PMS2P3 (PMS1 homolog 2, mismatch repair system component pseudogene 3) - Rat Genome Database

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Gene: PMS2P3 (PMS1 homolog 2, mismatch repair system component pseudogene 3) Homo sapiens
Analyze
Symbol: PMS2P3
Name: PMS1 homolog 2, mismatch repair system component pseudogene 3
RGD ID: 1606835
HGNC Page HGNC:9128
Description: Predicted to enable ATP hydrolysis activity and ATP-dependent DNA damage sensor activity. Predicted to be involved in mismatch repair and regulation of DNA-templated transcription. Predicted to be part of mismatch repair complex.
Type: pseudo (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Previously known as: MGC126647; PMS2L3; PMS2L9; PMS5; PMSR3
RGD Orthologs
Mouse
Alliance Orthologs
More Info more info ...
Related Functional Gene: PMS2  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38775,507,747 - 75,528,123 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl775,510,931 - 75,516,235 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl775,490,413 - 75,528,172 (-)EnsemblGRCh38hg38GRCh38
GRCh37775,137,069 - 75,157,453 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36774,975,005 - 74,995,330 (-)NCBINCBI36Build 36hg18NCBI36
Celera770,004,871 - 70,025,253 (-)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef770,239,269 - 70,243,167 (-)NCBIHuRef
HuRef762,940,232 - 62,947,271 (-)NCBIHuRef
CHM1_1775,067,163 - 75,087,539 (-)NCBICHM1_1
T2T-CHM13v2.0776,795,078 - 76,815,462 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2774,470,133 - 74,490,517 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7980603   PMID:8586419   PMID:10737800   PMID:12477932   PMID:20819778   PMID:21873635   PMID:33961781  


Genomics

Comparative Map Data
PMS2P3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38775,507,747 - 75,528,123 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl775,510,931 - 75,516,235 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl775,490,413 - 75,528,172 (-)EnsemblGRCh38hg38GRCh38
GRCh37775,137,069 - 75,157,453 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36774,975,005 - 74,995,330 (-)NCBINCBI36Build 36hg18NCBI36
Celera770,004,871 - 70,025,253 (-)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef770,239,269 - 70,243,167 (-)NCBIHuRef
HuRef762,940,232 - 62,947,271 (-)NCBIHuRef
CHM1_1775,067,163 - 75,087,539 (-)NCBICHM1_1
T2T-CHM13v2.0776,795,078 - 76,815,462 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2774,470,133 - 74,490,517 (-)NCBI
Gm12258
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391158,737,971 - 58,752,783 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1158,737,984 - 58,752,782 (+)EnsemblGRCm39 Ensembl
GRCm381158,847,162 - 58,861,957 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1158,847,158 - 58,861,956 (+)EnsemblGRCm38mm10GRCm38
MGSCv371158,663,359 - 58,676,079 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361158,663,359 - 58,676,079 (+)NCBIMGSCv36mm8
Celera1163,611,131 - 63,625,944 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1136.33NCBI

Variants

.
Variants in PMS2P3
4 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1593
Count of miRNA genes:677
Interacting mature miRNAs:745
Transcripts:ENST00000275580, ENST00000301956, ENST00000394921, ENST00000418756, ENST00000422064, ENST00000430602, ENST00000434405, ENST00000437568, ENST00000438326, ENST00000529061, ENST00000533167
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4974 1726 2351 6 624 1951 465 2270 7305 6471 53 3734 1 852 1744 1617 174 1

Sequence


Ensembl Acc Id: ENST00000394921
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,747 - 75,528,051 (-)Ensembl
Ensembl Acc Id: ENST00000418756
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,750 - 75,528,123 (-)Ensembl
Ensembl Acc Id: ENST00000422064
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,512,589 - 75,528,148 (-)Ensembl
Ensembl Acc Id: ENST00000430602
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,750 - 75,527,836 (-)Ensembl
Ensembl Acc Id: ENST00000437568
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,511,017 - 75,528,088 (-)Ensembl
Ensembl Acc Id: ENST00000438326
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,516,043 - 75,525,955 (-)Ensembl
Ensembl Acc Id: ENST00000529061
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,510,931 - 75,516,235 (-)Ensembl
Ensembl Acc Id: ENST00000533167
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,510,676 - 75,527,853 (-)Ensembl
Ensembl Acc Id: ENST00000691440
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,512,124 - 75,528,103 (-)Ensembl
Ensembl Acc Id: ENST00000693762
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,747 - 75,528,132 (-)Ensembl
Ensembl Acc Id: ENST00000702274
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,747 - 75,528,096 (-)Ensembl
Ensembl Acc Id: ENST00000845724
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,502,855 - 75,528,138 (-)Ensembl
Ensembl Acc Id: ENST00000845725
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,490,413 - 75,512,638 (-)Ensembl
Ensembl Acc Id: ENST00000845726
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,750 - 75,528,172 (-)Ensembl
Ensembl Acc Id: ENST00000845727
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,751 - 75,528,146 (-)Ensembl
Ensembl Acc Id: ENST00000845728
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,747 - 75,528,118 (-)Ensembl
Ensembl Acc Id: ENST00000845729
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,750 - 75,528,121 (-)Ensembl
Ensembl Acc Id: ENST00000845730
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,747 - 75,528,118 (-)Ensembl
Ensembl Acc Id: ENST00000845731
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,747 - 75,528,103 (-)Ensembl
Ensembl Acc Id: ENST00000845732
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,750 - 75,528,103 (-)Ensembl
Ensembl Acc Id: ENST00000845733
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,750 - 75,528,099 (-)Ensembl
Ensembl Acc Id: ENST00000845734
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,747 - 75,527,990 (-)Ensembl
Ensembl Acc Id: ENST00000845735
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,747 - 75,527,963 (-)Ensembl
Ensembl Acc Id: ENST00000845736
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,749 - 75,527,899 (-)Ensembl
Ensembl Acc Id: ENST00000845737
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,750 - 75,527,889 (-)Ensembl
Ensembl Acc Id: ENST00000845738
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,747 - 75,527,885 (-)Ensembl
Ensembl Acc Id: ENST00000845739
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,750 - 75,527,868 (-)Ensembl
Ensembl Acc Id: ENST00000845740
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,747 - 75,527,673 (-)Ensembl
Ensembl Acc Id: ENST00000845741
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,750 - 75,527,606 (-)Ensembl
Ensembl Acc Id: ENST00000845742
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,510,741 - 75,527,965 (-)Ensembl
Ensembl Acc Id: ENST00000845743
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,510,680 - 75,527,869 (-)Ensembl
Ensembl Acc Id: ENST00000845746
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,512,124 - 75,528,121 (-)Ensembl
Ensembl Acc Id: ENST00000845747
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,512,119 - 75,527,896 (-)Ensembl
Ensembl Acc Id: ENST00000845748
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,512,100 - 75,527,849 (-)Ensembl
Ensembl Acc Id: ENST00000845878
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,502,855 - 75,514,779 (-)Ensembl
Ensembl Acc Id: ENST00000845951
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,746 - 75,514,850 (-)Ensembl
Ensembl Acc Id: ENST00000845952
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,750 - 75,514,825 (-)Ensembl
Ensembl Acc Id: ENST00000845954
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,747 - 75,514,762 (-)Ensembl
Ensembl Acc Id: ENST00000845969
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,510,677 - 75,516,178 (-)Ensembl
Ensembl Acc Id: ENST00000845970
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,545 - 75,512,390 (-)Ensembl
Ensembl Acc Id: ENST00000845972
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,512,124 - 75,515,765 (-)Ensembl
Ensembl Acc Id: ENST00000845973
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,747 - 75,511,302 (-)Ensembl
Ensembl Acc Id: ENST00000845974
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl775,507,750 - 75,511,114 (-)Ensembl
RefSeq Acc Id: NR_028059
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38775,507,747 - 75,528,123 (-)NCBI
GRCh37775,137,069 - 75,157,453 (-)RGD
Celera770,004,871 - 70,025,253 (-)RGD
HuRef770,226,268 - 70,243,191 (-)NCBI
CHM1_1775,067,163 - 75,087,539 (-)NCBI
T2T-CHM13v2.0776,795,078 - 76,815,462 (-)NCBI
CRA_TCAGchr7v2774,470,133 - 74,490,517 (-)ENTREZGENE
Sequence:
Protein Domains
KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q13401-F1-model_v2 AlphaFold Q13401 1-168 view protein structure

Promoters
RGD ID:6805553
Promoter ID:HG_KWN:58124
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000275580,   ENST00000301956,   OTTHUMT00000342862,   OTTHUMT00000342940,   OTTHUMT00000342942,   UC003UDN.1,   UC003UDO.1,   UC003UDP.1,   UC003UDQ.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36774,995,131 - 74,995,631 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:9128 AgrOrtholog
COSMIC PMS2P3 COSMIC
Ensembl Genes ENSG00000127957 Ensembl
  ENSG00000291092 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000845735 ENTREZGENE
Gene3D-CATH 3.30.565.10 UniProtKB/Swiss-Prot
  6.10.140.140 UniProtKB/Swiss-Prot
GTEx ENSG00000127957 GTEx
  ENSG00000291092 GTEx
HGNC ID HGNC:9128 ENTREZGENE
Human Proteome Map PMS2P3 Human Proteome Map
InterPro HATPase_C_sf UniProtKB/Swiss-Prot
  KRAB UniProtKB/Swiss-Prot
  KRAB_dom_sf UniProtKB/Swiss-Prot
  MutL/Mlh/Pms UniProtKB/Swiss-Prot
NCBI Gene PMS2P3 ENTREZGENE
PANTHER MISMATCH REPAIR ENDONUCLEASE PMS2 UniProtKB/Swiss-Prot
  PTHR10073 UniProtKB/Swiss-Prot
Pfam HATPase_c_3 UniProtKB/Swiss-Prot
  KRAB UniProtKB/Swiss-Prot
PharmGKB PA33454 PharmGKB
PROSITE KRAB UniProtKB/Swiss-Prot
SMART KRAB UniProtKB/Swiss-Prot
Superfamily-SCOP SSF109640 UniProtKB/Swiss-Prot
  SSF55874 UniProtKB/Swiss-Prot
UniProt PM2P3_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A6NG70 UniProtKB/Swiss-Prot
  Q3MJ29 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-14 PMS2P3  PMS1 homolog 2, mismatch repair system component pseudogene 3    postmeiotic segregation increased 2 pseudogene 3  Symbol and/or name change 5135510 APPROVED
2011-07-27 PMS2P3  postmeiotic segregation increased 2 pseudogene 3  PMS2L3  postmeiotic segregation increased 2-like 3  Symbol and/or name change 5135510 APPROVED