Zfy2 (zinc finger protein 2, Y-linked) - Rat Genome Database

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Gene: Zfy2 (zinc finger protein 2, Y-linked) Mus musculus
Analyze
No known orthologs.
Symbol: Zfy2
Name: zinc finger protein 2, Y-linked
RGD ID: 1619231
MGI Page MGI
Description: Predicted to enable DNA binding activity and metal ion binding activity. Acts upstream of or within dosage compensation by inactivation of X chromosome; meiotic recombination checkpoint signaling; and spermatid development. Predicted to be located in nucleus. Is expressed in heart; liver; lung; metanephros; and reproductive system.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Y-linked zinc finger protein 2; Zfy-2; zinc finger protein 2, Y linked; zinc finger Y-chromosomal protein 2
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Pseudogenes: Zfy2-ps1  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39Y2,106,175 - 2,170,409 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblY2,106,015 - 2,170,409 (-)EnsemblGRCm39 Ensembl
GRCm38Y2,106,175 - 2,170,409 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblY2,106,015 - 2,170,409 (-)EnsemblGRCm38mm10GRCm38
MGSCv37Y1,362,123 - 1,426,357 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36Y1,391,084 - 1,455,278 (-)NCBIMGSCv36mm8
CeleraY4,746,971 - 4,811,065 (-)NCBICelera
Cytogenetic MapYpterNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1449792   PMID:1691708   PMID:1698142   PMID:1774064   PMID:1797234   PMID:1968414   PMID:1970799   PMID:2105457   PMID:2265557   PMID:2480529   PMID:2493989   PMID:2514683  
PMID:2563173   PMID:2563174   PMID:2721933   PMID:6542174   PMID:6543304   PMID:7479793   PMID:7544442   PMID:7698773   PMID:7896271   PMID:8050362   PMID:8205722   PMID:8430091  
PMID:8678984   PMID:9096111   PMID:9126493   PMID:9598304   PMID:9755213   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12023983   PMID:12466851   PMID:12716983  
PMID:15618518   PMID:15975555   PMID:16141072   PMID:16141073   PMID:18287559   PMID:20059953   PMID:21530259   PMID:21873635   PMID:22407129   PMID:24496622   PMID:24967676   PMID:26719889  
PMID:26765744   PMID:27742779   PMID:28114340   PMID:28949961   PMID:35293998  


Genomics

Variants

.
Variants in Zfy2
55 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:66
Count of miRNA genes:65
Interacting mature miRNAs:66
Transcripts:ENSMUST00000115891
Prediction methods:Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
Zfy1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38Y726,092 - 726,402UniSTSGRCm38
GRCm38Y2,106,979 - 2,107,271UniSTSGRCm38
MGSCv37Y62,535 - 62,845UniSTSGRCm37
MGSCv37Y1,362,927 - 1,363,219UniSTSGRCm37
CeleraY4,747,775 - 4,748,067UniSTS
CeleraY3,571,980 - 3,572,290UniSTS
Cytogenetic MapYA1UniSTS
cM MapY2.01UniSTS
cM MapY2.2UniSTS
cM MapY2.2UniSTS
PMC136376P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38Y729,455 - 729,638UniSTSGRCm38
GRCm38Y2,109,730 - 2,109,913UniSTSGRCm38
MGSCv37Y65,898 - 66,081UniSTSGRCm37
MGSCv37Y1,365,678 - 1,365,861UniSTSGRCm37
CeleraY4,750,526 - 4,750,709UniSTS
CeleraY3,575,337 - 3,575,520UniSTS
Cytogenetic MapYA1UniSTS
Zfy2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38Y2,107,073 - 2,107,256UniSTSGRCm38
GRCm38Y726,186 - 726,387UniSTSGRCm38
MGSCv37Y62,629 - 62,830UniSTSGRCm37
MGSCv37Y1,363,021 - 1,363,204UniSTSGRCm37
CeleraY4,747,869 - 4,748,052UniSTS
CeleraY3,572,074 - 3,572,275UniSTS
Cytogenetic MapYA1UniSTS
cM MapY2.2UniSTS
PMC262401P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38Y725,993 - 726,403UniSTSGRCm38
GRCm38Y2,106,880 - 2,107,272UniSTSGRCm38
MGSCv37Y62,436 - 62,846UniSTSGRCm37
MGSCv37Y1,362,828 - 1,363,220UniSTSGRCm37
CeleraY4,747,676 - 4,748,068UniSTS
CeleraY3,571,881 - 3,572,291UniSTS
Cytogenetic MapYA1UniSTS
Zfy1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38Y726,566 - 726,779UniSTSGRCm38
GRCm38Y2,107,435 - 2,107,649UniSTSGRCm38
MGSCv37Y63,009 - 63,222UniSTSGRCm37
MGSCv37Y1,363,383 - 1,363,597UniSTSGRCm37
CeleraY3,572,454 - 3,572,667UniSTS
CeleraY4,748,231 - 4,748,445UniSTS
Cytogenetic MapYA1UniSTS
cM MapY2.01UniSTS
Zfy1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapYA1UniSTS
cM MapY2.2UniSTS
cM MapY2.01UniSTS
Zfy1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapYA1UniSTS
cM MapY2.01UniSTS
Zfy1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38Y725,811 - 726,428UniSTSGRCm38
GRCm38Y2,106,698 - 2,107,297UniSTSGRCm38
MGSCv37Y62,254 - 62,871UniSTSGRCm37
MGSCv37Y1,362,646 - 1,363,245UniSTSGRCm37
CeleraY3,571,515 - 3,572,316UniSTS
CeleraY4,747,494 - 4,748,093UniSTS
Cytogenetic MapYA1UniSTS
cM MapY2.2UniSTS
cM MapY2.01UniSTS
Zfy1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38Y725,811 - 726,428UniSTSGRCm38
GRCm38Y2,106,698 - 2,107,297UniSTSGRCm38
MGSCv37Y1,362,646 - 1,363,245UniSTSGRCm37
MGSCv37Y62,254 - 62,871UniSTSGRCm37
CeleraY4,747,494 - 4,748,093UniSTS
CeleraY3,571,515 - 3,572,316UniSTS
Cytogenetic MapYA1UniSTS
Zfy2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapYA1UniSTS
Zfy1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapYA1UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017318690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC161751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC163622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF074549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH003072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK133222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY159981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY159982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY159983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY159984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY159985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY159986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY159987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY159988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY159989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY159990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JN631149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JN631150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JN631151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JN631152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M24401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000115891   ⟹   ENSMUSP00000111557
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblY2,106,175 - 2,170,409 (-)Ensembl
GRCm38.p6 EnsemblY2,106,175 - 2,170,409 (-)Ensembl
Ensembl Acc Id: ENSMUST00000187148   ⟹   ENSMUSP00000139591
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblY2,106,015 - 2,150,346 (-)Ensembl
GRCm38.p6 EnsemblY2,106,015 - 2,150,346 (-)Ensembl
RefSeq Acc Id: NM_009571   ⟹   NP_033597
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39Y2,106,175 - 2,170,409 (-)NCBI
GRCm38Y2,106,175 - 2,170,409 (-)NCBI
MGSCv37Y1,362,123 - 1,426,357 (-)RGD
CeleraY4,746,971 - 4,811,065 (-)RGD
cM MapY ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017318690   ⟹   XP_017174179
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39Y2,106,176 - 2,121,823 (-)NCBI
GRCm38Y2,106,176 - 2,121,823 (-)NCBI
Sequence:
RefSeq Acc Id: NP_033597   ⟸   NM_009571
- UniProtKB: Q3V0D8 (UniProtKB/Swiss-Prot),   P20662 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017174179   ⟸   XM_017318690
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000111557   ⟸   ENSMUST00000115891
Ensembl Acc Id: ENSMUSP00000139591   ⟸   ENSMUST00000187148
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P20662-F1-model_v2 AlphaFold P20662 1-777 view protein structure

Promoters
RGD ID:13681906
Promoter ID:EPDNEW_M25102
Type:single initiation site
Name:Zfy2_1
Description:Mus musculus zinc finger protein 2, Y-linked , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38Y2,170,395 - 2,170,455EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99213 AgrOrtholog
Ensembl Genes ENSMUSG00000000103 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000115891 ENTREZGENE
  ENSMUST00000115891.2 UniProtKB/Swiss-Prot
  ENSMUST00000187148.7 UniProtKB/Swiss-Prot
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Snail/Krueppel_Znf UniProtKB/TrEMBL
  Transcrp_activ_Zfx/Zfy-dom UniProtKB/Swiss-Prot
  Zinc_finger/UBP_domain UniProtKB/Swiss-Prot
  Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:22768 UniProtKB/Swiss-Prot
MGD MGI:99213 ENTREZGENE
NCBI Gene 22768 ENTREZGENE
PANTHER CHROMATIN-LINKED ADAPTOR FOR MSL PROTEINS, ISOFORM B UniProtKB/TrEMBL
  PROTEIN ESCARGOT UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/Swiss-Prot
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 521 UniProtKB/Swiss-Prot
  ZINC FINGER Y-CHROMOSOMAL PROTEIN 1-LIKE ISOFORM X1 UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Zfx_Zfy_act UniProtKB/Swiss-Prot
PhenoGen Zfy2 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt H6U8U0_MOUSE UniProtKB/TrEMBL
  H6U8U1_MOUSE UniProtKB/TrEMBL
  H6U8U3_MOUSE UniProtKB/TrEMBL
  H6U8U4_MOUSE UniProtKB/TrEMBL
  H6U8U5_MOUSE UniProtKB/TrEMBL
  P20662 ENTREZGENE
  Q3V0D8 ENTREZGENE
  ZFY2_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q3V0D8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-10-20 Zfy2  zinc finger protein 2, Y-linked    zinc finger protein 2, Y linked  Symbol and/or name change 5135510 APPROVED