Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-alpha-phellandrene | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of PCYOX1L mRNA | CTD | PMID:25075043 | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of PCYOX1L mRNA | CTD | PMID:22206623 | 1-naphthyl isothiocyanate | increases expression | ISO | Pcyox1l (Rattus norvegicus) | 6480464 | 1-Naphthylisothiocyanate results in increased expression of PCYOX1L mRNA | CTD | PMID:30723492 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in decreased methylation of PCYOX1L gene | CTD | PMID:21212295 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Pcyox1l (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PCYOX1L mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PCYOX1L mRNA | CTD | PMID:28922406 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PCYOX1L mRNA | CTD | PMID:20106945 and PMID:21632981 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PCYOX1L mRNA | CTD | PMID:21570461 | 2,4,6-tribromophenol | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of PCYOX1L protein | CTD | PMID:31675489 | 6-propyl-2-thiouracil | decreases expression | ISO | Pcyox1l (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of PCYOX1L mRNA | CTD | PMID:30047161 | acetamide | increases expression | ISO | Pcyox1l (Rattus norvegicus) | 6480464 | acetamide results in increased expression of PCYOX1L mRNA | CTD | PMID:31881176 | acrolein | multiple interactions | ISO | PCYOX1L (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PCYOX1L mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PCYOX1L mRNA | CTD | PMID:32699268 | acrylamide | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of PCYOX1L mRNA | CTD | PMID:32763439 | all-trans-retinoic acid | increases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Tretinoin results in increased expression of PCYOX1L mRNA | CTD | PMID:33167477 | alpha-phellandrene | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of PCYOX1L mRNA | CTD | PMID:25075043 | alpha-pinene | multiple interactions | ISO | PCYOX1L (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PCYOX1L mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PCYOX1L mRNA | CTD | PMID:32699268 | amitrole | decreases expression | ISO | Pcyox1l (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of PCYOX1L mRNA | CTD | PMID:30047161 | antirheumatic drug | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of PCYOX1L mRNA | CTD | PMID:24449571 | aristolochic acid A | increases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of PCYOX1L mRNA | CTD | PMID:33212167 | benzo[a]pyrene | increases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of PCYOX1L mRNA | CTD | PMID:26238291 | benzo[a]pyrene | affects methylation | ISO | PCYOX1L (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of PCYOX1L intron | CTD | PMID:30157460 | bisphenol A | affects expression | ISO | Pcyox1l (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of PCYOX1L mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | ISO | PCYOX1L (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of PCYOX1L gene | CTD | PMID:31601247 | bisphenol A | decreases methylation | ISO | PCYOX1L (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of PCYOX1L gene | CTD | PMID:31601247 | cadmium atom | increases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Cadmium results in increased expression of PCYOX1L mRNA | CTD | PMID:24376830 | cadmium atom | multiple interactions | ISO | PCYOX1L (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PCYOX1L mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | PCYOX1L (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PCYOX1L mRNA | CTD | PMID:35301059 | carbamazepine | affects expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Carbamazepine affects the expression of PCYOX1L mRNA | CTD | PMID:25979313 | cisplatin | increases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Cisplatin results in increased expression of PCYOX1L mRNA | CTD | PMID:27594783 | cisplatin | multiple interactions | ISO | PCYOX1L (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of PCYOX1L mRNA | CTD | PMID:27392435 | clobetasol | increases expression | EXP | | 6480464 | Clobetasol results in increased expression of PCYOX1L mRNA | CTD | PMID:27462272 | copper atom | increases expression | ISO | Pcyox1l (Rattus norvegicus) | 6480464 | Copper results in increased expression of PCYOX1L mRNA | CTD | PMID:30556269 | copper(0) | increases expression | ISO | Pcyox1l (Rattus norvegicus) | 6480464 | Copper results in increased expression of PCYOX1L mRNA | CTD | PMID:30556269 | cyclosporin A | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of PCYOX1L mRNA | CTD | PMID:20106945 | decabromodiphenyl ether | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of PCYOX1L protein | CTD | PMID:31675489 | deoxynivalenol | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | deoxynivalenol results in decreased expression of PCYOX1L mRNA | CTD | PMID:31863870 | doxorubicin | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PCYOX1L mRNA | CTD | PMID:29803840 | elemental selenium | multiple interactions | ISO | PCYOX1L (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of PCYOX1L mRNA | CTD | PMID:19244175 | elemental selenium | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Selenium results in decreased expression of PCYOX1L mRNA | CTD | PMID:19244175 | endosulfan | increases expression | ISO | Pcyox1l (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of PCYOX1L mRNA | CTD | PMID:29391264 | ethanol | affects expression | EXP | | 6480464 | Ethanol affects the expression of PCYOX1L mRNA | CTD | PMID:30319688 | fulvestrant | multiple interactions | ISO | PCYOX1L (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of PCYOX1L gene | CTD | PMID:31601247 | gentamycin | decreases expression | ISO | Pcyox1l (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of PCYOX1L mRNA | CTD | PMID:33387578 | ivermectin | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PCYOX1L protein | CTD | PMID:32959892 | lipopolysaccharide | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in decreased methylation of PCYOX1L gene | CTD | PMID:21212295 | menadione | affects expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of PCYOX1L mRNA | CTD | PMID:20044591 | methamphetamine | decreases expression | ISO | Pcyox1l (Rattus norvegicus) | 6480464 | Methamphetamine results in decreased expression of PCYOX1L mRNA | CTD | PMID:19564919 | miconazole | increases expression | EXP | | 6480464 | Miconazole results in increased expression of PCYOX1L mRNA | CTD | PMID:27462272 | ozone | multiple interactions | ISO | PCYOX1L (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PCYOX1L mRNA more ... | CTD | PMID:32699268 | perfluorohexanesulfonic acid | increases expression | EXP | | 6480464 | perfluorohexanesulfonic acid results in increased expression of PCYOX1L mRNA | CTD | PMID:37995155 | selenium atom | multiple interactions | ISO | PCYOX1L (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of PCYOX1L mRNA | CTD | PMID:19244175 | selenium atom | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Selenium results in decreased expression of PCYOX1L mRNA | CTD | PMID:19244175 | silicon dioxide | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of PCYOX1L mRNA | CTD | PMID:25895662 | sunitinib | increases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Sunitinib results in increased expression of PCYOX1L mRNA | CTD | PMID:31533062 | T-2 toxin | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | T-2 Toxin results in decreased expression of PCYOX1L mRNA | CTD | PMID:31863870 | tamoxifen | increases expression | EXP | | 6480464 | Tamoxifen results in increased expression of PCYOX1L mRNA | CTD | PMID:25123088 | tert-butyl hydroperoxide | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of PCYOX1L mRNA | CTD | PMID:15336504 | testosterone | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Testosterone results in decreased expression of PCYOX1L mRNA | CTD | PMID:33359661 | thioacetamide | increases expression | ISO | Pcyox1l (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of PCYOX1L mRNA | CTD | PMID:23411599 and PMID:34492290 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of PCYOX1L mRNA | CTD | PMID:23131501 and PMID:23409001 | trichostatin A | increases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | trichostatin A results in increased expression of PCYOX1L mRNA | CTD | PMID:24935251 | trichostatin A | affects expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | trichostatin A affects the expression of PCYOX1L mRNA | CTD | PMID:28542535 | trimellitic anhydride | increases expression | EXP | | 6480464 | trimellitic anhydride results in increased expression of PCYOX1L mRNA | CTD | PMID:19042947 | triptonide | affects expression | EXP | | 6480464 | triptonide affects the expression of PCYOX1L mRNA | CTD | PMID:33045310 | trovafloxacin | decreases expression | EXP | | 6480464 | trovafloxacin results in decreased expression of PCYOX1L mRNA | CTD | PMID:35537566 | valproic acid | increases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PCYOX1L mRNA | CTD | PMID:19101580 more ... | valproic acid | affects expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PCYOX1L mRNA | CTD | PMID:25979313 | vinclozolin | increases expression | ISO | Pcyox1l (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of PCYOX1L mRNA | CTD | PMID:22570695 | vinclozolin | decreases expression | ISO | Pcyox1l (Rattus norvegicus) | 6480464 | vinclozolin results in decreased expression of PCYOX1L mRNA | CTD | PMID:23034163 | vitamin E | multiple interactions | ISO | PCYOX1L (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of PCYOX1L mRNA | CTD | PMID:19244175 | vitamin E | decreases expression | ISO | PCYOX1L (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of PCYOX1L mRNA | CTD | PMID:19244175 | |