37174683   PMID:37468485   PMID:37723138  


Genomics

Comparative Map Data
Mymx
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391745,911,887 - 45,913,122 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1745,911,897 - 45,913,028 (-)EnsemblGRCm39 Ensembl
GRCm381745,600,961 - 45,602,196 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1745,600,971 - 45,602,102 (-)EnsemblGRCm38mm10GRCm38
MGSCv371745,737,916 - 45,739,051 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361745,064,552 - 45,065,496 (-)NCBIMGSCv36mm8
MGSCv361744,621,222 - 44,622,166 (-)NCBIMGSCv36mm8
Cytogenetic Map17CNCBI
cM Map1722.59NCBI
MYMX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38644,192,721 - 44,218,234 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl644,216,926 - 44,218,236 (+)EnsemblGRCh38hg38GRCh38
GRCh37644,184,663 - 44,185,971 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map6p21.1NCBI
HuRef643,906,811 - 43,908,115 (+)NCBIHuRef
CHM1_1644,188,410 - 44,189,713 (+)NCBICHM1_1
T2T-CHM13v2.0644,051,103 - 44,052,410 (+)NCBIT2T-CHM13v2.0
Mymx
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8922,894,524 - 22,895,701 (+)NCBIGRCr8
mRatBN7.2915,397,086 - 15,398,263 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl915,397,144 - 15,398,263 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx923,983,681 - 23,984,858 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0929,046,358 - 29,047,535 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0927,347,118 - 27,348,295 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0917,781,397 - 17,783,074 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl917,782,395 - 17,782,664 (+)EnsemblRnor6.0rn6Rnor6.0
Celera913,140,601 - 13,142,278 (+)NCBICelera
Cytogenetic Map9q12NCBI
MYMX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2558,719,590 - 58,722,520 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1654,589,673 - 54,592,605 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0643,812,606 - 43,814,252 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1645,096,551 - 45,097,878 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl645,097,114 - 45,097,368 (+)Ensemblpanpan1.1panPan2
MYMX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11212,626,482 - 12,630,058 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1212,651,891 - 12,655,481 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01213,108,904 - 13,112,493 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1213,111,742 - 13,111,996 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11212,634,365 - 12,637,954 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01212,722,315 - 12,725,907 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01212,816,043 - 12,819,633 (+)NCBIUU_Cfam_GSD_1.0
Mymx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494648,095,049 - 48,096,795 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647615,863,807 - 15,864,161 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647615,863,807 - 15,864,357 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC110261530
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl739,216,513 - 39,216,779 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1739,215,933 - 39,217,275 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MYMX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366604444,270,375 - 44,271,682 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mymx
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475415,637,322 - 15,637,883 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mymx
40 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:552
Count of miRNA genes:151
Interacting mature miRNAs:171
Transcripts:ENSMUST00000113529, ENSMUST00000169137, ENSMUST00000178858
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173311897454107028Mouse
1300885Mbis4_mMycobacterium bovis-induced systemic lupus erythematosus 4 (mouse)Not determined173517581770165926Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172781520961815209Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3098790348039703Mouse
4141478Hbnr7_mHeligmosomoides bakeri nematode resistance 7 (mouse)Not determined4305118551739122Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
10755514Amzn2_manatomical modifier of Zfp423 2 (mouse)173596629469966424Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3103350065033630Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
12904951Smmq2_msoleus muscle mass QTL 2 (mouse)173678974370789743Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse
4141319Hmtb8_mhemostasis and thrombosis rebleeding time 8 (mouse)Not determined4053444774534623Mouse
26884386Skwq13_mskull length QTL 13, 16 week (mouse)174371089153107028Mouse
15039324Nmrs48_mNAFLD-associated magnetic resonance shift 48 (mouse)174093918774939187Mouse
26884390Skwq9_mskull length QTL 9, 10 week (mouse)174371089167806995Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172862240662622654Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
10755525Lymph2_mlymphocyte differential 2 (mouse)173880562672805626Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
1300592Pcyts5_mplasmacytoma susceptibility 5 (mouse)Not determined173871288772712970Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172688497260885114Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
25394539Skmw85_mskeletal muscle weight 85, gastroc (mouse)174370766846831957Mouse
10755534Lymph4_mlymphocyte differential 4 (mouse)173880562672805626Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172640101252911704Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
12903997Cfq4_mconditioned fear QTL 4 (mouse)174501655249366402Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined173013255564132666Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000113529   ⟹   ENSMUSP00000109157
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1745,912,262 - 45,913,028 (-)Ensembl
GRCm38.p6 Ensembl1745,601,336 - 45,602,102 (-)Ensembl
Ensembl Acc Id: ENSMUST00000169137   ⟹   ENSMUSP00000126690
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1745,912,180 - 45,912,892 (-)Ensembl
GRCm38.p6 Ensembl1745,601,254 - 45,601,966 (-)Ensembl
Ensembl Acc Id: ENSMUST00000178858   ⟹   ENSMUSP00000137630
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1745,911,897 - 45,912,993 (-)Ensembl
GRCm38.p6 Ensembl1745,600,971 - 45,602,067 (-)Ensembl
Ensembl Acc Id: ENSMUST00000208801   ⟹   ENSMUSP00000146823
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1745,912,279 - 45,912,896 (-)Ensembl
GRCm38.p6 Ensembl1745,601,353 - 45,601,970 (-)Ensembl
RefSeq Acc Id: NM_001177468   ⟹   NP_001170939
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391745,911,893 - 45,912,993 (-)NCBI
GRCm381745,600,967 - 45,602,067 (-)NCBI
MGSCv371745,737,916 - 45,739,051 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001177469   ⟹   NP_001170940
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391745,911,893 - 45,913,028 (-)NCBI
GRCm381745,600,967 - 45,602,102 (-)NCBI
MGSCv371745,737,916 - 45,739,051 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001177470   ⟹   NP_001170941
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391745,911,893 - 45,912,841 (-)NCBI
GRCm381745,600,967 - 45,601,915 (-)NCBI
MGSCv371745,737,916 - 45,739,051 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006524789   ⟹   XP_006524852
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391745,911,887 - 45,913,122 (-)NCBI
GRCm381745,600,961 - 45,602,196 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006524790   ⟹   XP_006524853
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391745,911,887 - 45,912,890 (-)NCBI
GRCm381745,600,961 - 45,601,964 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001170940   ⟸   NM_001177469
- Peptide Label: isoform 1
- UniProtKB: E9PXI1 (UniProtKB/Swiss-Prot),   Q2Q5T5 (UniProtKB/TrEMBL),   A0A223PZC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001170939   ⟸   NM_001177468
- Peptide Label: isoform 1
- UniProtKB: E9PXI1 (UniProtKB/Swiss-Prot),   Q2Q5T5 (UniProtKB/TrEMBL),   A0A223PZC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001170941   ⟸   NM_001177470
- Peptide Label: isoform 2
- UniProtKB: Q2Q5T5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006524852   ⟸   XM_006524789
- Peptide Label: isoform X1
- UniProtKB: E9PXI1 (UniProtKB/Swiss-Prot),   Q2Q5T5 (UniProtKB/TrEMBL),   A0A223PZC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006524853   ⟸   XM_006524790
- Peptide Label: isoform X1
- UniProtKB: E9PXI1 (UniProtKB/Swiss-Prot),   Q2Q5T5 (UniProtKB/TrEMBL),   A0A223PZC0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000137630   ⟸   ENSMUST00000178858
Ensembl Acc Id: ENSMUSP00000109157   ⟸   ENSMUST00000113529
Ensembl Acc Id: ENSMUSP00000146823   ⟸   ENSMUST00000208801
Ensembl Acc Id: ENSMUSP00000126690   ⟸   ENSMUST00000169137

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q2Q5T5-F1-model_v2 AlphaFold Q2Q5T5 1-84 view protein structure

Promoters
RGD ID:13676174
Promoter ID:EPDNEW_M22236
Type:initiation region
Name:Mymx_1
Description:Mus musculus myomixer, myoblast fusion factor , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M22237  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381745,601,903 - 45,601,963EPDNEW
RGD ID:13676176
Promoter ID:EPDNEW_M22237
Type:initiation region
Name:Mymx_2
Description:Mus musculus myomixer, myoblast fusion factor , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M22236  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381745,602,051 - 45,602,111EPDNEW
RGD ID:6828171
Promoter ID:MM_KWN:23589
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Kidney
Transcripts:DQ190000_GM7325,   ENSMUST00000113529
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361745,738,499 - 45,738,999 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3649059 AgrOrtholog
Ensembl Genes ENSMUSG00000079471 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000113529 ENTREZGENE
  ENSMUST00000113529.4 UniProtKB/Swiss-Prot
  ENSMUST00000169137 ENTREZGENE
  ENSMUST00000169137.3 UniProtKB/Swiss-Prot
  ENSMUST00000178858 ENTREZGENE
  ENSMUST00000178858.3 UniProtKB/Swiss-Prot
  ENSMUST00000208801 ENTREZGENE
  ENSMUST00000208801.2 UniProtKB/Swiss-Prot
InterPro Myomixer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:653016 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:3649059 ENTREZGENE
NCBI Gene 653016 ENTREZGENE
PANTHER PROTEIN MYOMIXER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR41686 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MINION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mymx PhenoGen
UniProt A0A223PZC0 ENTREZGENE, UniProtKB/TrEMBL
  E9PXI1 ENTREZGENE
  MYMX_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary E9PXI1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-30 Mymx  myomixer, myoblast fusion factor  Gm7325  predicted gene 7325  Symbol and/or name change 5135510 APPROVED