Meioc (meiosis specific with coiled-coil domain) - Rat Genome Database

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Gene: Meioc (meiosis specific with coiled-coil domain) Mus musculus
Analyze
Symbol: Meioc
Name: meiosis specific with coiled-coil domain
RGD ID: 1618845
MGI Page MGI
Description: Involved in several processes, including germ cell development; germline cell cycle switching, mitotic to meiotic cell cycle; and meiosis I. Located in cytoplasm and nucleus. Is expressed in several structures, including gut; liver; lung; reproductive system; and spleen. Orthologous to human MEIOC (meiosis specific with coiled-coil domain).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: gene model 1564, (NCBI); Gm1564; Gm663; hypothetical protein LOC268491; meiosis-specific coiled-coil domain-containing protein MEIOC; RP23-57F11.6; uncharacterized protein C17orf104 homolog; uncharacterized protein LOC268491
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911102,556,177 - 102,573,066 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11102,554,542 - 102,573,063 (+)EnsemblGRCm39 Ensembl
GRCm3811102,665,351 - 102,682,240 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11102,663,716 - 102,682,237 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711102,526,902 - 102,543,551 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611102,481,468 - 102,492,970 (+)NCBIMGSCv36mm8
Celera11114,376,159 - 114,392,710 (+)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1166.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IDA)
nucleus  (IBA,IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21677750   PMID:21873635   PMID:26742488  
PMID:28378742   PMID:28380054   PMID:29033321   PMID:29087293   PMID:30850578   PMID:31146259   PMID:34117224   PMID:35305312   PMID:36001654   PMID:38226173   PMID:38884383  


Genomics

Comparative Map Data
Meioc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911102,556,177 - 102,573,066 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11102,554,542 - 102,573,063 (+)EnsemblGRCm39 Ensembl
GRCm3811102,665,351 - 102,682,240 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11102,663,716 - 102,682,237 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711102,526,902 - 102,543,551 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611102,481,468 - 102,492,970 (+)NCBIMGSCv36mm8
Celera11114,376,159 - 114,392,710 (+)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1166.48NCBI
MEIOC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381744,656,468 - 44,677,087 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1744,656,404 - 44,690,308 (+)EnsemblGRCh38hg38GRCh38
GRCh371742,733,836 - 42,753,169 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361740,098,012 - 40,104,116 (+)NCBINCBI36Build 36hg18NCBI36
Celera1739,444,254 - 39,463,671 (+)NCBICelera
Cytogenetic Map17q21.31NCBI
HuRef1738,498,702 - 38,518,017 (+)NCBIHuRef
CHM1_11742,969,887 - 42,989,306 (+)NCBICHM1_1
T2T-CHM13v2.01745,510,420 - 45,531,046 (+)NCBIT2T-CHM13v2.0
Meioc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81088,128,939 - 88,147,833 (+)NCBIGRCr8
mRatBN7.21087,628,807 - 87,646,485 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1087,628,875 - 87,646,752 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01090,622,954 - 90,641,883 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1090,622,992 - 90,642,151 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01090,412,844 - 90,431,272 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41091,779,703 - 91,796,911 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1086,335,489 - 86,354,111 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
Meioc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545117,534,659 - 17,545,584 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545117,534,644 - 17,547,095 (+)NCBIChiLan1.0ChiLan1.0
MEIOC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21920,233,140 - 20,259,075 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11722,204,327 - 22,226,347 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01712,725,114 - 12,744,974 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11712,900,285 - 12,920,505 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1712,901,882 - 12,920,285 (-)Ensemblpanpan1.1panPan2
MEIOC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1918,795,289 - 18,814,677 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl918,796,799 - 18,814,682 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha918,180,320 - 18,198,942 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0919,489,451 - 19,508,094 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl919,490,961 - 19,508,194 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1918,342,626 - 18,361,153 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0918,524,579 - 18,543,260 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0918,682,095 - 18,700,798 (-)NCBIUU_Cfam_GSD_1.0
Meioc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560218,121,742 - 18,141,574 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365411,053,184 - 1,071,350 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365411,064,702 - 1,066,742 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MEIOC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1218,651,511 - 18,671,987 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11218,652,582 - 18,663,227 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21218,922,052 - 18,942,863 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MEIOC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11661,728,877 - 61,747,896 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1661,730,370 - 61,747,767 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607732,491,129 - 32,509,036 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Meioc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624795529,913 - 550,012 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624795527,562 - 554,337 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Meioc
508 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:892
Count of miRNA genes:484
Interacting mature miRNAs:580
Transcripts:ENSMUST00000100378, ENSMUST00000155813, ENSMUST00000156590
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
1301012Vispl_mvisual placing (mouse)Not determined11101022590121973369Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196176465108806384Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
12910539Sstapa3_msuseptibility to Staphylococcus aureus infection 3 (mouse)1196897693110603991Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185844911119844911Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179156009107616472Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181810267115810267Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177770978111771099Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94437183118022724Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1192939373112544554Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
1357631Motr1_mmodifier of tubby retinal degeneration 1 (mouse)Not determined1187691198103274115Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
11341721Rvfs2_mRift Valley fever susceptibility 2 (mouse)11100254186120887165Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181574481115574636Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187490826121873369Mouse
14746970Manh71_mmandible shape 71 (mouse)1179416257113416257Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179813759104502698Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198352609121973369Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194063779118022724Mouse
1300957Pbd1_mpeak bone density 1 (mouse)Not determined11102344123112384123Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198500469121973369Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196810136121973369Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195403965121973369Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193229183121973369Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194190826118890826Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
14700693Ppiq12_mprepulse inhibition QTL 12 (mouse)11101504820114472363Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186608320120608320Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191604608121973369Mouse
14700694Ppiq13_mprepulse inhibition QTL 13 (mouse)11101504820114472363Mouse
14700695Ppiq14_mprepulse inhibition QTL 14 (mouse)11101504820114472363Mouse
10044001Alcw8_malcohol withdrawal 8 (mouse)Not determined1199254187121973369Mouse
14700696Ppiq15_mprepulse inhibition QTL 15 (mouse)11101504820114472363Mouse
11553867Stmm5_mskin tumor modifier of MSM 5 (mouse)11100058103121973369Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187502600121502698Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000100378   ⟹   ENSMUSP00000097947
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11102,556,414 - 102,573,063 (+)Ensembl
GRCm38.p6 Ensembl11102,665,588 - 102,682,237 (+)Ensembl
Ensembl Acc Id: ENSMUST00000155813
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11102,556,449 - 102,564,950 (+)Ensembl
GRCm38.p6 Ensembl11102,665,623 - 102,674,124 (+)Ensembl
Ensembl Acc Id: ENSMUST00000156590   ⟹   ENSMUSP00000116246
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11102,554,542 - 102,566,134 (+)Ensembl
GRCm38.p6 Ensembl11102,663,716 - 102,675,308 (+)Ensembl
RefSeq Acc Id: NM_001127576   ⟹   NP_001121048
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911102,556,411 - 102,573,064 (+)NCBI
GRCm3811102,665,585 - 102,682,238 (+)NCBI
MGSCv3711102,526,902 - 102,543,551 (+)RGD
Celera11114,376,156 - 114,392,711 (+)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006533415   ⟹   XP_006533478
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911102,556,177 - 102,573,057 (+)NCBI
GRCm3811102,665,351 - 102,682,231 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006533416   ⟹   XP_006533479
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911102,556,179 - 102,573,066 (+)NCBI
GRCm3811102,665,353 - 102,682,240 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001121048 (Get FASTA)   NCBI Sequence Viewer  
  XP_006533478 (Get FASTA)   NCBI Sequence Viewer  
  XP_006533479 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein A2AG06 (Get FASTA)   NCBI Sequence Viewer  
  BAE20789 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000097947
  ENSMUSP00000097947.4
  ENSMUSP00000116246.2
RefSeq Acc Id: NP_001121048   ⟸   NM_001127576
- UniProtKB: Q3V2K8 (UniProtKB/Swiss-Prot),   A2AG06 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006533478   ⟸   XM_006533415
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006533479   ⟸   XM_006533416
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSMUSP00000097947   ⟸   ENSMUST00000100378
Ensembl Acc Id: ENSMUSP00000116246   ⟸   ENSMUST00000156590

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A2AG06-F1-model_v2 AlphaFold A2AG06 1-965 view protein structure

Promoters
RGD ID:8676916
Promoter ID:EPDNEW_M16488
Type:initiation region
Name:Meioc_1
Description:Mus musculus meiosis specific with coiled-coil domain , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811102,665,585 - 102,665,645EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2686410 AgrOrtholog
Ensembl Genes ENSMUSG00000051455 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000100378 ENTREZGENE
  ENSMUST00000100378.4 UniProtKB/Swiss-Prot
  ENSMUST00000156590.8 UniProtKB/TrEMBL
InterPro MEIOC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:268491 UniProtKB/Swiss-Prot
MGD MGI:2686410 ENTREZGENE
NCBI Gene Meioc ENTREZGENE
PANTHER MEIOSIS-SPECIFIC COILED-COIL DOMAIN-CONTAINING PROTEIN MEIOC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR33861 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MEIOC UniProtKB/Swiss-Prot
PhenoGen Meioc PhenoGen
PROSITE PHOSPHOPANTETHEINE UniProtKB/Swiss-Prot
UniProt A0A0R3P9D4_MOUSE UniProtKB/TrEMBL
  A2AG06 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3V2K8 ENTREZGENE
UniProt Secondary Q3V2K8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-21 Meioc  meiosis specific with coiled-coil domain  Gm1564  gene model 1564, (NCBI)  Symbol and/or name change 5135510 APPROVED
2024-08-21 Gm1564  gene model 1564, (NCBI)  Meioc  meiosis specific with coiled-coil domain  Symbol and/or name change 5135510 APPROVED
2015-11-17 Meioc  meiosis specific with coiled-coil domain  Gm1564  predicted gene 1564  Symbol and/or name change 5135510 APPROVED