Cldn34b2 (claudin 34B2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Cldn34b2 (claudin 34B2) Mus musculus
Analyze
No known orthologs.
Symbol: Cldn34b2
Name: claudin 34B2
RGD ID: 1619967
MGI Page MGI
Description: Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be active in bicellular tight junction and plasma membrane. Orthologous to human CLDN34 (claudin 34).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1700042B14Rik; hypothetical protein LOC73347; MGC117726; RP23-440J5.4; uncharacterized protein LOC73347
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X153,907,913 - 153,930,845 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX153,907,913 - 153,911,408 (-)EnsemblGRCm39 Ensembl
GRCm38X155,124,917 - 155,147,849 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX155,124,917 - 155,128,412 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X151,559,524 - 151,582,392 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X150,465,633 - 150,488,565 (-)NCBIMGSCv36mm8
CeleraX138,433,014 - 138,455,868 (-)NCBICelera
Cytogenetic MapXF3NCBI
cM MapX72.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21677750   PMID:21873635   PMID:30973865   PMID:38355793  


Genomics

Variants

.
Variants in Cldn34b2
588 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:58
Count of miRNA genes:58
Interacting mature miRNAs:58
Transcripts:ENSMUST00000076671
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401118Pgia39_mproteoglycan induced arthritis 39 (mouse)Not determinedX144474380169476592Mouse
1558900Bw3_mbody weight QTL 3 (mouse)Not determinedX133540040165298595Mouse
1302000Pgia25_mproteoglycan induced arthritis 2 (mouse)Not determinedX144474380169476592Mouse
12738421Lfibq17_mliver fibrosis QTL 17 (mouse)X148148453164945064Mouse
1301209Cia19_mcollagen induced arthritis 19 (mouse)Not determinedX120993165160213038Mouse
10412164Cmv2_mcytomegalovirus resistance 2 (mouse)Not determinedX125685149159685269Mouse
1357823Spha3_msperm head anomaly 3 (mouse)Not determinedX102055848162758941Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000076671   ⟹   ENSMUSP00000075967
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX153,907,913 - 153,911,408 (-)Ensembl
GRCm38.p6 EnsemblX155,124,917 - 155,128,412 (-)Ensembl
RefSeq Acc Id: NM_001081671   ⟹   NP_001075140
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X153,907,913 - 153,930,845 (-)NCBI
GRCm38X155,124,917 - 155,147,849 (-)NCBI
MGSCv37X151,559,524 - 151,582,392 (-)RGD
CeleraX138,433,014 - 138,455,868 (-)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NM_028511   ⟹   NP_082787
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X153,907,913 - 153,911,408 (-)NCBI
GRCm38X155,124,917 - 155,128,412 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011247872   ⟹   XP_011246174
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X153,907,991 - 153,910,169 (-)NCBI
GRCm38X155,124,995 - 155,127,173 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001075140 (Get FASTA)   NCBI Sequence Viewer  
  NP_082787 (Get FASTA)   NCBI Sequence Viewer  
  XP_011246174 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI00354 (Get FASTA)   NCBI Sequence Viewer  
  BAB24701 (Get FASTA)   NCBI Sequence Viewer  
  EDL40851 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000075967
  ENSMUSP00000075967.4
RefSeq Acc Id: NP_001075140   ⟸   NM_001081671
- Peptide Label: precursor
- UniProtKB: Q9D9N2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011246174   ⟸   XM_011247872
- Peptide Label: isoform X1
- UniProtKB: Q9D9N2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_082787   ⟸   NM_028511
- Peptide Label: precursor
- UniProtKB: Q9D9N2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000075967   ⟸   ENSMUST00000076671

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D9N2-F1-model_v2 AlphaFold Q9D9N2 1-209 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1920597 AgrOrtholog
Ensembl Genes ENSMUSG00000057402 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000076671 ENTREZGENE
  ENSMUST00000076671.4 UniProtKB/TrEMBL
Gene3D-CATH 1.20.140.150 UniProtKB/TrEMBL
InterPro Claudin UniProtKB/TrEMBL
  PMP22/EMP/MP20/Claudin UniProtKB/TrEMBL
KEGG Report mmu:73347 UniProtKB/TrEMBL
MGD MGI:1920597 ENTREZGENE
NCBI Gene 73347 ENTREZGENE
PANTHER Claudin UniProtKB/TrEMBL
  CLAUDIN 34B1-RELATED UniProtKB/TrEMBL
Pfam Claudin_2 UniProtKB/TrEMBL
PhenoGen Cldn34b2 PhenoGen
UniProt Q9D9N2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-05-26 Cldn34b2  claudin 34B2  1700042B14Rik  RIKEN cDNA 1700042B14 gene  Symbol and/or name change 5135510 APPROVED