Zglp1 (zinc finger, GATA-like protein 1) - Rat Genome Database

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Gene: Zglp1 (zinc finger, GATA-like protein 1) Mus musculus
Analyze
Symbol: Zglp1
Name: zinc finger, GATA-like protein 1
RGD ID: 1618444
MGI Page MGI
Description: Enables DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in oocyte development; regulation of transcription by RNA polymerase II; and spermatogenesis. Located in nucleus. Is expressed in several structures, including gonad; heart; liver; lung; and spleen. Orthologous to human ZGLP1 (zinc finger GATA like protein 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GATA-like 1; GATA-like protein 1; GATA-type zinc finger protein 1; Gl; GLP-1; Glp1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39920,973,689 - 20,978,389 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl920,973,689 - 20,978,389 (-)EnsemblGRCm39 Ensembl
GRCm38921,062,393 - 21,067,093 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl921,062,393 - 21,067,093 (-)EnsemblGRCm38mm10GRCm38
MGSCv37920,866,837 - 20,871,537 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36920,866,837 - 20,871,537 (-)NCBIMGSCv36mm8
Celera918,331,108 - 18,335,808 (-)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.7NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA,IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16982049   PMID:19915011   PMID:21123517   PMID:21873635   PMID:22384126   PMID:24356748   PMID:25201875   PMID:25976560   PMID:29056294   PMID:32054698   PMID:35401813  


Genomics

Comparative Map Data
Zglp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39920,973,689 - 20,978,389 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl920,973,689 - 20,978,389 (-)EnsemblGRCm39 Ensembl
GRCm38921,062,393 - 21,067,093 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl921,062,393 - 21,067,093 (-)EnsemblGRCm38mm10GRCm38
MGSCv37920,866,837 - 20,871,537 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36920,866,837 - 20,871,537 (-)NCBIMGSCv36mm8
Celera918,331,108 - 18,335,808 (-)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.7NCBI
ZGLP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381910,304,803 - 10,309,815 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1910,304,803 - 10,309,880 (-)EnsemblGRCh38hg38GRCh38
GRCh371910,415,479 - 10,420,491 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,276,479 - 10,281,233 (-)NCBINCBI36Build 36hg18NCBI36
Celera1910,310,872 - 10,315,626 (-)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef199,995,741 - 10,000,495 (-)NCBIHuRef
CHM1_11910,416,037 - 10,420,791 (-)NCBICHM1_1
T2T-CHM13v2.01910,430,915 - 10,435,928 (-)NCBIT2T-CHM13v2.0
Zglp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8827,876,046 - 27,880,953 (-)NCBIGRCr8
mRatBN7.2819,599,871 - 19,604,762 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl819,599,998 - 19,604,547 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0822,081,439 - 22,086,446 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl822,081,700 - 22,086,095 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0822,138,172 - 22,143,133 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4820,086,590 - 20,091,165 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera820,994,242 - 20,999,249 (-)NCBICelera
Cytogenetic Map8q13NCBI
Zglp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554951,585,473 - 1,590,321 (-)NCBIChiLan1.0ChiLan1.0
ZGLP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22015,221,776 - 15,227,055 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11914,220,398 - 14,225,695 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0199,855,211 - 9,860,326 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11910,520,072 - 10,524,784 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1910,520,360 - 10,524,757 (-)Ensemblpanpan1.1panPan2
ZGLP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12050,802,878 - 50,805,665 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2050,803,432 - 50,805,346 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2050,672,631 - 50,675,419 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02051,324,506 - 51,327,300 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12050,530,653 - 50,533,431 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02050,959,417 - 50,962,197 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02051,200,542 - 51,203,324 (+)NCBIUU_Cfam_GSD_1.0
RAVER1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl269,121,300 - 69,124,299 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1 Ensembl269,129,765 - 69,143,042 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1 Ensembl269,124,765 - 69,129,537 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1269,121,300 - 69,129,643 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2269,459,113 - 69,464,011 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZGLP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.169,353,883 - 9,359,187 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl69,353,859 - 9,357,927 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607410,680,532 - 10,685,038 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zglp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248282,463,685 - 2,468,174 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248282,463,440 - 2,468,555 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Zglp1
110 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:177
Count of miRNA genes:164
Interacting mature miRNAs:172
Transcripts:ENSMUST00000115494
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
35673312Ari7_mantibody response to influenza 7, day 45, IgG3 (mouse)9780000122211296Mouse
4142326Tgq19_mtriglyceride QTL 19 (mouse)Not determined121060750Mouse
13504834Hdlq109_mHDL QTL 109 (mouse)91670964150709641Mouse
1357465Vtbt6_mvertebral trabecular bone trait 6 (mouse)Not determined91697884050978943Mouse
13504833Bglu19_mblood glucose level 19 (mouse)9991076843910768Mouse
1357637Si5lq2_mserum IGFBP-5 level QTL 2 (mouse)Not determined91541175149411890Mouse
12790993Adq1_maortic diameter QTL 1 (mouse)91574962749749627Mouse
10043917Obq37_mobesity QTL 37 (mouse)Not determined91339117547391175Mouse
12790997Adq2_maortic diameter QTL 2 (mouse)91574962749749627Mouse
12880415V125Dq7_mvitamin D active form serum level QTL 7 (mouse)91601129650011296Mouse
1300849Sles4_msystemic lupus erythmatosus suppressor 4 (mouse)Not determined9910756237306370Mouse
12880416V125Dq8_mvitamin D active form serum level QTL 8 (mouse)91601129650011296Mouse
13434920Dcollq1_mdifferential colonization level QTL 1 (mouse)9130341840Mouse
1301045Sluc10_msusceptibility to lung cancer 10 (mouse)Not determined92030619754306370Mouse
1300532Tbs2_mtuberculosis severity 2 (mouse)Not determined91236997046370114Mouse
4141591Cq4_mcholesterol QTL 4 (mouse)Not determined91541175149411890Mouse
1301883Skull12_mskull morphology 12 (mouse)Not determined92030619754306370Mouse
11354951Pdcc3_mplasmacytoid dentritic cell compartment 3 (mouse)91574962749749627Mouse
1301439Morph2_mmorphine antinociception 2 (mouse)Not determined92015336254153492Mouse
4142352Lmr17_mleishmaniasis resistance 17 (mouse)Not determined92030619754306370Mouse
12904939Edlmmq8_mextensor digitorum longus muscle mass QTL 8 (mouse)92085274054852740Mouse
1300899Chol6_mcholesterol 6 (mouse)Not determined9129902913Mouse
1300643Pvcan2_mprotection against vaginal candidiasis 2 (mouse)Not determined91994340653943525Mouse
10043950Pbft5_mpercent body fat 5 (mouse)Not determined92030619754306370Mouse
4141447Cfmq2_mcystic fibrosis modifier QTL 2 (mouse)Not determined91541175149411890Mouse
1301421Lgth4_mbody length 4 (mouse)Not determined91541175149411890Mouse

Markers in Region
UniSTS:236068  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38921,067,535 - 21,067,746UniSTSGRCm38
MGSCv37920,871,979 - 20,872,190UniSTSGRCm37
Celera918,336,250 - 18,336,461UniSTS
Cytogenetic Map9A3UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000115494   ⟹   ENSMUSP00000111157
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl920,973,689 - 20,978,389 (-)Ensembl
GRCm38.p6 Ensembl921,062,393 - 21,067,093 (-)Ensembl
Ensembl Acc Id: ENSMUST00000216967
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl920,973,691 - 20,974,091 (-)Ensembl
GRCm38.p6 Ensembl921,062,395 - 21,062,795 (-)Ensembl
RefSeq Acc Id: NM_001103168   ⟹   NP_001096638
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39920,973,689 - 20,978,389 (-)NCBI
GRCm38921,062,393 - 21,067,093 (-)ENTREZGENE
MGSCv37920,866,837 - 20,871,537 (-)RGD
Celera918,331,108 - 18,335,808 (-)RGD
cM Map9 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001096638 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABB89941 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000111157
  ENSMUSP00000111157.3
GenBank Protein Q1WG82 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001096638   ⟸   NM_001103168
- UniProtKB: Q1WG82 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000111157   ⟸   ENSMUST00000115494

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q1WG82-F1-model_v2 AlphaFold Q1WG82 1-266 view protein structure

Promoters
RGD ID:6844556
Promoter ID:MM_KWN:56544
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour
Transcripts:UC009VEU.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36920,871,566 - 20,872,687 (-)MPROMDB
RGD ID:6845376
Promoter ID:MM_KWN:56545
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000115494,   UC009OKB.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36920,877,681 - 20,878,917 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3696042 AgrOrtholog
Ensembl Genes ENSMUSG00000079681 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000115494 ENTREZGENE
  ENSMUST00000115494.3 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.50.10 UniProtKB/Swiss-Prot
InterPro GATA-type_ZnF_Regulator UniProtKB/Swiss-Prot
  Znf_GATA UniProtKB/Swiss-Prot
  Znf_NHR/GATA UniProtKB/Swiss-Prot
KEGG Report mmu:100009600 UniProtKB/Swiss-Prot
MGD MGI:3696042 ENTREZGENE
NCBI Gene 100009600 ENTREZGENE
PANTHER GATA-TYPE ZINC FINGER PROTEIN 1 UniProtKB/Swiss-Prot
  GATA-TYPE ZINC FINGER PROTEIN 1 UniProtKB/Swiss-Prot
Pfam GATA UniProtKB/Swiss-Prot
PhenoGen Zglp1 PhenoGen
PRINTS GATAZNFINGER UniProtKB/Swiss-Prot
PROSITE GATA_ZN_FINGER_2 UniProtKB/Swiss-Prot
SMART ZnF_GATA UniProtKB/Swiss-Prot
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot
UniProt Q1WG82 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-27 Zglp1  zinc finger, GATA-like protein 1  Glp1  GATA-like 1  Symbol and/or name change 5135510 APPROVED